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P43456

- NTPC_ENTHA

UniProt

P43456 - NTPC_ENTHA

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Protein

V-type sodium ATPase subunit C

Gene

ntpC

Organism
Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Involved in ATP-driven sodium extrusion.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. proton-transporting ATPase activity, rotational mechanism Source: InterPro
  3. proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-HAMAP

GO - Biological processi

  1. plasma membrane ATP synthesis coupled proton transport Source: UniProtKB-HAMAP
  2. sodium ion transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14148.

Protein family/group databases

TCDBi3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
V-type sodium ATPase subunit C
Alternative name(s):
Na(+)-translocating ATPase subunit C
V-type sodium pump subunit C
Gene namesi
Name:ntpC
Synonyms:ntpP
Ordered Locus Names:EHR_08250
OrganismiEnterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
Taxonomic identifieri768486 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
ProteomesiUP000002895: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. proton-transporting V-type ATPase, V0 domain Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 328328V-type sodium ATPase subunit CPRO_0000119377Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP43456.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the V-ATPase V0D/AC39 subunit family.Curated

Phylogenomic databases

KOiK02119.

Family and domain databases

HAMAPiMF_00314. ATP_synth_C_arch.
InterProiIPR014272. ATPase_V0-cplx_c_su.
IPR002843. ATPase_V0-cplx_csu/dsu.
[Graphical view]
PfamiPF01992. vATP-synt_AC39. 1 hit.
[Graphical view]
SUPFAMiSSF103486. SSF103486. 1 hit.

Sequencei

Sequence statusi: Complete.

P43456 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEYHELNPLI RGRELELISK DTFEQMIQTD SIDSLGEILQ STIYQPYIYD
60 70 80 90 100
GFDKDFEANL SQERSKLFQW LKESAPEPEI VWIYTMRYTF HNLKVLTKAE
110 120 130 140 150
ITGQNLDHLY IHDGFYSLEV LKDAIHTQVS VELPDSLMDY IREVHEYCEE
160 170 180 190 200
STILQGIDVI YDRCFLTEQR RLGEQLGYPE LLEEIIAFID LTNITTTARG
210 220 230 240 250
ILQHRSAGFM TTVISSSGSI PKDTLLSFVR GEMASFTQFL LTTDYSELLK
260 270 280 290 300
QVIHEEQIDL VSLEQLKDDY LSSFYQVAQT QAFGPLPLLA FLNAKEVESK
310 320
NLRLLIIGKR NHFSLEQLKE RMRQVYDL
Length:328
Mass (Da):38,163
Last modified:November 1, 1995 - v1
Checksum:i44B2D7908CD835E7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D17462 Genomic DNA. Translation: BAA04273.1.
X76913 Genomic DNA. Translation: CAA54239.1.
CP003504 Genomic DNA. Translation: AFM70577.1.
PIRiE54392.
RefSeqiWP_010738013.1. NZ_KB946231.1.
YP_006487468.1. NC_018081.1.

Genome annotation databases

EnsemblBacteriaiAFM70577; AFM70577; EHR_08250.
GeneIDi13177591.
KEGGiehr:EHR_08250.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D17462 Genomic DNA. Translation: BAA04273.1 .
X76913 Genomic DNA. Translation: CAA54239.1 .
CP003504 Genomic DNA. Translation: AFM70577.1 .
PIRi E54392.
RefSeqi WP_010738013.1. NZ_KB946231.1.
YP_006487468.1. NC_018081.1.

3D structure databases

ProteinModelPortali P43456.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

TCDBi 3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFM70577 ; AFM70577 ; EHR_08250 .
GeneIDi 13177591.
KEGGi ehr:EHR_08250.

Phylogenomic databases

KOi K02119.

Enzyme and pathway databases

BioCyci MetaCyc:MONOMER-14148.

Family and domain databases

HAMAPi MF_00314. ATP_synth_C_arch.
InterProi IPR014272. ATPase_V0-cplx_c_su.
IPR002843. ATPase_V0-cplx_csu/dsu.
[Graphical view ]
Pfami PF01992. vATP-synt_AC39. 1 hit.
[Graphical view ]
SUPFAMi SSF103486. SSF103486. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae."
    Takase K., Kakinuma S., Yamato I., Konishi K., Igarashi K., Kakinuma Y.
    J. Biol. Chem. 269:11037-11044(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-16.
    Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
  2. "Operon of vacuolar-type Na(+)-ATPase of Enterococcus hirae."
    Solioz M., Davies K.
    J. Biol. Chem. 269:9453-9459(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
  3. "Genome sequence of Enterococcus hirae (Streptococcus faecalis) ATCC 9790, a model organism for the study of ion transport, bioenergetics, and copper homeostasis."
    Gaechter T., Wunderlin C., Schmidheini T., Solioz M.
    J. Bacteriol. 194:5126-5127(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.

Entry informationi

Entry nameiNTPC_ENTHA
AccessioniPrimary (citable) accession number: P43456
Secondary accession number(s): I6SYM8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 1, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3