Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Pollen allergen Phl p 1

Gene

PHLPI

Organism
Phleum pratense (Common timothy)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Pollen allergen Phl p 1
Alternative name(s):
Allergen Phl p I
Allergen: Phl p 1
Gene namesi
Name:PHLPI
OrganismiPhleum pratense (Common timothy)
Taxonomic identifieri15957 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaePoodaePoeaePoeae Chloroplast Group 2 (Poeae type)PoinaePhleum

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Causes grass pollen allergy. Binds to IgE.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei549. Phl p 1.
551. Phl p 1.0102.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 263240Pollen allergen Phl p 1PRO_0000008722Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi32 – 321N-linked (GlcNAc...)1 Publication
Disulfide bondi64 ↔ 92
Disulfide bondi95 ↔ 162
Disulfide bondi100 ↔ 106

Keywords - PTMi

Disulfide bond, Glycoprotein

Interactioni

Subunit structurei

Homodimer.1 Publication

Structurei

Secondary structure

1
263
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi42 – 498Combined sources
Turni72 – 765Combined sources
Beta strandi78 – 814Combined sources
Helixi83 – 864Combined sources
Helixi87 – 893Combined sources
Beta strandi95 – 1006Combined sources
Beta strandi111 – 1188Combined sources
Beta strandi123 – 1319Combined sources
Helixi132 – 1365Combined sources
Helixi144 – 1485Combined sources
Beta strandi152 – 1598Combined sources
Beta strandi171 – 1744Combined sources
Beta strandi182 – 1887Combined sources
Beta strandi196 – 2038Combined sources
Turni216 – 2183Combined sources
Beta strandi220 – 2234Combined sources
Beta strandi232 – 24110Combined sources
Beta strandi243 – 2508Combined sources
Beta strandi256 – 2616Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1N10X-ray2.90A/B23-263[»]
ProteinModelPortaliP43213.
SMRiP43213. Positions 25-262.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP43213.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini61 – 167107Expansin-like EG45PROSITE-ProRule annotationAdd
BLAST
Domaini181 – 26282Expansin-like CBDPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the expansin family. Expansin B subfamily.Curated
Contains 1 expansin-like CBD domain.PROSITE-ProRule annotation
Contains 1 expansin-like EG45 domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR005795. LolPI.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01225. EXPANSNFAMLY.
PR00829. LOLP1ALLERGN.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43213-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSSSVLLV VVLFAVFLGS AYGIPKVPPG PNITATYGDK WLDAKSTWYG
60 70 80 90 100
KPTGAGPKDN GGACGYKDVD KPPFSGMTGC GNTPIFKSGR GCGSCFEIKC
110 120 130 140 150
TKPEACSGEP VVVHITDDNE EPIAPYHFDL SGHAFGAMAK KGDEQKLRSA
160 170 180 190 200
GELELQFRRV KCKYPEGTKV TFHVEKGSNP NYLALLVKYV NGDGDVVAVD
210 220 230 240 250
IKEKGKDKWI ELKESWGAIW RIDTPDKLTG PFTVRYTTEG GTKTEAEDVI
260
PEGWKADTSY ESK
Length:263
Mass (Da):28,457
Last modified:November 1, 1995 - v1
Checksum:i046BA249C17BC048
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78813 mRNA. Translation: CAA55390.1.
PIRiS44182.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78813 mRNA. Translation: CAA55390.1.
PIRiS44182.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1N10X-ray2.90A/B23-263[»]
ProteinModelPortaliP43213.
SMRiP43213. Positions 25-262.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei549. Phl p 1.
551. Phl p 1.0102.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP43213.

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR005795. LolPI.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01225. EXPANSNFAMLY.
PR00829. LOLP1ALLERGN.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMPAP1_PHLPR
AccessioniPrimary (citable) accession number: P43213
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 17, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.