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Protein

Pollen allergen Phl p 2

Gene

PHLPII

Organism
Phleum pratense (Common timothy)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Pollen allergen Phl p 2
Alternative name(s):
Allergen Phl p II
Allergen: Phl p 2
Gene namesi
Name:PHLPII
OrganismiPhleum pratense (Common timothy)
Taxonomic identifieri15957 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaePoodaePoeaePoeae Chloroplast Group 2 (Poeae type)PoinaePhleum

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Causes grass pollen allergy. Binds to IgE.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3419. Phl p 2.0101.
555. Phl p 2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000000872327 – 122Pollen allergen Phl p 2Add BLAST96

Expressioni

Tissue specificityi

Pollen specific.

Structurei

Secondary structure

1122
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi29 – 34Combined sources6
Beta strandi42 – 49Combined sources8
Beta strandi50 – 52Combined sources3
Beta strandi54 – 60Combined sources7
Beta strandi62 – 66Combined sources5
Helixi74 – 76Combined sources3
Beta strandi77 – 81Combined sources5
Beta strandi88 – 96Combined sources9
Turni97 – 99Combined sources3
Beta strandi101 – 108Combined sources8
Beta strandi114 – 116Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BMWNMR-A27-122[»]
1WHOX-ray1.90A27-122[»]
1WHPX-ray3.00A27-122[»]
2VXQX-ray1.90A27-122[»]
ProteinModelPortaliP43214.
SMRiP43214.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP43214.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 120Expansin-like CBDPROSITE-ProRule annotationAdd BLAST80

Sequence similaritiesi

Belongs to the expansin family. Expansin B subfamily.Curated
Contains 1 expansin-like CBD domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.40.760. 1 hit.
InterProiIPR005453. Allergen_Lolp2.
IPR007117. Expansin_CBD.
[Graphical view]
PfamiPF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01637. LOLP2ALLERGN.
SUPFAMiSSF49590. SSF49590. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43214-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMASSSSSS LLAMAVLAAL FAGAWCVPKV TFTVEKGSNE KHLAVLVKYE
60 70 80 90 100
GDTMAEVELR EHGSDEWVAM TKGEGGVWTF DSEEPLQGPF NFRFLTEKGM
110 120
KNVFDDVVPE KYTIGATYAP EE
Length:122
Mass (Da):13,362
Last modified:November 1, 1995 - v1
Checksum:i708B911B25EE26F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X75925 mRNA. Translation: CAA53529.1.
PIRiS39457.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X75925 mRNA. Translation: CAA53529.1.
PIRiS39457.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BMWNMR-A27-122[»]
1WHOX-ray1.90A27-122[»]
1WHPX-ray3.00A27-122[»]
2VXQX-ray1.90A27-122[»]
ProteinModelPortaliP43214.
SMRiP43214.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3419. Phl p 2.0101.
555. Phl p 2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP43214.

Family and domain databases

Gene3Di2.60.40.760. 1 hit.
InterProiIPR005453. Allergen_Lolp2.
IPR007117. Expansin_CBD.
[Graphical view]
PfamiPF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01637. LOLP2ALLERGN.
SUPFAMiSSF49590. SSF49590. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMPAP2_PHLPR
AccessioniPrimary (citable) accession number: P43214
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.