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Protein

Pollen allergen Phl p 6

Gene

PHLPVI

Organism
Phleum pratense (Common timothy)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Pollen allergen Phl p 6
Alternative name(s):
Allergen Phl p VI
Allergen: Phl p 6
Gene namesi
Name:PHLPVI
OrganismiPhleum pratense (Common timothy)
Taxonomic identifieri15957 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaePoodaePoeaePoeae Chloroplast Group 2 (Poeae type)PoinaePhleum

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3420. Phl p 6.0101.
569. Phl p 6.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 132110Pollen allergen Phl p 6PRO_0000021750Add
BLAST

Structurei

Secondary structure

1
132
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi26 – 4621Combined sources
Turni47 – 493Combined sources
Helixi52 – 7726Combined sources
Helixi81 – 9717Combined sources
Turni101 – 1033Combined sources
Helixi104 – 12017Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1NLXX-ray2.80A/B/C/D/E/F/G/H/I/J/K/L/M/N23-132[»]
ProteinModelPortaliP43215.
SMRiP43215. Positions 25-128.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP43215.

Family & Domainsi

Sequence similaritiesi

Belongs to the Poa p IX/Phl p VI allergen family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di1.20.120.320. 1 hit.
InterProiIPR002914. Poa_pIX/Phl_pVI.
[Graphical view]
PfamiPF01620. Pollen_allerg_2. 1 hit.
[Graphical view]
SUPFAMiSSF81736. SSF81736. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43215-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAMFLAVAV VLGLATSPTA EGGKATTEEQ KLIEDVNASF RAAMATTANV
60 70 80 90 100
PPADKYKTFE AAFTVSSKRN LADAVSKAPQ LVPKLDEVYN AAYNAADHAA
110 120 130
PEDKYEAFVL HFSEALRIIA GTPEVHAVKP GA
Length:132
Mass (Da):13,921
Last modified:November 1, 1995 - v1
Checksum:i3513D3D85069D5F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z27082 mRNA. Translation: CAA81608.1.
PIRiS38585.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z27082 mRNA. Translation: CAA81608.1.
PIRiS38585.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1NLXX-ray2.80A/B/C/D/E/F/G/H/I/J/K/L/M/N23-132[»]
ProteinModelPortaliP43215.
SMRiP43215. Positions 25-128.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3420. Phl p 6.0101.
569. Phl p 6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP43215.

Family and domain databases

Gene3Di1.20.120.320. 1 hit.
InterProiIPR002914. Poa_pIX/Phl_pVI.
[Graphical view]
PfamiPF01620. Pollen_allerg_2. 1 hit.
[Graphical view]
SUPFAMiSSF81736. SSF81736. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Characterization of the allergen group VI in timothy grass pollen (Phl p 6). II. cDNA cloning of Phl p 6 and structural comparison to grass group V."
    Petersen A., Bufe A., Schramm G., Schlaak M., Becker W.
    Int. Arch. Allergy Immunol. 108:55-59(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], ALLERGEN.
    Strain: cv. Agrostideae 24W28-7C.

Entry informationi

Entry nameiMPAP6_PHLPR
AccessioniPrimary (citable) accession number: P43215
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 17, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.