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Protein

Probable non-specific lipid-transfer protein

Gene

PMAI

Organism
Parietaria judaica (Pellitory-of-the-wall) (Parietaria diffusa)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport
LigandLipid-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable non-specific lipid-transfer protein
Short name:
LTP
Alternative name(s):
Allergen Par j I
Major pollen allergen Par j 1.0101
Protein P5
Allergen: Par j 1.0101
Gene namesi
Name:PMAI
OrganismiParietaria judaica (Pellitory-of-the-wall) (Parietaria diffusa)
Taxonomic identifieri33127 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesUrticaceaeParietaria

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Binds to IgE and induces histamine release from basophils of Pj-pollen-allergic subjects.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei503. Par j 1.
504. Par j 1.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000153874‹1 – 139Probable non-specific lipid-transfer proteinAdd BLAST›139

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi14 ↔ 29By similarity
Disulfide bondi30 ↔ 75By similarity
Disulfide bondi50 ↔ 91By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliP43217.
SMRiP43217.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the plant LTP family.Curated

Family and domain databases

InterProiView protein in InterPro
IPR016140. Bifunc_inhib/LTP/seed_store.
IPR000528. Plant_LTP.
PfamiView protein in Pfam
PF00234. Tryp_alpha_amyl. 1 hit.
PRINTSiPR00382. LIPIDTRNSFER.
SMARTiView protein in SMART
SM00499. AAI. 1 hit.
SUPFAMiSSF47699. SSF47699. 1 hit.
PROSITEiView protein in PROSITE
PS00597. PLANT_LTP. 1 hit.

Sequencei

Sequence statusi: Fragment.

P43217-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QETCGTMVRA LMPCLPFVQG KEKEPSKGCC SGAKRLDGET KTGPQRVHAC
60 70 80 90 100
ECIQTAMKTY SDIDGKLVSE VPKHCGIVDS KLPPIDVNMD CKTVGVVPRQ
110 120 130
PQLPVSLRHG PVTGPSDPAH KARLERPQIR VPPPAPEKA
Length:139
Mass (Da):14,986
Last modified:December 15, 1998 - v3
Checksum:i36C3544DD699D6C7
GO

Sequence cautioni

The sequence CAA54587 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77414 mRNA. Translation: CAA54587.1. Different initiation.
PIRiS77948.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiNLT11_PARJU
AccessioniPrimary (citable) accession number: P43217
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: December 15, 1998
Last modified: March 15, 2017
This is version 69 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families