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Protein

Magnesium transporter ALR2

Gene

ALR2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plasma membrane magnesium transporter.1 Publication

Miscellaneous

Present with 2130 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • inorganic cation transmembrane transporter activity Source: SGD
  • magnesium ion transmembrane transporter activity Source: GO_Central

GO - Biological processi

  • cation transport Source: SGD
  • magnesium ion transport Source: SGD
  • transmembrane transport Source: SGD

Keywordsi

Biological processTransport
LigandMagnesium

Enzyme and pathway databases

BioCyciYEAST:G3O-30415-MONOMER
BRENDAi3.6.3.2 984

Names & Taxonomyi

Protein namesi
Recommended name:
Magnesium transporter ALR2
Alternative name(s):
Aluminum resistance protein 2
Gene namesi
Name:ALR2
Ordered Locus Names:YFL050C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VI

Organism-specific databases

EuPathDBiFungiDB:YFL050C
SGDiS000001844 ALR2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 741CytoplasmicSequence analysisAdd BLAST741
Transmembranei742 – 762HelicalSequence analysisAdd BLAST21
Topological domaini763 – 771ExtracellularSequence analysis9
Transmembranei772 – 792HelicalSequence analysisAdd BLAST21
Topological domaini793 – 858CytoplasmicSequence analysisAdd BLAST66

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002015361 – 858Magnesium transporter ALR2Add BLAST858

Proteomic databases

MaxQBiP43553
PaxDbiP43553
PRIDEiP43553

PTM databases

iPTMnetiP43553

Interactioni

Protein-protein interaction databases

BioGridi31097, 38 interactors
DIPiDIP-4581N
STRINGi4932.YFL050C

Structurei

3D structure databases

ProteinModelPortaliP43553
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000009621
HOGENOMiHOG000171963
InParanoidiP43553
KOiK16073
OrthoDBiEOG092C0RNR

Family and domain databases

InterProiView protein in InterPro
IPR002523 MgTranspt_CorA/ZnTranspt_ZntB
PfamiView protein in Pfam
PF01544 CorA, 1 hit

Sequencei

Sequence statusi: Complete.

P43553-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLSTSFDS SSDLPRSKSV DNTAASMKTG KYPKLENYRQ YSDAQPIRHE
60 70 80 90 100
ALALKVDETK DSRHKFSSSN GENSGVENGG YVEKTNISTS GRMDFEGEAE
110 120 130 140 150
AEAVKRYQLR SFALLSSNAR PSRLAKSETH QKQIHVESIA PSLPKNAALE
160 170 180 190 200
RGHDTALPAG TSSNRCNLEA SSSARTFTSA RKASLVSAIF ETSAESEHGT
210 220 230 240 250
HPKQAKLKRR TYSTISTHSS VNPTTLLTRT ASQKSDMGND TRRIKPLRMD
260 270 280 290 300
SRVSFHSEIS QASRDSQETE EDVCFPMFRL LHTRVNGVDF DELEEYAQIS
310 320 330 340 350
NAERNLSLAN HQRHSERTYN HTDQDTGFTN SASTSGSSAA LKYTPEISRT
360 370 380 390 400
LEKNCSVNEM YVSENNESVR EDDKPDLHPD VTFGRNKIEG EKEGNDSSYS
410 420 430 440 450
RAYYTLQNTE YQIPSRFSFF RSESDETVHA SDIPSLISEG QTFYELFKGG
460 470 480 490 500
DPTWWLDCSC PTDDEMRCIA KTFGIHPLTA EDIRMQETRE KVELFKSYYF
510 520 530 540 550
VCFHTFENDK ESENYLEPIN VYIVVFRSGV LTFHFDPISH CANVRRRVRQ
560 570 580 590 600
LRDYVSVNSD WLCYALIDDI TDSFAPVIQS IEYEADSIDD SVFMTRDMDF
610 620 630 640 650
AAMLQRIGES RRKTMTLMRL LSGKADVIKM FAKRCQDETN GIGPVLKSQT
660 670 680 690 700
NMVNLQAEQE NVNQNNSNNQ ISLSNSYMQT TSQPRGDIAL YLGDIQDHLL
710 720 730 740 750
TMFQNLLAYE KIFSRSHANY LAQLQVESFN SNNKVTEMLG KVTMLGTMLV
760 770 780 790 800
PLNVITGLFG MNVKVPGRNG SIAWWYGILG VLLLLAVISW FLASYWIKKI
810 820 830 840 850
DPPATLNEAA GSGAKSVISS FLPKRDKRFN DDSKNGNARV GVRRKSTVSL

PSRYSRYN
Length:858
Mass (Da):96,684
Last modified:November 1, 1995 - v1
Checksum:i7AAFEC6086FF0618
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA Translation: BAA09191.1
BK006940 Genomic DNA Translation: DAA12390.1
PIRiS56205
RefSeqiNP_116604.1, NM_001179917.1

Genome annotation databases

EnsemblFungiiBAA09191; BAA09191; BAA09191
YFL050C; YFL050C; YFL050C
GeneIDi850494
KEGGisce:YFL050C

Similar proteinsi

Entry informationi

Entry nameiALR2_YEAST
AccessioniPrimary (citable) accession number: P43553
Secondary accession number(s): D6VTI0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 23, 2018
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VI
    Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

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