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P43304

- GPDM_HUMAN

UniProt

P43304 - GPDM_HUMAN

Protein

Glycerol-3-phosphate dehydrogenase, mitochondrial

Gene

GPD2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 143 (01 Oct 2014)
      Sequence version 3 (05 May 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

    Cofactori

    FAD.

    Enzyme regulationi

    Calcium-binding enhance the activity of the enzyme.

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi71 – 9929FADSequence AnalysisAdd
    BLAST
    Calcium bindingi672 – 68312PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. calcium ion binding Source: ProtInc
    2. glycerol-3-phosphate dehydrogenase activity Source: ProtInc
    3. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

    GO - Biological processi

    1. camera-type eye development Source: Ensembl
    2. cellular lipid metabolic process Source: Reactome
    3. gluconeogenesis Source: Ensembl
    4. glycerol-3-phosphate metabolic process Source: Ensembl
    5. glycerol catabolic process Source: UniProtKB-UniPathway
    6. multicellular organism growth Source: Ensembl
    7. small molecule metabolic process Source: Reactome

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    Calcium, FAD, Flavoprotein, Metal-binding

    Enzyme and pathway databases

    BioCyciMetaCyc:HS03841-MONOMER.
    ReactomeiREACT_22279. Fatty acid, triacylglycerol, and ketone body metabolism.
    UniPathwayiUPA00618; UER00673.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycerol-3-phosphate dehydrogenase, mitochondrial (EC:1.1.5.3)
    Short name:
    GPD-M
    Short name:
    GPDH-M
    Alternative name(s):
    mtGPD
    Gene namesi
    Name:GPD2
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:4456. GPD2.

    Subcellular locationi

    GO - Cellular componenti

    1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
    2. mitochondrial inner membrane Source: Reactome

    Keywords - Cellular componenti

    Mitochondrion

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA28837.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 4242MitochondrionBy similarityAdd
    BLAST
    Chaini43 – 727685Glycerol-3-phosphate dehydrogenase, mitochondrialPRO_0000010429Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei601 – 6011PhosphotyrosineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiP43304.
    PaxDbiP43304.
    PRIDEiP43304.

    2D gel databases

    REPRODUCTION-2DPAGEIPI00017895.
    UCD-2DPAGEP43304.

    PTM databases

    PhosphoSiteiP43304.

    Expressioni

    Gene expression databases

    ArrayExpressiP43304.
    BgeeiP43304.
    CleanExiHS_GPD2.
    GenevestigatoriP43304.

    Organism-specific databases

    HPAiHPA008012.

    Interactioni

    Protein-protein interaction databases

    BioGridi109081. 4 interactions.
    IntActiP43304. 1 interaction.
    MINTiMINT-4530883.
    STRINGi9606.ENSP00000308610.

    Structurei

    3D structure databases

    ProteinModelPortaliP43304.
    SMRiP43304. Positions 63-693.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini623 – 65836EF-hand 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini659 – 69436EF-hand 2PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 2 EF-hand domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Transit peptide

    Phylogenomic databases

    eggNOGiCOG0578.
    HOGENOMiHOG000004813.
    HOVERGENiHBG005897.
    InParanoidiP43304.
    KOiK00111.
    OMAiKHLTESY.
    OrthoDBiEOG74TWZ2.
    PhylomeDBiP43304.
    TreeFamiTF300359.

    Family and domain databases

    Gene3Di1.10.238.10. 1 hit.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR006076. FAD-dep_OxRdtase.
    IPR000447. G3P_DH_FAD-dep.
    [Graphical view]
    PfamiPF01266. DAO. 1 hit.
    PF13499. EF-hand_7. 1 hit.
    [Graphical view]
    PRINTSiPR01001. FADG3PDH.
    SMARTiSM00054. EFh. 2 hits.
    [Graphical view]
    PROSITEiPS00018. EF_HAND_1. 1 hit.
    PS50222. EF_HAND_2. 2 hits.
    PS00977. FAD_G3PDH_1. 1 hit.
    PS00978. FAD_G3PDH_2. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: P43304-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MAFQKAVKGT ILVGGGALAT VLGLSQFAHY RRKQMNLAYV KAADCISEPV    50
    NREPPSREAQ LLTLQNTSEF DILVIGGGAT GSGCALDAVT RGLKTALVER 100
    DDFSSGTSSR STKLIHGGVR YLQKAIMKLD IEQYRMVKEA LHERANLLEI 150
    APHLSAPLPI MLPVYKWWQL PYYWVGIKLY DLVAGSNCLK SSYVLSKSRA 200
    LEHFPMLQKD KLVGAIVYYD GQHNDARMNL AIALTAARYG AATANYMEVV 250
    SLLKKTDPQT GKVRVSGARC KDVLTGQEFD VRAKCVINAT GPFTDSVRKM 300
    DDKDAAAICQ PSAGVHIVMP GYYSPESMGL LDPATSDGRV IFFLPWQKMT 350
    IAGTTDTPTD VTHHPIPSEE DINFILNEVR NYLSCDVEVR RGDVLAAWSG 400
    IRPLVTDPKS ADTQSISRNH VVDISESGLI TIAGGKWTTY RSMAEDTINA 450
    AVKTHNLKAG PSRTVGLFLQ GGKDWSPTLY IRLVQDYGLE SEVAQHLAAT 500
    YGDKAFEVAK MASVTGKRWP IVGVRLVSEF PYIEAEVKYG IKEYACTAVD 550
    MISRRTRLAF LNVQAAEEAL PRIVELMGRE LNWDDYKKQE QLETARKFLY 600
    YEMGYKSRSE QLTDRSEISL LPSDIDRYKK RFHKFDADQK GFITIVDVQR 650
    VLESINVQMD ENTLHEILNE VDLNKNGQVE LNEFLQLMSA IQKGRVSGSR 700
    LAILMKTAEE NLDRRVPIPV DRSCGGL 727
    Length:727
    Mass (Da):80,853
    Last modified:May 5, 2009 - v3
    Checksum:i70D8B4E5CB4F2EFD
    GO
    Isoform 2 (identifier: P43304-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-126: Missing.

