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P43187 (ALLB3_BETPN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Calcium-binding allergen Bet v 3
Alternative name(s):
Allergen Bet v III
Allergen=Bet v 3
Gene names
Name:BETVIII
OrganismBetula pendula (European white birch) (Betula verrucosa)
Taxonomic identifier3505 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFagalesBetulaceaeBetula

Protein attributes

Sequence length205 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Could be involved in calcium metabolism in pollen. Binds 3 calcium ions.

Allergenic properties

Causes an allergic reaction in human.

Sequence similarities

Contains 4 EF-hand domains.

Ontologies

Keywords
   DiseaseAllergen
   DomainRepeat
   LigandCalcium
Metal-binding
Gene Ontology (GO)
   Molecular_functioncalcium ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 205205Calcium-binding allergen Bet v 3
PRO_0000073662

Regions

Domain36 – 7136EF-hand 1
Domain72 – 10736EF-hand 2
Domain130 – 16536EF-hand 3
Domain168 – 20336EF-hand 4
Calcium binding49 – 60121 Potential
Calcium binding143 – 154122 Potential
Calcium binding181 – 192123 Potential

Sequences

Sequence LengthMass (Da)Tools
P43187 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 390BE386C0FEF05C

FASTA20523,142
        10         20         30         40         50         60 
MPCSTEAMEK AGHGHASTPR KRSLSNSSFR LRSESLNTLR LRRIFDLFDK NSDGIITVDE 

        70         80         90        100        110        120 
LSRALNLLGL ETDLSELEST VKSFTREGNI GLQFEDFISL HQSLNDSYFA YGGEDEDDNE 

       130        140        150        160        170        180 
EDMRKSILSQ EEADSFGGFK VFDEDGDGYI SARELQMVLG KLGFSEGSEI DRVEKMIVSV 

       190        200 
DSNRDGRVDF FEFKDMMRSV LVRSS 

« Hide

References

[1]"Characterization of a birch pollen allergen, Bet v III, representing a novel class of Ca2+ binding proteins: specific expression in mature pollen and dependence of patients' IgE binding on protein-bound Ca2+."
Seiberler S., Scheiner O., Kraft D., Lonsdale D., Valenta R.
EMBO J. 13:3481-3486(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], SYNTHESIS OF CALCIUM-BINDING SITES.
Tissue: Pollen.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X79267 mRNA. Translation: CAA55854.1.
PIRS46233.

3D structure databases

ProteinModelPortalP43187.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome128. Bet v 3.
3137. Bet v 3.0101.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.238.10. 2 hits.
InterProIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamPF00036. EF-hand_1. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTSM00054. EFh. 3 hits.
[Graphical view]
PROSITEPS00018. EF_HAND_1. 3 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALLB3_BETPN
AccessionPrimary (citable) accession number: P43187
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 19, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries