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Protein

Inner membrane transport protein YnfM

Gene

ynfM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:B1596-MONOMER.
ECOL316407:JW1588-MONOMER.

Protein family/group databases

TCDBi2.A.1.36.1. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane transport protein YnfM
Gene namesi
Name:ynfM
Synonyms:yzyC
Ordered Locus Names:b1596, JW1588
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12951. ynfM.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3838PeriplasmicSequence analysisAdd
BLAST
Transmembranei39 – 5921HelicalSequence analysisAdd
BLAST
Topological domaini60 – 7314CytoplasmicSequence analysisAdd
BLAST
Transmembranei74 – 9421HelicalSequence analysisAdd
BLAST
Topological domaini95 – 1017PeriplasmicSequence analysis
Transmembranei102 – 12221HelicalSequence analysisAdd
BLAST
Topological domaini123 – 1253CytoplasmicSequence analysis
Transmembranei126 – 14621HelicalSequence analysisAdd
BLAST
Topological domaini147 – 1526PeriplasmicSequence analysis
Transmembranei153 – 17321HelicalSequence analysisAdd
BLAST
Topological domaini174 – 19017CytoplasmicSequence analysisAdd
BLAST
Transmembranei191 – 21121HelicalSequence analysisAdd
BLAST
Topological domaini212 – 24130PeriplasmicSequence analysisAdd
BLAST
Transmembranei242 – 26221HelicalSequence analysisAdd
BLAST
Topological domaini263 – 2642CytoplasmicSequence analysis
Transmembranei265 – 28521HelicalSequence analysisAdd
BLAST
Topological domaini286 – 31530PeriplasmicSequence analysisAdd
BLAST
Transmembranei316 – 33621HelicalSequence analysisAdd
BLAST
Topological domaini337 – 36428CytoplasmicSequence analysisAdd
BLAST
Transmembranei365 – 38521HelicalSequence analysisAdd
BLAST
Topological domaini386 – 3872PeriplasmicSequence analysis
Transmembranei388 – 40821HelicalSequence analysisAdd
BLAST
Topological domaini409 – 4179CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 417417Inner membrane transport protein YnfMPRO_0000173411Add
BLAST

Proteomic databases

PaxDbiP43531.

Interactioni

Protein-protein interaction databases

BioGridi4259121. 139 interactions.
STRINGi511145.b1596.

Structurei

3D structure databases

ProteinModelPortaliP43531.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105D94. Bacteria.
ENOG410XP8J. LUCA.
HOGENOMiHOG000217197.
InParanoidiP43531.
KOiK08224.
OMAiNFRLHWH.
PhylomeDBiP43531.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P43531-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRTTTVDGA PASDTDKQSI SQPNQFIKRG TPQFMRVTLA LFSAGLATFA
60 70 80 90 100
LLYCVQPILP VLSQEFGLTP ANSSISLSIS TAMLAIGLLF TGPLSDAIGR
110 120 130 140 150
KPVMVTALLL ASICTLLSTM MTSWHGILIM RALIGLSLSG VAAVGMTYLS
160 170 180 190 200
EEIHPSFVAF SMGLYISGNS IGGMSGRLIS GVFTDFFNWR IALAAIGCFA
210 220 230 240 250
LASALMFWKI LPESRHFRPT SLRPKTLFIN FRLHWRDRGL PLLFAEGFLL
260 270 280 290 300
MGSFVTLFNY IGYRLMLSPW HVSQAVVGLL SLAYLTGTWS SPKAGTMTTR
310 320 330 340 350
YGRGPVMLFS TGVMLFGLLM TLFSSLWLIF AGMLLFSAGF FAAHSVASSW
360 370 380 390 400
IGPRAKRAKG QASSLYLFSY YLGSSIAGTL GGVFWHNYGW NGVGAFIALM
410
LVIALLVGTR LHRRLHA
Length:417
Mass (Da):45,258
Last modified:November 1, 1997 - v2
Checksum:i78862FD89AD1987B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74668.1.
AP009048 Genomic DNA. Translation: BAA15330.1.
AF405541 Genomic DNA. No translation available.
PIRiF64915.
RefSeqiNP_416113.1. NC_000913.3.
WP_000091840.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74668; AAC74668; b1596.
BAA15330; BAA15330; BAA15330.
GeneIDi946138.
KEGGiecj:JW1588.
eco:b1596.
PATRICi32118494. VBIEscCol129921_1667.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74668.1.
AP009048 Genomic DNA. Translation: BAA15330.1.
AF405541 Genomic DNA. No translation available.
PIRiF64915.
RefSeqiNP_416113.1. NC_000913.3.
WP_000091840.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP43531.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259121. 139 interactions.
STRINGi511145.b1596.

Protein family/group databases

TCDBi2.A.1.36.1. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP43531.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74668; AAC74668; b1596.
BAA15330; BAA15330; BAA15330.
GeneIDi946138.
KEGGiecj:JW1588.
eco:b1596.
PATRICi32118494. VBIEscCol129921_1667.

Organism-specific databases

EchoBASEiEB2785.
EcoGeneiEG12951. ynfM.

Phylogenomic databases

eggNOGiENOG4105D94. Bacteria.
ENOG410XP8J. LUCA.
HOGENOMiHOG000217197.
InParanoidiP43531.
KOiK08224.
OMAiNFRLHWH.
PhylomeDBiP43531.

Enzyme and pathway databases

BioCyciEcoCyc:B1596-MONOMER.
ECOL316407:JW1588-MONOMER.

Miscellaneous databases

PROiP43531.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYNFM_ECOLI
AccessioniPrimary (citable) accession number: P43531
Secondary accession number(s): P76886, P77705
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1997
Last modified: September 7, 2016
This is version 117 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.