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P43435

- NTPD_ENTHA

UniProt

P43435 - NTPD_ENTHA

Protein

V-type sodium ATPase subunit D

Gene

ntpD

Organism
Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 2 (09 Jan 2013)
      Previous versions | rss
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    Functioni

    Involved in ATP-driven sodium extrusion.1 Publication

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-HAMAP

    GO - Biological processi

    1. plasma membrane ATP synthesis coupled proton transport Source: UniProtKB-HAMAP
    2. sodium ion transport Source: UniProtKB-KW

    Keywords - Biological processi

    Ion transport, Sodium transport, Transport

    Keywords - Ligandi

    Sodium

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-14149.

    Protein family/group databases

    TCDBi3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    V-type sodium ATPase subunit D
    Alternative name(s):
    Na(+)-translocating ATPase subunit D
    V-type sodium pump subunit D
    Gene namesi
    Name:ntpD
    Ordered Locus Names:EHR_08270
    OrganismiEnterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
    Taxonomic identifieri768486 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
    ProteomesiUP000002895: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 210210V-type sodium ATPase subunit DPRO_0000144275Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-59796N.

    Structurei

    Secondary structure

    1
    210
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi9 – 6961
    Helixi74 – 818
    Beta strandi89 – 979
    Beta strandi100 – 1089
    Helixi111 – 1133
    Helixi127 – 17246
    Helixi174 – 19320

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3AONX-ray2.00A1-210[»]
    3VR4X-ray2.17G1-210[»]
    3VR5X-ray3.90G1-210[»]
    3VR6X-ray2.68G1-210[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the V-ATPase D subunit family.Curated

    Phylogenomic databases

    KOiK02120.

    Family and domain databases

    HAMAPiMF_00271. ATP_synth_D_arch.
    InterProiIPR002699. V_ATPase_D.
    [Graphical view]
    PANTHERiPTHR11671. PTHR11671. 1 hit.
    PfamiPF01813. ATP-synt_D. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00309. V_ATPase_subD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P43435-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRLNVNPTRM ELTRLKKQLT TATRGHKLLK DKQDELMRQF ILLIRKNNEL    50
    RQAIEKETQT AMKDFVLAKS TVEEAFIDEL LALPAENVSI SVVEKNIMSV 100
    KVPLMNFQYD ETLNETPLEY GYLHSNAELD RSIDGFTQLL PKLLKLAEVE 150
    KTCQLMAEEI EKTRRRVNAL EYMTIPQLEE TIYYIKMKLE ENERAEVTRL 200
    IKVKNMGTEE 210
    Length:210
    Mass (Da):24,566
    Last modified:January 9, 2013 - v2
    Checksum:i6779016F1921BC85
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti201 – 21010IKVKNMGTEE → SQSEKYGNRRVRLIQFSILM AFFMIRTNRI in BAA04277. (PubMed:8157629)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D17462 Genomic DNA. Translation: BAA04277.1.
    CP003504 Genomic DNA. Translation: AFM70581.1.
    PIRiF53610.
    RefSeqiYP_006487472.1. NC_018081.1.

    Genome annotation databases

    EnsemblBacteriaiAFM70581; AFM70581; EHR_08270.
    GeneIDi13177595.
    KEGGiehr:EHR_08270.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D17462 Genomic DNA. Translation: BAA04277.1 .
    CP003504 Genomic DNA. Translation: AFM70581.1 .
    PIRi F53610.
    RefSeqi YP_006487472.1. NC_018081.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3AON X-ray 2.00 A 1-210 [» ]
    3VR4 X-ray 2.17 G 1-210 [» ]
    3VR5 X-ray 3.90 G 1-210 [» ]
    3VR6 X-ray 2.68 G 1-210 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-59796N.

    Protein family/group databases

    TCDBi 3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFM70581 ; AFM70581 ; EHR_08270 .
    GeneIDi 13177595.
    KEGGi ehr:EHR_08270.

    Phylogenomic databases

    KOi K02120.

    Enzyme and pathway databases

    BioCyci MetaCyc:MONOMER-14149.

    Family and domain databases

    HAMAPi MF_00271. ATP_synth_D_arch.
    InterProi IPR002699. V_ATPase_D.
    [Graphical view ]
    PANTHERi PTHR11671. PTHR11671. 1 hit.
    Pfami PF01813. ATP-synt_D. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00309. V_ATPase_subD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae."
      Takase K., Kakinuma S., Yamato I., Konishi K., Igarashi K., Kakinuma Y.
      J. Biol. Chem. 269:11037-11044(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-14, FUNCTION.
      Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
    2. "Genome sequence of Enterococcus hirae (Streptococcus faecalis) ATCC 9790, a model organism for the study of ion transport, bioenergetics, and copper homeostasis."
      Gaechter T., Wunderlin C., Schmidheini T., Solioz M.
      J. Bacteriol. 194:5126-5127(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.

    Entry informationi

    Entry nameiNTPD_ENTHA
    AccessioniPrimary (citable) accession number: P43435
    Secondary accession number(s): I6T729
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: January 9, 2013
    Last modified: October 1, 2014
    This is version 77 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3