    Show »
    Length:601
    Mass (Da):67,531
    Checksum:i1953A7AC32B5DF02
    GO

    Sequence cautioni

    The sequence BAD92636.1 differs from that shown. Reason: Erroneous initiation.

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti264 – 2641R → H.8 Publications
    Corresponds to variant rs2116665 [ dbSNP | Ensembl ].
    VAR_049113
    Natural varianti453 – 4531K → Q.
    Corresponds to variant rs35096779 [ dbSNP | Ensembl ].
    VAR_049114
    Natural varianti525 – 5251R → H.2 Publications
    Corresponds to variant rs1051916 [ dbSNP | Ensembl ].
    VAR_025215

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 126126Missing in isoform 2. 2 PublicationsVSP_017134Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U12424 mRNA. Translation: AAA65701.1.
    U36310 mRNA. Translation: AAB60403.1.
    U40367
    , U40353, U40354, U40355, U40357, U40358, U40359, U40360, U40361, U40362, U40363, U40364, U40365 Genomic DNA. Translation: AAC50556.1.
    AF311325 mRNA. Translation: AAG33851.1.
    AK093198 mRNA. Translation: BAG52671.1.
    AK291065 mRNA. Translation: BAF83754.1.
    AK292817 mRNA. Translation: BAF85506.1.
    AB209399 mRNA. Translation: BAD92636.1. Different initiation.
    AC011308 Genomic DNA. No translation available.
    AC092686 Genomic DNA. No translation available.
    CH471058 Genomic DNA. Translation: EAX11453.1.
    U79250 mRNA. Translation: AAB50200.1.
    CCDSiCCDS2202.1. [P43304-1]
    PIRiG02093.
    RefSeqiNP_000399.3. NM_000408.4. [P43304-1]
    NP_001076581.2. NM_001083112.2. [P43304-1]
    XP_005246526.1. XM_005246469.1. [P43304-1]
    UniGeneiHs.512382.

    Genome annotation databases

    EnsembliENST00000310454; ENSP00000308610; ENSG00000115159. [P43304-1]
    ENST00000409674; ENSP00000386425; ENSG00000115159. [P43304-1]
    ENST00000409861; ENSP00000386626; ENSG00000115159. [P43304-1]
    ENST00000438166; ENSP00000409708; ENSG00000115159. [P43304-1]
    GeneIDi2820.
    KEGGihsa:2820.
    UCSCiuc002tzd.4. human. [P43304-1]

    Polymorphism databases

    DMDMi229462943.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U12424 mRNA. Translation: AAA65701.1 .
    U36310 mRNA. Translation: AAB60403.1 .
    U40367
    , U40353 , U40354 , U40355 , U40357 , U40358 , U40359 , U40360 , U40361 , U40362 , U40363 , U40364 , U40365 Genomic DNA. Translation: AAC50556.1 .
    AF311325 mRNA. Translation: AAG33851.1 .
    AK093198 mRNA. Translation: BAG52671.1 .
    AK291065 mRNA. Translation: BAF83754.1 .
    AK292817 mRNA. Translation: BAF85506.1 .
    AB209399 mRNA. Translation: BAD92636.1 . Different initiation.
    AC011308 Genomic DNA. No translation available.
    AC092686 Genomic DNA. No translation available.
    CH471058 Genomic DNA. Translation: EAX11453.1 .
    U79250 mRNA. Translation: AAB50200.1 .
    CCDSi CCDS2202.1. [P43304-1 ]
    PIRi G02093.
    RefSeqi NP_000399.3. NM_000408.4. [P43304-1 ]
    NP_001076581.2. NM_001083112.2. [P43304-1 ]
    XP_005246526.1. XM_005246469.1. [P43304-1 ]
    UniGenei Hs.512382.

    3D structure databases

    ProteinModelPortali P43304.
    SMRi P43304. Positions 63-693.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 109081. 4 interactions.
    IntActi P43304. 1 interaction.
    MINTi MINT-4530883.
    STRINGi 9606.ENSP00000308610.

