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Protein

Putative aryl-alcohol dehydrogenase AAD6

Gene

AAD6

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei76 – 761Proton donorBy similarity

GO - Molecular functioni

  1. aryl-alcohol dehydrogenase (NAD+) activity Source: SGD

GO - Biological processi

  1. cellular aldehyde metabolic process Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciYEAST:YFL056C-MONOMER.
ReactomeiREACT_280760. Aflatoxin activation and detoxification.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aryl-alcohol dehydrogenase AAD6 (EC:1.1.1.-)
Gene namesi
Name:AAD6
Ordered Locus Names:YFL056C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome VI

Organism-specific databases

CYGDiYFL056c.
EuPathDBiFungiDB:YFL056C.
SGDiS000001838. AAD6.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 212212Putative aryl-alcohol dehydrogenase AAD6PRO_0000070367Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP43547.

Interactioni

Protein-protein interaction databases

BioGridi31091. 6 interactions.
DIPiDIP-2015N.
IntActiP43547. 2 interactions.
MINTiMINT-384745.
STRINGi4932.YFL056C.

Structurei

3D structure databases

ProteinModelPortaliP43547.
SMRiP43547. Positions 5-211.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0667.
GeneTreeiENSGT00510000049995.
InParanoidiP43547.
KOiK00100.
OrthoDBiEOG7DRJCT.

Family and domain databases

Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
SUPFAMiSSF51430. SSF51430. 1 hit.

Sequencei

Sequence statusi: Complete.

P43547-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADLFAPAPE PSTELGRLRV LSKSAGIRVS PLILGGMSIG DAWSEILGSM
60 70 80 90 100
SKERAFELLD AFYEAGGNFI DTANNYQNEQ SEAWIGEWMV SRKLRDQIVI
110 120 130 140 150
ATKFTTDYKK YDVGGGKSAN YCGNHKRSLH VSVRDSLRKL QTDWIDILYV
160 170 180 190 200
HWWDYMSSIE EVMDSLHILV QQARSSIWVC LIRLPGLFLR QITTLNLMVK
210
PLLASIKVNG TC
Length:212
Mass (Da):23,919
Last modified:November 1, 1995 - v1
Checksum:iC3FF042B12C91580
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti208 – 2081V → K in AAT93180 (PubMed:17322287).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA. Translation: BAA09185.1.
AY693161 Genomic DNA. Translation: AAT93180.1.
BK006940 Genomic DNA. Translation: DAA12384.1.
PIRiS56199.

Genome annotation databases

EnsemblFungiiYFL056C; YFL056C; YFL056C.
KEGGisce:YFL056C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA. Translation: BAA09185.1.
AY693161 Genomic DNA. Translation: AAT93180.1.
BK006940 Genomic DNA. Translation: DAA12384.1.
PIRiS56199.

3D structure databases

ProteinModelPortaliP43547.
SMRiP43547. Positions 5-211.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31091. 6 interactions.
DIPiDIP-2015N.
IntActiP43547. 2 interactions.
MINTiMINT-384745.
STRINGi4932.YFL056C.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYFL056C; YFL056C; YFL056C.
KEGGisce:YFL056C.

Organism-specific databases

CYGDiYFL056c.
EuPathDBiFungiDB:YFL056C.
SGDiS000001838. AAD6.

Phylogenomic databases

eggNOGiCOG0667.
GeneTreeiENSGT00510000049995.
InParanoidiP43547.
KOiK00100.
OrthoDBiEOG7DRJCT.

Enzyme and pathway databases

BioCyciYEAST:YFL056C-MONOMER.
ReactomeiREACT_280760. Aflatoxin activation and detoxification.

Miscellaneous databases

NextBioi966158.
PROiP43547.

Gene expression databases

GenevestigatoriP43547.

Family and domain databases

Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
SUPFAMiSSF51430. SSF51430. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiAAD6_YEAST
AccessioniPrimary (citable) accession number: P43547
Secondary accession number(s): D6VTH4, E9P925
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 29, 2015
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VI
    Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.