P43545 (SNZ3_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable pyridoxine biosynthesis protein SNZ3

Alternative name(s):
PDX1 homolog 3

Gene names

Name:	SNZ3
Ordered Locus Names:	YFL059W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May be required for the production of pyridoxine (vitamin B6). Ref.3
Induction	By the absence of external thiamine. Ref.3
Sequence similarities	Belongs to the pdxS/SNZ family.

Ontologies

Keywords
Biological process	Pyridoxine biosynthesis
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pyridoxal phosphate biosynthetic process Inferred from electronic annotation. Source: InterPro pyridoxine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW thiamine biosynthetic process Inferred from mutant phenotype Ref.3. Source: SGD
Molecular function	catalytic activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 298	298	Probable pyridoxine biosynthesis protein SNZ3		PRO_0000109360

Sequences

	Sequence		Length	Mass (Da)
	P43545 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: FDBADC5546C460AC	FASTA	298	32,019
	10 20 30 40 50 60 MSEFKVKTGL AQMLKGGVIM DVVTPEQAII AERAGACAVM ALERIPADMR KSGQVCRMSD 70 80 90 100 110 120 PRMIKEIMEA VSIPVMAKVR IGHFVEAQIL EELQVDYIDE SEVLTPADWT HHIEKHNFKV 130 140 150 160 170 180 PFVCGAKDLG EALRRINEGA AMIRTKGEAG TGDVSEAVKH ITKIKAEIQQ YKENLKTESD 190 200 210 220 230 240 FAAKATELRV PVDLLKTTLS EGKLPVVNFA AGGVATPADA ALLMQLGCEG VFVGSGIFKS 250 260 270 280 290 SDPEKLACAI VEATTHYDNP AKLLQVSSDL GDLMGGISIQ SINEAGGKNG ARLSEIGW

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T. Nat. Genet. 10:261-268(1995) [PubMed: 7670463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6." Rodriguez-Navarro S., Llorente B., Rodriguez-Manzaneque M.T., Ramne A., Uber G., Marchesan D., Dujon B., Herrero E., Sunnerhagen P., Perez-Ortin J.E. Yeast 19:1261-1276(2002) [PubMed: 12271461] [Abstract] Cited for: PROBABLE FUNCTION, INDUCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D50617 Genomic DNA. Translation: BAA09182.1. BK006940 Genomic DNA. Translation: DAA12381.1.
PIR	S56196.
RefSeq	NP_116596.1. NM_001179908.1.
3D structure databases
ProteinModelPortal	P43545.
SMR	P43545. Positions 14-271.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-1644N.
IntAct	P43545. 13 interactions.
MINT	MINT-409112.
STRING	P43545.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YFL059W; YFL059W; YFL059W.
GeneID	850485.
KEGG	sce:YFL059W.
Organism-specific databases
CYGD	YFL059w.
SGD	S000001835. SNZ3.
Phylogenomic databases
eggNOG	fuNOG06628.
GeneTree	EFGT00050000004159.
HOGENOM	HBG292342.
OMA	IPANIRR.
OrthoDB	EOG4C5GTD.
Gene expression databases
Genevestigator	P43545.
GermOnline	YFL059W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR011060. RibuloseP-bd_barrel. IPR001852. Snz1p/Sor1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 2 hits.
KO	K06215.
PANTHER	PTHR22854:SF9. PTHR22854:SF9. 1 hit.
Pfam	PF01680. SOR_SNZ. 1 hit. [Graphical view]
PIRSF	PIRSF029271. Pdx1. 1 hit.
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
TIGRFAMs	TIGR00343. TIGR00343. 1 hit.
PROSITE	PS01235. PDXS_SNZ_1. 1 hit. PS51129. PDXS_SNZ_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	966149.

Entry information

Entry name

SNZ3_YEAST

Accession

Primary (citable) accession number: P43545
Secondary accession number(s): D6VTH1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	December 14, 2011
This is version 95 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program