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Protein

Probable cysteine protease RD19B

Gene

RD19B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probable thiol protease.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei156PROSITE-ProRule annotation1
Active sitei299PROSITE-ProRule annotation1
Active sitei326PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol protease

Enzyme and pathway databases

ReactomeiR-ATH-114608. Platelet degranulation.
R-ATH-2132295. MHC class II antigen presentation.

Protein family/group databases

MEROPSiC01.A04.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cysteine protease RD19BCurated (EC:3.4.22.-)
Alternative name(s):
RD19-like protein 11 Publication
Thiol protease A14941 Publication
Gene namesi
Name:RD19BCurated
Synonyms:RDL11 Publication
Ordered Locus Names:At2g21430
ORF Names:F3K23.19
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G21430.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
PropeptideiPRO_000002645325 – 131Activation peptideCuratedAdd BLAST107
ChainiPRO_0000026454132 – 361Probable cysteine protease RD19BAdd BLAST230

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi153 ↔ 203By similarity
Disulfide bondi187 ↔ 237By similarity
Glycosylationi250N-linked (GlcNAc...)PROSITE-ProRule annotation1
Disulfide bondi293 ↔ 347By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, Zymogen

Proteomic databases

PaxDbiP43295.

Expressioni

Inductioni

By wilting and abscisic acid (ABA) (PubMed:8018874). Induced by drought stress (PubMed:12102506).2 Publications

Gene expression databases

ExpressionAtlasiP43295. baseline and differential.
GenevisibleiP43295. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G21430.1.

Structurei

3D structure databases

ProteinModelPortaliP43295.
SMRiP43295.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C1 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1542. Eukaryota.
COG4870. LUCA.
HOGENOMiHOG000230774.
InParanoidiP43295.
KOiK01373.
OMAiGSIEEHY.
OrthoDBiEOG09360CFD.
PhylomeDBiP43295.

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43295-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDYHLRVLFS VSLIFVFVSV SVCGDEDVLI RQVVDETEPK VLSSEDHFTL
60 70 80 90 100
FKKKFGKVYG SIEEHYYRFS VFKANLLRAM RHQKMDPSAR HGVTQFSDLT
110 120 130 140 150
RSEFRRKHLG VKGGFKLPKD ANQAPILPTQ NLPEEFDWRD RGAVTPVKNQ
160 170 180 190 200
GSCGSCWSFS TTGALEGAHF LATGKLVSLS EQQLVDCDHE CDPEEEGSCD
210 220 230 240 250
SGCNGGLMNS AFEYTLKTGG LMREKDYPYT GTDGGSCKLD RSKIVASVSN
260 270 280 290 300
FSVVSINEDQ IAANLIKNGP LAVAINAAYM QTYIGGVSCP YICSRRLNHG
310 320 330 340 350
VLLVGYGSAG FSQARLKEKP YWIIKNSWGE SWGENGFYKI CKGRNICGVD
360
SLVSTVAATT S
Length:361
Mass (Da):39,819
Last modified:December 8, 2000 - v2
Checksum:iD09A2CE5654642DD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti49T → A in CAA52403 (PubMed:8018874).Curated1
Sequence conflicti206G → R in BAD43619 (Ref. 3) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006841 Genomic DNA. Translation: AAD23687.1.
CP002685 Genomic DNA. Translation: AEC07177.1.
AK175856 mRNA. Translation: BAD43619.1.
BT029231 mRNA. Translation: ABJ98563.1.
X74359 mRNA. Translation: CAA52403.1.
PIRiB84601.
RefSeqiNP_565512.1. NM_127715.4.
UniGeneiAt.14069.

Genome annotation databases

EnsemblPlantsiAT2G21430.1; AT2G21430.1; AT2G21430.
GeneIDi816682.
GrameneiAT2G21430.1; AT2G21430.1; AT2G21430.
KEGGiath:AT2G21430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006841 Genomic DNA. Translation: AAD23687.1.
CP002685 Genomic DNA. Translation: AEC07177.1.
AK175856 mRNA. Translation: BAD43619.1.
BT029231 mRNA. Translation: ABJ98563.1.
X74359 mRNA. Translation: CAA52403.1.
PIRiB84601.
RefSeqiNP_565512.1. NM_127715.4.
UniGeneiAt.14069.

3D structure databases

ProteinModelPortaliP43295.
SMRiP43295.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G21430.1.

Protein family/group databases

MEROPSiC01.A04.

Proteomic databases

PaxDbiP43295.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G21430.1; AT2G21430.1; AT2G21430.
GeneIDi816682.
GrameneiAT2G21430.1; AT2G21430.1; AT2G21430.
KEGGiath:AT2G21430.

Organism-specific databases

TAIRiAT2G21430.

Phylogenomic databases

eggNOGiKOG1542. Eukaryota.
COG4870. LUCA.
HOGENOMiHOG000230774.
InParanoidiP43295.
KOiK01373.
OMAiGSIEEHY.
OrthoDBiEOG09360CFD.
PhylomeDBiP43295.

Enzyme and pathway databases

ReactomeiR-ATH-114608. Platelet degranulation.
R-ATH-2132295. MHC class II antigen presentation.

Miscellaneous databases

PROiP43295.

Gene expression databases

ExpressionAtlasiP43295. baseline and differential.
GenevisibleiP43295. AT.

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRD19B_ARATH
AccessioniPrimary (citable) accession number: P43295
Secondary accession number(s): Q058I7, Q680L1, Q9SJT5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: December 8, 2000
Last modified: November 30, 2016
This is version 121 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.