P43547 (AAD6_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative aryl-alcohol dehydrogenase AAD6
EC=1.1.1.-

Gene names

Name:	AAD6
Ordered Locus Names:	YFL056C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	212 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the aldo/keto reductase 2 family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 212	212	Putative aryl-alcohol dehydrogenase AAD6		PRO_0000070367
Sites
	Active site	76	1	Proton donor By similarity
Experimental info
	Sequence conflict	208	1	V → K in AAT93180. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	P43547 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: C3FF042B12C91580	FASTA	212	23,919
	10 20 30 40 50 60 MADLFAPAPE PSTELGRLRV LSKSAGIRVS PLILGGMSIG DAWSEILGSM SKERAFELLD 70 80 90 100 110 120 AFYEAGGNFI DTANNYQNEQ SEAWIGEWMV SRKLRDQIVI ATKFTTDYKK YDVGGGKSAN 130 140 150 160 170 180 YCGNHKRSLH VSVRDSLRKL QTDWIDILYV HWWDYMSSIE EVMDSLHILV QQARSSIWVC 190 200 210 LIRLPGLFLR QITTLNLMVK PLLASIKVNG TC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T. Nat. Genet. 10:261-268(1995) [PubMed: 7670463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D50617 Genomic DNA. Translation: BAA09185.1. AY693161 Genomic DNA. Translation: AAT93180.1. BK006940 Genomic DNA. Translation: DAA12384.1.
PIR	S56199.
RefSeq	NP_116599.1. NM_001179911.1.
3D structure databases
ProteinModelPortal	P43547.
SMR	P43547. Positions 17-211.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-2015N.
IntAct	P43547. 2 interactions.
MINT	MINT-384745.
STRING	P43547.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YFL056C; YFL056C; YFL056C.
GeneID	850488.
KEGG	sce:YFL056C.
NMPDR	fig|4932.3.peg.2222.
Organism-specific databases
CYGD	YFL056c.
SGD	S000001838. AAD6.
Phylogenomic databases
eggNOG	fuNOG05818.
OrthoDB	EOG45TGWW.
Gene expression databases
ArrayExpress	P43547.
Genevestigator	P43547.
GermOnline	YFL056C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001395. Aldo/ket_red. IPR023210. NADP_OxRdtase_dom. [Graphical view]
Gene3D	G3DSA:3.20.20.100. Aldo/ket_red. 1 hit.
KO	K00100.
PANTHER	PTHR11732. Aldo/ket_red. 1 hit.
Pfam	PF00248. Aldo_ket_red. 1 hit. [Graphical view]
SUPFAM	SSF51430. Aldo/ket_red. 1 hit.
ProtoNet	Search...
Other
NextBio	966158.

Entry information

Entry name

AAD6_YEAST

Accession

Primary (citable) accession number: P43547
Secondary accession number(s): D6VTH4, E9P925

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	December 14, 2011
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program