P43237 (ALL11_ARAHY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Allergen Ara h 1, clone P17 Alternative name(s): Allergen Ara h I Allergen=Ara h 1
Organism	Arachis hypogaea (Peanut)
Taxonomic identifier	3818 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fabales › Fabaceae › Papilionoideae › Dalbergieae › Arachis

Protein attributes

Sequence length	614 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Allergenic properties	Causes an allergic reaction in human.
Sequence similarities	Belongs to the 7S seed storage protein family.

Ontologies

Keywords
Disease	Allergen
Domain	Signal
PTM	Glycoprotein
Gene Ontology (GO)
Molecular function	nutrient reservoir activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential
	Chain	26 – 614	589	Allergen Ara h 1, clone P17		PRO_0000032196
Amino acid modifications
	Glycosylation	516	1	N-linked (GlcNAc...) Ref.2		CAR_000218

Sequences

	Sequence		Length	Mass (Da)
	P43237 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 1DDACF217EEC5F31	FASTA	614	70,283
	10 20 30 40 50 60 MRGRVSPLML LLGILVLASV SATQAKSPYR KTENPCAQRC LQSCQQEPDD LKQKACESRC 70 80 90 100 110 120 TKLEYDPRCV YDTGATNQRH PPGERTRGRQ PGDYDDDRRQ PRREEGGRWG PAEPRERERE 130 140 150 160 170 180 EDWRQPREDW RRPSHQQPRK IRPEGREGEQ EWGTPGSEVR EETSRNNPFY FPSRRFSTRY 190 200 210 220 230 240 GNQNGRIRVL QRFDQRSKQF QNLQNHRIVQ IEARPNTLVL PKHADADNIL VIQQGQATVT 250 260 270 280 290 300 VANGNNRKSF NLDEGHALRI PSGFISYILN RHDNQNLRVA KISMPVNTPG QFEDFFPASS 310 320 330 340 350 360 RDQSSYLQGF SRNTLEAAFN AEFNEIRRVL LEENAGGEQE ERGQRRRSTR SSDNEGVIVK 370 380 390 400 410 420 VSKEHVQELT KHAKSVSKKG SEEEDITNPI NLRDGEPDLS NNFGRLFEVK PDKKNPQLQD 430 440 450 460 470 480 LDMMLTCVEI KEGALMLPHF NSKAMVIVVV NKGTGNLELV AVRKEQQQRG RREQEWEEEE 490 500 510 520 530 540 EDEEEEGSNR EVRRYTARLK EGDVFIMPAA HPVAINASSE LHLLGFGINA ENNHRIFLAG 550 560 570 580 590 600 DKDNVIDQIE KQAKDLAFPG SGEQVEKLIK NQRESHFVSA RPQSQSPSSP EKEDQEEENQ 610 GGKGPLLSIL KAFN

References

[1]	"Recombinant peanut allergen Ara h I expression and IgE binding in patients with peanut hypersensitivity." Burks A.W., Cockrell G., Stanley J.S., Helm R.M., Bannon G.A. J. Clin. Invest. 96:1715-1721(1995) [PubMed: 7560062] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Florunner.
[2]	"N-glycan analysis by matrix-assisted laser desorption/ionization mass spectrometry of electrophoretically separated nonmammalian proteins: application to peanut allergen Ara h 1 and olive pollen allergen Ole e 1." Kolarich D., Altmann F. Anal. Biochem. 285:64-75(2000) [PubMed: 10998264] [Abstract] Cited for: GLYCOSYLATION AT ASN-516.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L38853 mRNA. Translation: AAA60336.1.
3D structure databases
ProteinModelPortal	P43237.
ModBase	Search...
Protein-protein interaction databases
IntAct	P43237. 5 interactions.
Protein family/group databases
Allergome	50. Ara h 1.
PTM databases
GlycoSuiteDB	P43237.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR006045. Cupin_1. IPR011051. Cupin_RmlC_type. IPR014710. RmlC-like_jellyroll. [Graphical view]
Gene3D	G3DSA:2.60.120.10. RmlC-like_jellyroll. 2 hits.
Pfam	PF00190. Cupin_1. 2 hits. [Graphical view]
SMART	SM00835. Cupin_1. 2 hits. [Graphical view]
SUPFAM	SSF51182. RmlC_like_cupin. 2 hits.
ProtoNet	Search...

Entry information

Entry name

ALL11_ARAHY

Accession

Primary (citable) accession number: P43237

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	September 21, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program