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P43186 (BEV1M_BETPN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Major pollen allergen Bet v 1-M/N
Alternative name(s):
Allergen Bet v I-M/N
Allergen=Bet v 1-M/N
Gene names
Name:BETV1M
AND
Name:BETV1N
OrganismBetula pendula (European white birch) (Betula verrucosa)
Taxonomic identifier3505 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFagalesBetulaceaeBetula

Protein attributes

Sequence length160 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May be a general steroid carrier protein By similarity.

Subcellular location

Cytoplasm.

Allergenic properties

Causes an allergic reaction in human. Is a cause of type I allergic reactions in Europe, North America and USSR.

Sequence similarities

Belongs to the BetVI family.

Ontologies

Keywords
   Biological processPlant defense
   Cellular componentCytoplasm
   DiseaseAllergen
   Molecular functionPathogenesis-related protein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processdefense response

Inferred from electronic annotation. Source: UniProtKB-KW

response to biotic stimulus

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed
Chain2 – 160159Major pollen allergen Bet v 1-M/N
PRO_0000154184

Sites

Binding site951Substrate By similarity
Binding site1211Substrate By similarity
Binding site1271Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
P43186 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: 54F5D4F174F91CC2

FASTA16017,522
        10         20         30         40         50         60 
MGVFNYESET TSVIPAARLF KAFILDGDNL IPKVAPQAIS SVENIEGNGG PGTIKKITFP 

        70         80         90        100        110        120 
EGSPFKYVKE RVDEVDHANF KYSYSMIEGG ALGDTLEKIC NEIKIVATPD GGSILKISNK 

       130        140        150        160 
YHTKGDHEMK AEHMKAIKEK GEALLRAVES YLLAHSDAYN 

« Hide

References

[1]"Isoforms of Bet v 1, the major birch pollen allergen, analyzed by liquid chromatography, mass spectrometry, and cDNA cloning."
Swoboda I., Jilek A., Ferreira F., Engel E., Hoffman-Sommergruber K., Scheiner O., Kraft D., Breiteneder H., Pittenauer E., Schmid E., Vicente O., Heberle-Bors E., Ahorn H., Breitenbach M.
J. Biol. Chem. 270:2607-2613(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
Tissue: Pollen.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X81972 mRNA. Translation: CAA57497.1.
X82028 mRNA. Translation: CAA57550.1.
PIRA57427.

3D structure databases

ProteinModelPortalP43186.
SMRP43186. Positions 2-160.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome107. Bet v 1.0204.
89. Bet v 1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.30.530.20. 1 hit.
InterProIPR024949. Bet_v_I_allergen.
IPR000916. Bet_v_I_dom.
IPR023393. START-like_dom.
[Graphical view]
PfamPF00407. Bet_v_1. 1 hit.
[Graphical view]
PRINTSPR00634. BETALLERGEN.
PROSITEPS00451. PATHOGENESIS_BETVI. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBEV1M_BETPN
AccessionPrimary (citable) accession number: P43186
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 65 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries