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P43456

- NTPC_ENTHA

UniProt

P43456 - NTPC_ENTHA

Protein

V-type sodium ATPase subunit C

Gene

ntpC

Organism
Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Involved in ATP-driven sodium extrusion.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. proton-transporting ATPase activity, rotational mechanism Source: InterPro
    3. proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-HAMAP

    GO - Biological processi

    1. plasma membrane ATP synthesis coupled proton transport Source: UniProtKB-HAMAP
    2. sodium ion transport Source: UniProtKB-KW

    Keywords - Biological processi

    Ion transport, Sodium transport, Transport

    Keywords - Ligandi

    Sodium

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-14148.

    Protein family/group databases

    TCDBi3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    V-type sodium ATPase subunit C
    Alternative name(s):
    Na(+)-translocating ATPase subunit C
    V-type sodium pump subunit C
    Gene namesi
    Name:ntpC
    Synonyms:ntpP
    Ordered Locus Names:EHR_08250
    OrganismiEnterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
    Taxonomic identifieri768486 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
    ProteomesiUP000002895: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. proton-transporting V-type ATPase, V0 domain Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 328328V-type sodium ATPase subunit CPRO_0000119377Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP43456.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the V-ATPase V0D/AC39 subunit family.Curated

    Phylogenomic databases

    KOiK02119.

    Family and domain databases

    HAMAPiMF_00314. ATP_synth_C_arch.
    InterProiIPR014272. ATPase_V0-cplx_c_su.
    IPR002843. ATPase_V0-cplx_csu/dsu.
    [Graphical view]
    PfamiPF01992. vATP-synt_AC39. 1 hit.
    [Graphical view]
    SUPFAMiSSF103486. SSF103486. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P43456-1 [UniParc]FASTAAdd to Basket

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    MEYHELNPLI RGRELELISK DTFEQMIQTD SIDSLGEILQ STIYQPYIYD    50
    GFDKDFEANL SQERSKLFQW LKESAPEPEI VWIYTMRYTF HNLKVLTKAE 100
    ITGQNLDHLY IHDGFYSLEV LKDAIHTQVS VELPDSLMDY IREVHEYCEE 150
    STILQGIDVI YDRCFLTEQR RLGEQLGYPE LLEEIIAFID LTNITTTARG 200
    ILQHRSAGFM TTVISSSGSI PKDTLLSFVR GEMASFTQFL LTTDYSELLK 250
    QVIHEEQIDL VSLEQLKDDY LSSFYQVAQT QAFGPLPLLA FLNAKEVESK 300
    NLRLLIIGKR NHFSLEQLKE RMRQVYDL 328
    Length:328
    Mass (Da):38,163
    Last modified:November 1, 1995 - v1
    Checksum:i44B2D7908CD835E7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D17462 Genomic DNA. Translation: BAA04273.1.
    X76913 Genomic DNA. Translation: CAA54239.1.
    CP003504 Genomic DNA. Translation: AFM70577.1.
    PIRiE54392.
    RefSeqiWP_010738013.1. NZ_KB946231.1.
    YP_006487468.1. NC_018081.1.

    Genome annotation databases

    EnsemblBacteriaiAFM70577; AFM70577; EHR_08250.
    GeneIDi13177591.
    KEGGiehr:EHR_08250.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D17462 Genomic DNA. Translation: BAA04273.1 .
    X76913 Genomic DNA. Translation: CAA54239.1 .
    CP003504 Genomic DNA. Translation: AFM70577.1 .
    PIRi E54392.
    RefSeqi WP_010738013.1. NZ_KB946231.1.
    YP_006487468.1. NC_018081.1.

    3D structure databases

    ProteinModelPortali P43456.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    TCDBi 3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFM70577 ; AFM70577 ; EHR_08250 .
    GeneIDi 13177591.
    KEGGi ehr:EHR_08250.

    Phylogenomic databases

    KOi K02119.

    Enzyme and pathway databases

    BioCyci MetaCyc:MONOMER-14148.

    Family and domain databases

    HAMAPi MF_00314. ATP_synth_C_arch.
    InterProi IPR014272. ATPase_V0-cplx_c_su.
    IPR002843. ATPase_V0-cplx_csu/dsu.
    [Graphical view ]
    Pfami PF01992. vATP-synt_AC39. 1 hit.
    [Graphical view ]
    SUPFAMi SSF103486. SSF103486. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae."
      Takase K., Kakinuma S., Yamato I., Konishi K., Igarashi K., Kakinuma Y.
      J. Biol. Chem. 269:11037-11044(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-16.
      Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
    2. "Operon of vacuolar-type Na(+)-ATPase of Enterococcus hirae."
      Solioz M., Davies K.
      J. Biol. Chem. 269:9453-9459(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
    3. "Genome sequence of Enterococcus hirae (Streptococcus faecalis) ATCC 9790, a model organism for the study of ion transport, bioenergetics, and copper homeostasis."
      Gaechter T., Wunderlin C., Schmidheini T., Solioz M.
      J. Bacteriol. 194:5126-5127(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.

    Entry informationi

    Entry nameiNTPC_ENTHA
    AccessioniPrimary (citable) accession number: P43456
    Secondary accession number(s): I6SYM8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3