V-type sodium ATPase subunit D - Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)

Preferred order of sections

Names and origin

Protein names

Recommended name:
V-type sodium ATPase subunit D

Alternative name(s):
Na(+)-translocating ATPase subunit D
V-type sodium pump subunit D

Gene names

Name:	ntpD
Ordered Locus Names:	EHR_08270

Organism

Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258) [Complete proteome] [HAMAP]

Taxonomic identifier

768486 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacilli › Lactobacillales › Enterococcaceae › Enterococcus ›

Protein attributes

Sequence length	210 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Involved in ATP-driven sodium extrusion. Ref.1
Sequence similarities	Belongs to the V-ATPase D subunit family.

Ontologies

Keywords
Biological process	Ion transport Sodium transport Transport
Ligand	Sodium
Technical term	3D-structure Complete proteome Direct protein sequencing
Gene Ontology (GO)
Biological_process	plasma membrane ATP synthesis coupled proton transport Inferred from electronic annotation. Source: HAMAP sodium ion transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP proton-transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 210

210

V-type sodium ATPase subunit D HAMAP-Rule MF_00271

PRO_0000144275

Experimental info

Sequence conflict

201 – 210

10

IKVKNMGTEE → SQSEKYGNRRVRLIQFSILM AFFMIRTNRI in BAA04277. Ref.1

Secondary structure

1

.

210

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

P43435 [UniParc].

Last modified January 9, 2013. Version 2.
Checksum: 6779016F1921BC85
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FASTA

210

24,566

        10         20         30         40         50         60 
MRLNVNPTRM ELTRLKKQLT TATRGHKLLK DKQDELMRQF ILLIRKNNEL RQAIEKETQT 

        70         80         90        100        110        120 
AMKDFVLAKS TVEEAFIDEL LALPAENVSI SVVEKNIMSV KVPLMNFQYD ETLNETPLEY 

       130        140        150        160        170        180 
GYLHSNAELD RSIDGFTQLL PKLLKLAEVE KTCQLMAEEI EKTRRRVNAL EYMTIPQLEE 

       190        200        210 
TIYYIKMKLE ENERAEVTRL IKVKNMGTEE

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae." Takase K., Kakinuma S., Yamato I., Konishi K., Igarashi K., Kakinuma Y. J. Biol. Chem. 269:11037-11044(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-14, FUNCTION. Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
[2]	"Genome sequence of Enterococcus hirae (Streptococcus faecalis) ATCC 9790, a model organism for the study of ion transport, bioenergetics, and copper homeostasis." Gaechter T., Wunderlin C., Schmidheini T., Solioz M. J. Bacteriol. 194:5126-5127(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

D17462 Genomic DNA. Translation: BAA04277.1.
CP003504 Genomic DNA. Translation: AFM70581.1.

PIR

F53610.

RefSeq

YP_006487472.1. NC_018081.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3AON	X-ray	2.00	A	1-210	[»]
3VR4	X-ray	2.17	G	1-210	[»]
3VR5	X-ray	3.90	G	1-210	[»]
3VR6	X-ray	2.68	G	1-210	[»]

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-59796N.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

13177595.

KEGG

ehr:EHR_08270.

Organism-specific databases

CMR

Search...

Phylogenomic databases

KO

K02120.

Enzyme and pathway databases

BioCyc

MetaCyc:MONOMER-14149.

Family and domain databases

HAMAP

MF_00271. ATP_synth_D_arch.

InterPro

IPR002699. V_ATPase_D.
[Graphical view]

PANTHER

PTHR11671. PTHR11671. 1 hit.

Pfam

PF01813. ATP-synt_D. 1 hit.
[Graphical view]

TIGRFAMs

TIGR00309. V_ATPase_subD. 1 hit.

ProtoNet

Search...

Entry information

Entry name

NTPD_ENTHA

Accession

Primary (citable) accession number: P43435
Secondary accession number(s): I6T729

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	January 9, 2013
Last modified:	May 1, 2013
This is version 69 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families