P43456 (NTPC_ENTHR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type sodium ATPase subunit C

Alternative name(s):
Na(+)-translocating ATPase subunit C
V-type sodium pump subunit C

Gene names

Name:	ntpC
Synonyms:	ntpP

Organism

Enterococcus hirae

Taxonomic identifier

1354 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Enterococcaceae › Enterococcus

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Involved in ATP-driven sodium extrusion. HAMAP MF_00314
Sequence similarities	Belongs to the V-ATPase V0D/AC39 subunit family.

Ontologies

Keywords
Biological process	Ion transport Sodium transport Transport
Ligand	Sodium
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro sodium ion transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	proton-transporting two-sector ATPase complex, catalytic domain Inferred from electronic annotation. Source: InterPro proton-transporting two-sector ATPase complex, proton-transporting domain Inferred from electronic annotation. Source: InterPro
Molecular function	proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 328	328	V-type sodium ATPase subunit C HAMAP MF_00314		PRO_0000119377

Sequences

	Sequence		Length	Mass (Da)
	P43456 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 44B2D7908CD835E7	FASTA	328	38,163
	10 20 30 40 50 60 MEYHELNPLI RGRELELISK DTFEQMIQTD SIDSLGEILQ STIYQPYIYD GFDKDFEANL 70 80 90 100 110 120 SQERSKLFQW LKESAPEPEI VWIYTMRYTF HNLKVLTKAE ITGQNLDHLY IHDGFYSLEV 130 140 150 160 170 180 LKDAIHTQVS VELPDSLMDY IREVHEYCEE STILQGIDVI YDRCFLTEQR RLGEQLGYPE 190 200 210 220 230 240 LLEEIIAFID LTNITTTARG ILQHRSAGFM TTVISSSGSI PKDTLLSFVR GEMASFTQFL 250 260 270 280 290 300 LTTDYSELLK QVIHEEQIDL VSLEQLKDDY LSSFYQVAQT QAFGPLPLLA FLNAKEVESK 310 320 NLRLLIIGKR NHFSLEQLKE RMRQVYDL

References

[1]

"Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae." Takase K., Kakinuma S., Yamato I., Konishi K., Igarashi K., Kakinuma Y. J. Biol. Chem. 269:11037-11044(1994) [PubMed: 8157629] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-16. Strain: ATCC 8043 / DSM 20160 / JCM 8729 / LMG 6399 / NCIMB 6459.

[2]

"Operon of vacuolar-type Na(+)-ATPase of Enterococcus hirae." Solioz M., Davies K. J. Biol. Chem. 269:9453-9459(1994) [PubMed: 8144530] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 8043 / DSM 20160 / JCM 8729 / LMG 6399 / NCIMB 6459.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D17462 Genomic DNA. Translation: BAA04273.1. X76913 Genomic DNA. Translation: CAA54239.1.
PIR	E54392.
3D structure databases
ProteinModelPortal	P43456.
ModBase	Search...
Protein family/group databases
TCDB	3.A.2.2.2. H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) superfamily.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
BioCyc	MetaCyc:MONOMER-14148.
Family and domain databases
HAMAP	MF_00314. ATP_synth_C_arch. [Tree]
InterPro	IPR014272. ATPase_A1-cplx_csu. IPR002843. ATPase_V0/A0-cplx_csu/dsu. [Graphical view]
Pfam	PF01992. vATP-synt_AC39. 1 hit. [Graphical view]
SUPFAM	SSF103486. ATPase_V0/A0_c/d. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NTPC_ENTHR

Accession

Primary (citable) accession number: P43456

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 31, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program