    PTM databases

    PhosphoSitei P43304.

    Polymorphism databases

    DMDMi 229462943.

    2D gel databases

    REPRODUCTION-2DPAGE IPI00017895.
    UCD-2DPAGE P43304.

    Proteomic databases

    MaxQBi P43304.
    PaxDbi P43304.
    PRIDEi P43304.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000310454 ; ENSP00000308610 ; ENSG00000115159 . [P43304-1 ]
    ENST00000409674 ; ENSP00000386425 ; ENSG00000115159 . [P43304-1 ]
    ENST00000409861 ; ENSP00000386626 ; ENSG00000115159 . [P43304-1 ]
    ENST00000438166 ; ENSP00000409708 ; ENSG00000115159 . [P43304-1 ]
    GeneIDi 2820.
    KEGGi hsa:2820.
    UCSCi uc002tzd.4. human. [P43304-1 ]

    Organism-specific databases

    CTDi 2820.
    GeneCardsi GC02P157291.
    H-InvDB HIX0002519.
    HGNCi HGNC:4456. GPD2.
    HPAi HPA008012.
    MIMi 138430. gene.
    neXtProti NX_P43304.
    PharmGKBi PA28837.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG0578.
    HOGENOMi HOG000004813.
    HOVERGENi HBG005897.
    InParanoidi P43304.
    KOi K00111.
    OMAi KHLTESY.
    OrthoDBi EOG74TWZ2.
    PhylomeDBi P43304.
    TreeFami TF300359.

    Enzyme and pathway databases

    UniPathwayi UPA00618 ; UER00673 .
    BioCyci MetaCyc:HS03841-MONOMER.
    Reactomei REACT_22279. Fatty acid, triacylglycerol, and ketone body metabolism.

    Miscellaneous databases

    GenomeRNAii 2820.
    NextBioi 11111.
    PROi P43304.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P43304.
    Bgeei P43304.
    CleanExi HS_GPD2.
    Genevestigatori P43304.

    Family and domain databases

    Gene3Di 1.10.238.10. 1 hit.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR006076. FAD-dep_OxRdtase.
    IPR000447. G3P_DH_FAD-dep.
    [Graphical view ]
    Pfami PF01266. DAO. 1 hit.
    PF13499. EF-hand_7. 1 hit.
    [Graphical view ]
    PRINTSi PR01001. FADG3PDH.
    SMARTi SM00054. EFh. 2 hits.
    [Graphical view ]
    PROSITEi PS00018. EF_HAND_1. 1 hit.
    PS50222. EF_HAND_2. 2 hits.
    PS00977. FAD_G3PDH_1. 1 hit.
    PS00978. FAD_G3PDH_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence of a human mitochondrial glycerol-3-phosphate dehydrogenase-encoding cDNA."
      Lehn D.A., Brown L.J., Simonson G.D., Moran S.M., McDonald M.J.
      Gene 150:417-418(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANTS HIS-264 AND HIS-525.
    2. "Mitochondrial glycerol-3-phosphate dehydrogenase. Cloning of an alternatively spliced human islet-cell cDNA, tissue distribution, physical mapping, and identification of a polymorphic genetic marker."
      Ferrer J., Aoki M., Behn P., Nestorowicz A., Riggs A., Permutt M.A.
      Diabetes 45:262-266(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT HIS-264.
    3. "Structural organization and mapping of the human mitochondrial glycerol phosphate dehydrogenase-encoding gene and pseudogene."
      Brown L.J., Stoffel M., Moran S.M., Fernald A.A., Lehn D.A., LeBeau M.M., MacDonald M.J.
      Gene 172:309-312(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT HIS-264.
    4. "A novel glycerol-3-phosphate dehydrogenase 3 from adult testis."
      Yin L.L., Li J.M., Sha J.H.
      Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANTS HIS-264 AND HIS-525.
      Tissue: Testis.
    5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT HIS-264.
      Tissue: Testis and Trachea.
    6. Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT HIS-264.
      Tissue: Brain.
    7. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT HIS-264.
    9. "Large-scale concatenation cDNA sequencing."
      Yu W., Andersson B., Worley K.C., Muzny D.M., Ding Y., Liu W., Ricafrente J.Y., Wentland M.A., Lennon G., Gibbs R.A.
      Genome Res. 7:353-358(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-408, VARIANT HIS-264.
      Tissue: Brain.
    10. Lubec G., Afjehi-Sadat L.
      Submitted (MAR-2007) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 212-227 AND 558-572, IDENTIFICATION BY MASS SPECTROMETRY.
      Tissue: Brain and Cajal-Retzius cell.
    11. Bienvenut W.V., Claeys D.
      Submitted (JAN-2006) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 340-348; 410-418; 526-538; 558-572 AND 715-722, IDENTIFICATION BY MASS SPECTROMETRY.
      Tissue: Platelet.
    12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiGPDM_HUMAN
    AccessioniPrimary (citable) accession number: P43304
    Secondary accession number(s): A8K4V0
    , B3KSA9, Q59FR1, Q9HAP9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 143 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 2
      Human chromosome 2: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3