Reviewed, UniProtKB/Swiss-Prot P43469 (AGAL2_PEDPE)

Names and origin

Protein names

Recommended name:
    Alpha-galactosidase 2
    EC=3.2.1.22
Alternative name(s):
    Melibiase

Gene names

Name:

agaS

Organism

Pediococcus pentosaceus

Taxonomic identifier

1255 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Pediococcus

Protein attributes

Sequence length	719 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Alpha-galactosidase associated with the sucrase operon.
Catalytic activity	Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase.
Sequence similarities	Belongs to the glycosyl hydrolase 36 family.

Ontologies

Keywords
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	alpha-galactosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 719	719	Alpha-galactosidase 2		PRO_0000134875

Sequences

	Sequence		Length	Mass (Da)
	P43469-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: CB03B93A5EC8A403	FASTA	719	81,368
	10 20 30 40 50 60 MPVEYDPKTG LINLHNDQIS YVIQILAHRY PVHRYFGRYF SKQPYFEPMP SGSHAFANDP 70 80 90 100 110 120 TERFPYSVTS LPLEYSTIGS GDYRQPAYVI KDANNQLLPI LEYTGFSVND QPINSRQLPP 130 140 150 160 170 180 TVSKHTPVTT LVIHLTDAVT KLQMDLNYTI FENQPLILRS TTLRHHGTTN LQVTALSSAQ 190 200 210 220 230 240 LDLPTDQYTA LTLSGTHAHE ANPSFNRLHP GLQTVRSLRG TSGPQHQPFM ALAEPNTTEL 250 260 270 280 290 300 AGTVIGCALA WSGNFDSTVE VDQYQHSRLT IGLEPDTFEW QLKPNSSFQT PEAVLTWTNT 310 320 330 340 350 360 GFNGMSQVFH DFSYQLMPSQ TNIPSVLNTW ETLTFAVSES KVQHLIEHAH QLGLQMLVLD 370 380 390 400 410 420 DGWFVNRNGE NGQLGDWFVD PIKFPNGLNP LAQQAHHHRM KFGLWVEPEM ITTNSQLYQQ 430 440 450 460 470 480 HPDWVLQYVD RTPITARHQL VLDLSQAAVR DHLITTLTNL VQNNQLDYLK WDMNRHLTQV 490 500 510 520 530 540 GSTHLPAAQQ GELYHRYVCG LYDILTRLKR ACPKLIIENC SAGGGRFDFG MLPYTNQTWI 550 560 570 580 590 600 SDLTDPVDRA TIENGFSYLF PPRIFSNHIT ASPNAQNGRI TPFETRLQLA CIGQLGLELN 610 620 630 640 650 660 PKQLAPSEQQ LLRGALIKYQ QLKSTFIKAH FYRLPTTRHV VAWLIVTADK KQAICCYLNG 670 680 690 700 710 LNSRVKTQHP LPLHYLDAEL AYSDSSGNRY TGHQLNTMGI PLKPTNADFT SQLIYLCQN

References

[1]	"The sucrose and raffinose operons of Pediococcus pentosaceus PPE1.0." Leenhouts K.J., Bolhuis A.A., Kok J.J., Venema G.G. Submitted (APR-1994) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: PPE1.0.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L32093 Genomic DNA. Translation: AAA25566.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH36. Glycoside Hydrolase Family 36.
Enzyme and pathway databases
BRENDA	3.2.1.22. 1184.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR002252. Glyco_hydro_36. IPR000111. Glyco_hydro_GHD. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF02065. Melibiase. 1 hit. [Graphical view]
PIRSF	PIRSF005536. Agal. 1 hit.
PRINTS	PR00743. GLHYDRLASE36.
PROSITE	PS00512. ALPHA_GALACTOSIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AGAL2_PEDPE

Accession

Primary (citable) accession number: P43469

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	June 16, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)