ID   YFF1_YEAST              Reviewed;         160 AA.
AC   P43552; D6VTH9;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   24-JAN-2024, entry version 149.
DE   RecName: Full=Uncharacterized membrane protein YFL051C;
DE   Flags: Precursor;
GN   OrderedLocusNames=YFL051C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=7670463; DOI=10.1038/ng0795-261;
RA   Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S.,
RA   Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H.,
RA   Eki T.;
RT   "Analysis of the nucleotide sequence of chromosome VI from Saccharomyces
RT   cerevisiae.";
RL   Nat. Genet. 10:261-268(1995).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [4]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 208353 / W303-1A;
RX   PubMed=16847258; DOI=10.1073/pnas.0604075103;
RA   Kim H., Melen K., Oesterberg M., von Heijne G.;
RT   "A global topology map of the Saccharomyces cerevisiae membrane proteome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein.
CC   -!- SIMILARITY: To yeast protein FLO1. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; D50617; BAA09190.1; -; Genomic_DNA.
DR   EMBL; AY558469; AAS56795.1; -; Genomic_DNA.
DR   EMBL; BK006940; DAA12389.1; -; Genomic_DNA.
DR   PIR; S56204; S56204.
DR   RefSeq; NP_116576.1; NM_001179916.1.
DR   AlphaFoldDB; P43552; -.
DR   SMR; P43552; -.
DR   BioGRID; 31096; 78.
DR   DIP; DIP-4270N; -.
DR   IntAct; P43552; 1.
DR   STRING; 4932.YFL051C; -.
DR   PaxDb; 4932-YFL051C; -.
DR   EnsemblFungi; YFL051C_mRNA; YFL051C; YFL051C.
DR   GeneID; 850493; -.
DR   KEGG; sce:YFL051C; -.
DR   AGR; SGD:S000001843; -.
DR   SGD; S000001843; YFL051C.
DR   VEuPathDB; FungiDB:YFL051C; -.
DR   GeneTree; ENSGT00940000180757; -.
DR   HOGENOM; CLU_1590435_0_0_1; -.
DR   InParanoid; P43552; -.
DR   OrthoDB; 2039698at2759; -.
DR   BioCyc; YEAST:G3O-30414-MONOMER; -.
DR   BioGRID-ORCS; 850493; 3 hits in 10 CRISPR screens.
DR   PRO; PR:P43552; -.
DR   Proteomes; UP000002311; Chromosome VI.
DR   RNAct; P43552; Protein.
DR   GO; GO:0071944; C:cell periphery; HDA:SGD.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.120.1560; -; 2.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..160
FT                   /note="Uncharacterized membrane protein YFL051C"
FT                   /id="PRO_0000014318"
FT   TOPO_DOM        24..132
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        156..160
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   160 AA;  18110 MW;  CDA512435B6005B1 CRC64;
     MSIPHSVFSA LLVFVALATT TLASTEACLP TNKREDGMNI NFYEYTIGDQ TTYLEPEYMG
     YEYSNTKKLG SVSGQTNLSI YYSPPCESTP TCVTYAVLKR DEDGYDPCGP LYETKKRDTE
     YCDPNTAYWS SDLFGFYTTP TNVTVEMTGY LIWSMGNRRR
//