P43392 (MT1A_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Metallothionein-like protein 1A
Short name=MT-1A

Alternative name(s):
MT-2
MT-Q

Gene names

Name:	MT1A
Ordered Locus Names:	At1g07600
ORF Names:	F22G5_33, F24B9.34

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	45 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence similarities	Belongs to the metallothionein superfamily. Type 15 family.

Ontologies

Keywords
Ligand	Metal-binding Metal-thiolate cluster
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	response to copper ion Inferred from expression pattern PubMed 8061521. Source: TAIR response to high light intensity Inferred from expression pattern PubMed 11683875. Source: TAIR
Molecular_function	copper ion binding Inferred from direct assay PubMed 9112777. Source: TAIR
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 45	45	Metallothionein-like protein 1A		PRO_0000197419

Sequences

	Sequence		Length	Mass (Da)
	P43392 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: B8AD2C9A030325D2	FASTA	45	4,580
	10 20 30 40 MADSNCGCGS SCKCGDSCSC EKNYNKECDN CSCGSNCSCG SNCNC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Transcripts of metallothionein genes in Arabidopsis thaliana." Yeh S.C., Hsieh H.M., Huang P.C. DNA Seq. 5:141-144(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia.
[2]	"Structure, organization and expression of the metallothionein gene family in Arabidopsis." Zhou J., Goldsbrough P.B. Mol. Gen. Genet. 248:318-328(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. Columbia.
[3]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[4]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[5]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[6]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U15130 mRNA. Translation: AAA50251.1. U11253 Genomic DNA. Translation: AAA82209.1. AC007583 Genomic DNA. Translation: AAF75098.1. CP002684 Genomic DNA. Translation: AEE28147.1. AF332449 mRNA. Translation: AAG48812.1. AF386921 mRNA. Translation: AAK62366.1. AY128916 mRNA. Translation: AAM91316.1. AY086003 mRNA. Translation: AAM63212.1.
IPI	IPI00533724.
PIR	S57858.
RefSeq	NP_172239.1. NM_100633.2.
UniGene	At.23699. At.48120.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	3702.AT1G07600.1-P.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G07600.1; AT1G07600.1; AT1G07600.
GeneID	837273.
KEGG	ath:AT1G07600.
Organism-specific databases
TAIR	At1g07600.
Phylogenomic databases
HOGENOM	HOG000113674.
ProtClustDB	CLSN2913567.
Gene expression databases
ArrayExpress	P43392.
Genevestigator	P43392.
GermOnline	AT1G07600. Arabidopsis thaliana.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

MT1A_ARATH

Accession

Primary (citable) accession number: P43392

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program