P43455 (NTPG_ENTHA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type sodium ATPase subunit G

Alternative name(s):
Na(+)-translocating ATPase subunit G
V-type sodium pump subunit G

Gene names

Name:	ntpG
Synonyms:	ntpQ
Ordered Locus Names:	EHR_08255

Organism

Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258) [Complete proteome] [HAMAP]

Taxonomic identifier

768486 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Enterococcaceae › Enterococcus › Enterococcus hirae

Protein attributes

Sequence length	103 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Involved in ATP-driven sodium extrusion. HAMAP-Rule MF_00312
Sequence similarities	Belongs to the V-ATPase F subunit family.

Ontologies

Keywords
Biological process	Ion transport Sodium transport Transport
Ligand	Sodium
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological_process	plasma membrane ATP synthesis coupled proton transport Inferred from electronic annotation. Source: HAMAP sodium ion transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP proton-transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 103

103

V-type sodium ATPase subunit G HAMAP-Rule MF_00312

PRO_0000144830

Secondary structure

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103

Helix Strand Turn

Details...

Beta strand

2 – 9

8

Helix

11 – 14

4

Helix

15 – 20

6

Beta strand

23 – 25

3

Helix

30 – 42

13

Beta strand

45 – 51

7

Helix

52 – 55

4

Helix

59 – 66

8

Beta strand

68 – 70

3

Beta strand

72 – 76

5

Helix

85 – 97

13

Sequences

	Sequence		Length	Mass (Da)
	P43455 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 5F452721633D3960	FASTA	103	11,410
	10 20 30 40 50 60 MTYKIGVVGD KDSVSPFRLF GFDVQHGTTK TEIRKTIDEM AKNEYGVIYI TEQCANLVPE 70 80 90 100 TIERYKGQLT PAIILIPSHQ GTLGIGLEEI QNSVEKAVGQ NIL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae." Takase K., Kakinuma S., Yamato I., Konishi K., Igarashi K., Kakinuma Y. J. Biol. Chem. 269:11037-11044(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
[2]	"Operon of vacuolar-type Na(+)-ATPase of Enterococcus hirae." Solioz M., Davies K. J. Biol. Chem. 269:9453-9459(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
[3]	"Genome sequence of Enterococcus hirae (Streptococcus faecalis) ATCC 9790, a model organism for the study of ion transport, bioenergetics, and copper homeostasis." Gaechter T., Wunderlin C., Schmidheini T., Solioz M. J. Bacteriol. 194:5126-5127(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

D17462 Genomic DNA. Translation: BAA04274.1.
X76913 Genomic DNA. Translation: CAA54240.1.
CP003504 Genomic DNA. Translation: AFM70578.1.

PIR

F54392.

RefSeq

YP_006487469.1. NC_018081.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3AON	X-ray	2.00	B	1-103	[»]
3VR4	X-ray	2.17	H	1-103	[»]
3VR5	X-ray	3.90	H	1-103	[»]
3VR6	X-ray	2.68	H	1-103	[»]

ProteinModelPortal

P43455.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-59797N.

Protein family/group databases

TCDB

3.A.2.2.2. H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) superfamily.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

13177592.

KEGG

ehr:EHR_08255.

Organism-specific databases

CMR

Search...

Phylogenomic databases

KO

K02122.

Enzyme and pathway databases

BioCyc

EHIR768486:GLCW-1644-MONOMER.
MetaCyc:MONOMER-14152.

Family and domain databases

Gene3D

3.40.50.10580. 1 hit.

HAMAP

MF_00312. ATP_synth_F_arch.

InterPro

IPR008218. ATPase_V1-cplx_f_g_su.
IPR022944. ATPase_V1-cplx_fsu_bac/arc.
[Graphical view]

Pfam

PF01990. ATP-synt_F. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

NTPG_ENTHA

Accession

Primary (citable) accession number: P43455
Secondary accession number(s): I6SD39

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 29, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program