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Protein

Transcriptional activator AggR

Gene

aggR

Organism
Escherichia coli
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Transcriptional activator of aggregative adherence fimbria I expression in enteroaggregative E.coli.1 Publication

Miscellaneous

Encoded on an unnamed 60MDa plasmid.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi180 – 199H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional activator AggR1 Publication
Alternative name(s):
AAF/I regulatory protein
Gene namesi
Name:aggR
Encoded oniPlasmid unnamed0 Publication
OrganismiEscherichia coli
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Pathology & Biotechi

Disruption phenotypei

Loss of autoagglutination, hemagglutination and aggregative adherence to human epithelial HEp-2 cells, loss of aggregative adherence fimbria I expression.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001944961 – 265Transcriptional activator AggRAdd BLAST265

Proteomic databases

PRIDEiP43464

Structurei

3D structure databases

ProteinModelPortaliP43464
SMRiP43464
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

OMAiIMTTEVN

Family and domain databases

InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR018060 HTH_AraC
IPR018062 HTH_AraC-typ_CS
IPR020449 Tscrpt_reg_HTH_AraC-type
PfamiView protein in Pfam
PF12833 HTH_18, 1 hit
PRINTSiPR00032 HTHARAC
SMARTiView protein in SMART
SM00342 HTH_ARAC, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00041 HTH_ARAC_FAMILY_1, 1 hit
PS01124 HTH_ARAC_FAMILY_2, 1 hit

Sequencei

Sequence statusi: Complete.

P43464-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLKQNIEKE IIKINNIRIH QYTVLYTSNC TIDVYTKEGS NTYLRNELIF
60 70 80 90 100
LERGINISVR LQKKKSTVNP FIAIRLSSDT LRRLKDALMI IYGISKVDAC
110 120 130 140 150
SCPNWSKGII VADADDSVLD TFKSIDHNDD SRITSDLIYL ISKIENNRKI
160 170 180 190 200
IESIYISAVS FFSDKVRNTI EKDLSKRWTL AIIADEFNVS EITIRKRLES
210 220 230 240 250
EYITFNQILM QSRMSKAALL LLDNSYQISQ ISNMIGFSST SYFIRLFVKH
260
FGITPKQFLT YFKSQ
Length:265
Mass (Da):30,690
Last modified:November 1, 1995 - v1
Checksum:iE29828954072075A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z32523 Genomic DNA Translation: CAA83535.1
Z18751 Genomic DNA Translation: CAA79242.1
PIRiS32735
RefSeqiWP_000769457.1, NZ_PDEE01000003.1
YP_006940465.1, NC_019000.1

Genome annotation databases

GeneIDi13877411
35548269

Entry informationi

Entry nameiAGGR_ECOLX
AccessioniPrimary (citable) accession number: P43464
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Plasmid
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Main funding by: National Institutes of Health