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Protein

Pollen allergen Phl p 2

Gene

PHLPII

Organism
Phleum pratense (Common timothy)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Pollen allergen Phl p 2
Alternative name(s):
Allergen Phl p II
Allergen: Phl p 2
Gene namesi
Name:PHLPII
OrganismiPhleum pratense (Common timothy)
Taxonomic identifieri15957 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaePoodaePoeaePoeae Chloroplast Group 2 (Poeae type)PoinaePhleum

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Causes grass pollen allergy. Binds to IgE.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3419 Phl p 2.0101
555 Phl p 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000000872327 – 122Pollen allergen Phl p 2Add BLAST96

Proteomic databases

PRIDEiP43214

Expressioni

Tissue specificityi

Pollen specific.

Structurei

Secondary structure

1122
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi29 – 34Combined sources6
Beta strandi42 – 49Combined sources8
Beta strandi50 – 52Combined sources3
Beta strandi54 – 60Combined sources7
Beta strandi62 – 66Combined sources5
Helixi74 – 76Combined sources3
Beta strandi77 – 81Combined sources5
Beta strandi88 – 96Combined sources9
Turni97 – 99Combined sources3
Beta strandi101 – 108Combined sources8
Beta strandi114 – 116Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BMWNMR-A27-122[»]
1WHOX-ray1.90A27-122[»]
1WHPX-ray3.00A27-122[»]
2VXQX-ray1.90A27-122[»]
ProteinModelPortaliP43214
SMRiP43214
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP43214

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 120Expansin-like CBDPROSITE-ProRule annotationAdd BLAST80

Sequence similaritiesi

Belongs to the expansin family. Expansin B subfamily.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.40.760, 1 hit
InterProiView protein in InterPro
IPR005453 Allergen_Lolp2
IPR007117 Expansin_CBD
IPR036749 Expansin_CBD_sf
PfamiView protein in Pfam
PF01357 Pollen_allerg_1, 1 hit
PRINTSiPR01637 LOLP2ALLERGN
SUPFAMiSSF49590 SSF49590, 1 hit
PROSITEiView protein in PROSITE
PS50843 EXPANSIN_CBD, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43214-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMASSSSSS LLAMAVLAAL FAGAWCVPKV TFTVEKGSNE KHLAVLVKYE
60 70 80 90 100
GDTMAEVELR EHGSDEWVAM TKGEGGVWTF DSEEPLQGPF NFRFLTEKGM
110 120
KNVFDDVVPE KYTIGATYAP EE
Length:122
Mass (Da):13,362
Last modified:November 1, 1995 - v1
Checksum:i708B911B25EE26F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X75925 mRNA Translation: CAA53529.1
PIRiS39457

Similar proteinsi

Entry informationi

Entry nameiMPAP2_PHLPR
AccessioniPrimary (citable) accession number: P43214
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 23, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

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