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Protein

V-type sodium ATPase subunit K

Gene

ntpK

Organism
Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in ATP-driven sodium extrusion.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14153.

Protein family/group databases

TCDBi3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
V-type sodium ATPase subunit K
Alternative name(s):
Na(+)-translocating ATPase subunit K
Sodium ATPase proteolipid component
Gene namesi
Name:ntpK
Synonyms:ntpN
Ordered Locus Names:EHR_08240
OrganismiEnterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
Taxonomic identifieri768486 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
Proteomesi
  • UP000002895 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
Transmembranei60 – 80HelicalSequence analysisAdd BLAST21
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Transmembranei132 – 152HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000717811 – 156V-type sodium ATPase subunit KAdd BLAST156

Post-translational modificationi

The N-terminus is blocked.

Interactioni

Protein-protein interaction databases

DIPiDIP-46127N.

Structurei

Secondary structure

1156
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi2 – 7Combined sources6
Turni8 – 11Combined sources4
Helixi12 – 45Combined sources34
Helixi49 – 51Combined sources3
Helixi52 – 60Combined sources9
Helixi61 – 63Combined sources3
Helixi64 – 78Combined sources15
Beta strandi82 – 84Combined sources3
Helixi86 – 123Combined sources38
Helixi125 – 127Combined sources3
Helixi128 – 136Combined sources9
Helixi139 – 155Combined sources17

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BL2X-ray2.10A/B/C/D/E/F/G/H/I/J1-156[»]
2CYDX-ray2.80A/B/C/D/E/F/G/H/I/J1-156[»]
2DB4X-ray2.40A/B/C/D/E/F/G/H/I/J1-156[»]
3AOUX-ray3.14A/B/C/D/E/F/G/H/I/J1-156[»]
ProteinModelPortaliP43457.
SMRiP43457.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP43457.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

KOiK02124.
OrthoDBiPOG091H1BS0.

Family and domain databases

InterProiIPR002379. ATPase_proteolipid_c-like_dom.
IPR000245. ATPase_proteolipid_csu.
[Graphical view]
PfamiPF00137. ATP-synt_C. 2 hits.
[Graphical view]
PRINTSiPR00122. VACATPASE.
SUPFAMiSSF81333. SSF81333. 2 hits.

Sequencei

Sequence statusi: Complete.

P43457-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMDYLITQNG GMVFAVLAMA TATIFSGIGS AKGVGMTGEA AAALTTSQPE
60 70 80 90 100
KFGQALILQL LPGTQGLYGF VIAFLIFINL GSDMSVVQGL NFLGASLPIA
110 120 130 140 150
FTGLFSGIAQ GKVAAAGIQI LAKKPEHATK GIIFAAMVET YAILGFVISF

LLVLNA
Length:156
Mass (Da):16,037
Last modified:November 1, 1995 - v1
Checksum:i650D7F4633EB2E0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D16334 Genomic DNA. Translation: BAA03841.1.
D17462 Genomic DNA. Translation: BAA04271.1.
X76913 Genomic DNA. Translation: CAA54237.1.
CP003504 Genomic DNA. Translation: AFM70575.1.
PIRiC54392.
RefSeqiWP_010738015.1. NZ_KB946231.1.

Genome annotation databases

EnsemblBacteriaiAFM70575; AFM70575; EHR_08240.
GeneIDi13177589.
KEGGiehr:EHR_08240.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D16334 Genomic DNA. Translation: BAA03841.1.
D17462 Genomic DNA. Translation: BAA04271.1.
X76913 Genomic DNA. Translation: CAA54237.1.
CP003504 Genomic DNA. Translation: AFM70575.1.
PIRiC54392.
RefSeqiWP_010738015.1. NZ_KB946231.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BL2X-ray2.10A/B/C/D/E/F/G/H/I/J1-156[»]
2CYDX-ray2.80A/B/C/D/E/F/G/H/I/J1-156[»]
2DB4X-ray2.40A/B/C/D/E/F/G/H/I/J1-156[»]
3AOUX-ray3.14A/B/C/D/E/F/G/H/I/J1-156[»]
ProteinModelPortaliP43457.
SMRiP43457.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-46127N.

Protein family/group databases

TCDBi3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFM70575; AFM70575; EHR_08240.
GeneIDi13177589.
KEGGiehr:EHR_08240.

Phylogenomic databases

KOiK02124.
OrthoDBiPOG091H1BS0.

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14153.

Miscellaneous databases

EvolutionaryTraceiP43457.

Family and domain databases

InterProiIPR002379. ATPase_proteolipid_c-like_dom.
IPR000245. ATPase_proteolipid_csu.
[Graphical view]
PfamiPF00137. ATP-synt_C. 2 hits.
[Graphical view]
PRINTSiPR00122. VACATPASE.
SUPFAMiSSF81333. SSF81333. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiNTPK_ENTHA
AccessioniPrimary (citable) accession number: P43457
Secondary accession number(s): I6S1L2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.