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P43435

- NTPD_ENTHA

UniProt

P43435 - NTPD_ENTHA

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Protein
V-type sodium ATPase subunit D
Gene
ntpD, EHR_08270
Organism
Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in ATP-driven sodium extrusion.1 Publication

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-HAMAP

GO - Biological processi

  1. plasma membrane ATP synthesis coupled proton transport Source: UniProtKB-HAMAP
  2. sodium ion transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14149.

Protein family/group databases

TCDBi3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
V-type sodium ATPase subunit D
Alternative name(s):
Na(+)-translocating ATPase subunit D
V-type sodium pump subunit D
Gene namesi
Name:ntpD
Ordered Locus Names:EHR_08270
OrganismiEnterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)
Taxonomic identifieri768486 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
ProteomesiUP000002895: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 210210V-type sodium ATPase subunit DUniRule annotation
PRO_0000144275Add
BLAST

Interactioni

Protein-protein interaction databases

DIPiDIP-59796N.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi9 – 6961
Helixi74 – 818
Beta strandi89 – 979
Beta strandi100 – 1089
Helixi111 – 1133
Helixi127 – 17246
Helixi174 – 19320

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3AONX-ray2.00A1-210[»]
3VR4X-ray2.17G1-210[»]
3VR5X-ray3.90G1-210[»]
3VR6X-ray2.68G1-210[»]

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK02120.

Family and domain databases

HAMAPiMF_00271. ATP_synth_D_arch.
InterProiIPR002699. V_ATPase_D.
[Graphical view]
PANTHERiPTHR11671. PTHR11671. 1 hit.
PfamiPF01813. ATP-synt_D. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00309. V_ATPase_subD. 1 hit.

Sequencei

Sequence statusi: Complete.

P43435-1 [UniParc]FASTAAdd to Basket

« Hide

MRLNVNPTRM ELTRLKKQLT TATRGHKLLK DKQDELMRQF ILLIRKNNEL    50
RQAIEKETQT AMKDFVLAKS TVEEAFIDEL LALPAENVSI SVVEKNIMSV 100
KVPLMNFQYD ETLNETPLEY GYLHSNAELD RSIDGFTQLL PKLLKLAEVE 150
KTCQLMAEEI EKTRRRVNAL EYMTIPQLEE TIYYIKMKLE ENERAEVTRL 200
IKVKNMGTEE 210
Length:210
Mass (Da):24,566
Last modified:January 9, 2013 - v2
Checksum:i6779016F1921BC85
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti201 – 21010IKVKNMGTEE → SQSEKYGNRRVRLIQFSILM AFFMIRTNRI in BAA04277. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D17462 Genomic DNA. Translation: BAA04277.1.
CP003504 Genomic DNA. Translation: AFM70581.1.
PIRiF53610.
RefSeqiYP_006487472.1. NC_018081.1.

Genome annotation databases

EnsemblBacteriaiAFM70581; AFM70581; EHR_08270.
GeneIDi13177595.
KEGGiehr:EHR_08270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D17462 Genomic DNA. Translation: BAA04277.1 .
CP003504 Genomic DNA. Translation: AFM70581.1 .
PIRi F53610.
RefSeqi YP_006487472.1. NC_018081.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3AON X-ray 2.00 A 1-210 [» ]
3VR4 X-ray 2.17 G 1-210 [» ]
3VR5 X-ray 3.90 G 1-210 [» ]
3VR6 X-ray 2.68 G 1-210 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-59796N.

Protein family/group databases

TCDBi 3.A.2.2.2. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFM70581 ; AFM70581 ; EHR_08270 .
GeneIDi 13177595.
KEGGi ehr:EHR_08270.

Phylogenomic databases

KOi K02120.

Enzyme and pathway databases

BioCyci MetaCyc:MONOMER-14149.

Family and domain databases

HAMAPi MF_00271. ATP_synth_D_arch.
InterProi IPR002699. V_ATPase_D.
[Graphical view ]
PANTHERi PTHR11671. PTHR11671. 1 hit.
Pfami PF01813. ATP-synt_D. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00309. V_ATPase_subD. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae."
    Takase K., Kakinuma S., Yamato I., Konishi K., Igarashi K., Kakinuma Y.
    J. Biol. Chem. 269:11037-11044(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-14, FUNCTION.
    Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
  2. "Genome sequence of Enterococcus hirae (Streptococcus faecalis) ATCC 9790, a model organism for the study of ion transport, bioenergetics, and copper homeostasis."
    Gaechter T., Wunderlin C., Schmidheini T., Solioz M.
    J. Bacteriol. 194:5126-5127(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.

Entry informationi

Entry nameiNTPD_ENTHA
AccessioniPrimary (citable) accession number: P43435
Secondary accession number(s): I6T729
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 9, 2013
Last modified: April 16, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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