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Protein

Translationally-controlled tumor protein homolog

Gene

TPT1

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in calcium binding and microtubule stabilization.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalcium

Names & Taxonomyi

Protein namesi
Recommended name:
Translationally-controlled tumor protein homolog
Short name:
TCTP
Alternative name(s):
p23
pCHK23
Gene namesi
Name:TPT1
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002112731 – 172Translationally-controlled tumor protein homologAdd BLAST172

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei46Phosphoserine; by PLK1By similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP43347
PRIDEiP43347

Expressioni

Gene expression databases

BgeeiENSGALG00000028872

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi676616, 1 interactor
STRINGi9031.ENSGALP00000035709

Structurei

3D structure databases

ProteinModelPortaliP43347
SMRiP43347
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 172TCTPPROSITE-ProRule annotationAdd BLAST172

Sequence similaritiesi

Belongs to the TCTP family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1727 Eukaryota
ENOG4111FVP LUCA
GeneTreeiENSGT00390000006051
HOGENOMiHOG000203361
HOVERGENiHBG002282
InParanoidiP43347
OMAiFKDFEFY
OrthoDBiEOG091G0OTA
PhylomeDBiP43347
TreeFamiTF300238

Family and domain databases

Gene3Di2.170.150.10, 1 hit
InterProiView protein in InterPro
IPR011057 Mss4-like_sf
IPR011323 Mss4/transl-control_tumor
IPR034737 TCTP
IPR018103 Translation_control_tumour_CS
IPR018105 Translational_control_tumour_p
PANTHERiPTHR11991 PTHR11991, 1 hit
PfamiView protein in Pfam
PF00838 TCTP, 1 hit
PRINTSiPR01653 TCTPROTEIN
SUPFAMiSSF51316 SSF51316, 1 hit
PROSITEiView protein in PROSITE
PS01002 TCTP_1, 1 hit
PS01003 TCTP_2, 1 hit
PS51797 TCTP_3, 1 hit

Sequencei

Sequence statusi: Complete.

P43347-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIYRDCISQ DEMFSDIYKI REVANGLCLE VEGKMVTRTE GQIDDSLIGG
60 70 80 90 100
NASAEGPEGE GTEATVITGV DIVINHHLQE TSFTKESYKK YIKDYMKAIK
110 120 130 140 150
ARLEEHKPER VKPFMTGAAE QIKHILANFK NYQFFVGENM NPDGMVALLD
160 170
FREDGVTPYM IFFKDGLEIE KC
Length:172
Mass (Da):19,530
Last modified:November 1, 1995 - v1
Checksum:i3D3DB669AC8E58F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U25954 mRNA Translation: AAA67296.1
D26312 mRNA Translation: BAA05374.1
PIRiA38960
RefSeqiNP_990729.1, NM_205398.1
UniGeneiGga.4312

Genome annotation databases

EnsembliENSGALT00000044027; ENSGALP00000042618; ENSGALG00000028872
GeneIDi396363
KEGGigga:396363

Similar proteinsi

Entry informationi

Entry nameiTCTP_CHICK
AccessioniPrimary (citable) accession number: P43347
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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