Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P43547 (AAD6_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative aryl-alcohol dehydrogenase AAD6

EC=1.1.1.-
Gene names
Name:AAD6
Ordered Locus Names:YFL056C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length212 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 212212Putative aryl-alcohol dehydrogenase AAD6
PRO_0000070367

Sites

Active site761Proton donor By similarity

Experimental info

Sequence conflict2081V → K in AAT93180. Ref.3

Sequences

Sequence LengthMass (Da)Tools
P43547 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: C3FF042B12C91580

FASTA21223,919
        10         20         30         40         50         60 
MADLFAPAPE PSTELGRLRV LSKSAGIRVS PLILGGMSIG DAWSEILGSM SKERAFELLD 

        70         80         90        100        110        120 
AFYEAGGNFI DTANNYQNEQ SEAWIGEWMV SRKLRDQIVI ATKFTTDYKK YDVGGGKSAN 

       130        140        150        160        170        180 
YCGNHKRSLH VSVRDSLRKL QTDWIDILYV HWWDYMSSIE EVMDSLHILV QQARSSIWVC 

       190        200        210 
LIRLPGLFLR QITTLNLMVK PLLASIKVNG TC 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae."
Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T.
Nat. Genet. 10:261-268(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D50617 Genomic DNA. Translation: BAA09185.1.
AY693161 Genomic DNA. Translation: AAT93180.1.
BK006940 Genomic DNA. Translation: DAA12384.1.
PIRS56199.
RefSeqNP_116599.1. NM_001179911.1.

3D structure databases

ProteinModelPortalP43547.
SMRP43547. Positions 16-212.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid31091. 5 interactions.
DIPDIP-2015N.
IntActP43547. 2 interactions.
MINTMINT-384745.
STRING4932.YFL056C.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYFL056C; YFL056C; YFL056C.
GeneID850488.
KEGGsce:YFL056C.

Organism-specific databases

CYGDYFL056c.
SGDS000001838. AAD6.

Phylogenomic databases

eggNOGCOG0667.
GeneTreeENSGT00510000049995.
KOK00100.
OrthoDBEOG7DRJCT.

Enzyme and pathway databases

BioCycYEAST:YFL056C-MONOMER.

Gene expression databases

GenevestigatorP43547.

Family and domain databases

Gene3D3.20.20.100. 1 hit.
InterProIPR001395. Aldo/ket_red.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERPTHR11732. PTHR11732. 1 hit.
PfamPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
SUPFAMSSF51430. SSF51430. 1 hit.
ProtoNetSearch...

Other

NextBio966158.

Entry information

Entry nameAAD6_YEAST
AccessionPrimary (citable) accession number: P43547
Secondary accession number(s): D6VTH4, E9P925
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 19, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VI

Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families