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P43186

- BEV1M_BETPN

UniProt

P43186 - BEV1M_BETPN

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Protein

Major pollen allergen Bet v 1-M/N

Gene

BETV1M

more
Organism
Betula pendula (European white birch) (Betula verrucosa)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

May be a general steroid carrier protein.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei95 – 951SubstrateBy similarity
Binding sitei121 – 1211SubstrateBy similarity
Binding sitei127 – 1271SubstrateBy similarity

GO - Biological processi

  1. defense response Source: UniProtKB-KW
  2. response to biotic stimulus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Pathogenesis-related protein

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Major pollen allergen Bet v 1-M/N
Alternative name(s):
Allergen Bet v I-M/N
Allergen: Bet v 1-M/N
Gene namesi
Name:BETV1M
AND
Name:BETV1N
OrganismiBetula pendula (European white birch) (Betula verrucosa)
Taxonomic identifieri3505 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFagalesBetulaceaeBetula

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Is a cause of type I allergic reactions in Europe, North America and USSR.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei107. Bet v 1.0204.
89. Bet v 1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed
Chaini2 – 160159Major pollen allergen Bet v 1-M/NPRO_0000154184Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP43186.
SMRiP43186. Positions 2-160.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BetVI family.Curated

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR024949. Bet_v_I_allergen.
IPR000916. Bet_v_I_dom.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF00407. Bet_v_1. 1 hit.
[Graphical view]
PRINTSiPR00634. BETALLERGEN.
PROSITEiPS00451. PATHOGENESIS_BETVI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43186-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGVFNYESET TSVIPAARLF KAFILDGDNL IPKVAPQAIS SVENIEGNGG
60 70 80 90 100
PGTIKKITFP EGSPFKYVKE RVDEVDHANF KYSYSMIEGG ALGDTLEKIC
110 120 130 140 150
NEIKIVATPD GGSILKISNK YHTKGDHEMK AEHMKAIKEK GEALLRAVES
160
YLLAHSDAYN
Length:160
Mass (Da):17,522
Last modified:January 23, 2007 - v2
Checksum:i54F5D4F174F91CC2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X81972 mRNA. Translation: CAA57497.1.
X82028 mRNA. Translation: CAA57550.1.
PIRiA57427.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X81972 mRNA. Translation: CAA57497.1 .
X82028 mRNA. Translation: CAA57550.1 .
PIRi A57427.

3D structure databases

ProteinModelPortali P43186.
SMRi P43186. Positions 2-160.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 107. Bet v 1.0204.
89. Bet v 1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.30.530.20. 1 hit.
InterProi IPR024949. Bet_v_I_allergen.
IPR000916. Bet_v_I_dom.
IPR023393. START-like_dom.
[Graphical view ]
Pfami PF00407. Bet_v_1. 1 hit.
[Graphical view ]
PRINTSi PR00634. BETALLERGEN.
PROSITEi PS00451. PATHOGENESIS_BETVI. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Isoforms of Bet v 1, the major birch pollen allergen, analyzed by liquid chromatography, mass spectrometry, and cDNA cloning."
    Swoboda I., Jilek A., Ferreira F., Engel E., Hoffman-Sommergruber K., Scheiner O., Kraft D., Breiteneder H., Pittenauer E., Schmid E., Vicente O., Heberle-Bors E., Ahorn H., Breitenbach M.
    J. Biol. Chem. 270:2607-2613(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
    Tissue: Pollen.

Entry informationi

Entry nameiBEV1M_BETPN
AccessioniPrimary (citable) accession number: P43186
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3