P43467 (AGAL1_PEDPE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Alpha-galactosidase 1
EC=3.2.1.22

Alternative name(s):
Melibiase

Gene names

Name:

agaR

Organism

Pediococcus pentosaceus

Taxonomic identifier

1255 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Pediococcus

Protein attributes

Sequence length	733 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Alpha-galactosidase associated with the raffinose operon.
Catalytic activity	Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.
Sequence similarities	Belongs to the glycosyl hydrolase 36 family.

Ontologies

Keywords
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	raffinose alpha-galactosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 733	733	Alpha-galactosidase 1		PRO_0000134874

Sequences

	Sequence		Length	Mass (Da)
	P43467 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 7732ACFDB655EE88	FASTA	733	83,314
	10 20 30 40 50 60 MSLITVDQAN RVFHLHNQTL SYIFAVEQGG TLSHLYFGGH VDHYHGELRY PRVDRGFSGN 70 80 90 100 110 120 LPGSTDRTFS RDTLPKEYST AGEMDYHLPA AIVRHTDGAN ALYLVYQGYR IEAGKPKLSG 130 140 150 160 170 180 LPAAFVEDET EAETLTIVLV DQVSQVEFDL QYTIYRDRPV VTRSVQVCNQ GDHAVNLEKV 190 200 210 220 230 240 ASMQIDFTDR QFETITLPGA HANERHPERG SINYGIQTFG SLRGTSSHQM NPFLALVDHT 250 260 270 280 290 300 TTEFSGDAYG FNLVYSGNHA FELEKDQLDQ LHLMVGINSY NFNWQLKAGA TFQTPEVLMV 310 320 330 340 350 360 YTNKGLNAMS QAYHHLIRER VVRSEFKNQE RPIVVNNWEA TFFDFNEAKL KPIVDEAKQL 370 380 390 400 410 420 GIEMFVLDDG WFGHRDDDNS SLGDWQVDHR KFPQGLNHFV KYVHEQGLKF GIWLEPEMIS 430 440 450 460 470 480 YDSKLYQQHP DYLMQVPGRS PSPSRNQYIL DLGRQAVRNN IFDQLDQLLK SKQIDYIKWD 490 500 510 520 530 540 MNRHLSDIYS VALPPERQGE VYHRYVLGLY ELLERLTTAY PHILFEGCSG GGGRFDAGMA 550 560 570 580 590 600 YYMPQIWASD NTDAVARLTI QYGTSLAYPI SLATAHVSVS PNQQTGRETS MSTRSAVAAS 610 620 630 640 650 660 GVLGYELDLT QLSSADKQIV QKQVVQYKQI RPLIQFGEFY RLKSPITSNQ AAWMFVSPQQ 670 680 690 700 710 720 DEAIVMVFNL TSYAQPSLTK TKLVGLNPKL NYQNIATKAI FGGDELMQLG FYDPVVYQDY 730 TTKVYHFKAV TEN

References

[1]	"The sucrose and raffinose operons of Pediococcus pentosaceus PPE1.0." Leenhouts K.K.J., Bolhuis A.A., Kok J.J., Venema G.G. Submitted (APR-1994) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: PPE1.0.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z32771 Genomic DNA. Translation: CAA83665.1. L32093 Genomic DNA. Translation: AAA25564.1.
PIR	S44254.
3D structure databases
ProteinModelPortal	P43467.
ModBase	Search...
Protein family/group databases
CAZy	GH36. Glycoside Hydrolase Family 36.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR002252. Glyco_hydro_36. IPR000111. Glyco_hydro_GHD. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF02065. Melibiase. 1 hit. [Graphical view]
PIRSF	PIRSF005536. Agal. 1 hit.
PRINTS	PR00743. GLHYDRLASE36.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00512. ALPHA_GALACTOSIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AGAL1_PEDPE

Accession

Primary (citable) accession number: P43467

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	July 27, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program