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Protein

Major pollen allergen Bet v 1-J

Gene

BETV1J

Organism
Betula pendula (European white birch) (Betula verrucosa)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May be a general steroid carrier protein.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei70BrassinosteroidBy similarity1
Binding sitei95BrassinosteroidBy similarity1
Binding sitei121BrassinosteroidBy similarity1
Binding sitei127BrassinosteroidBy similarity1

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Pathogenesis-related protein

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Major pollen allergen Bet v 1-J
Alternative name(s):
Allergen Bet v I-J
Allergen: Bet v 1-J
Gene namesi
Name:BETV1J
OrganismiBetula pendula (European white birch) (Betula verrucosa)
Taxonomic identifieri3505 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFagalesBetulaceaeBetula

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Is a cause of type I allergic reactions in Europe, North America and USSR.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei101. Bet v 1.0106.
89. Bet v 1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved
ChainiPRO_00001541812 – 160Major pollen allergen Bet v 1-JAdd BLAST159

Structurei

Secondary structure

1160
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 14Combined sources12
Helixi16 – 23Combined sources8
Turni24 – 26Combined sources3
Helixi27 – 34Combined sources8
Turni36 – 38Combined sources3
Beta strandi41 – 46Combined sources6
Beta strandi48 – 50Combined sources3
Beta strandi54 – 58Combined sources5
Beta strandi66 – 76Combined sources11
Turni77 – 80Combined sources4
Beta strandi81 – 89Combined sources9
Beta strandi96 – 107Combined sources12
Beta strandi113 – 126Combined sources14
Helixi132 – 154Combined sources23
Turni156 – 159Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4A8UX-ray1.16A2-160[»]
4A8VX-ray1.23A2-160[»]
ProteinModelPortaliP43183.
SMRiP43183.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BetVI family.Curated

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR000916. Bet_v_I/MLP.
IPR024949. Bet_v_I_allergen.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF00407. Bet_v_1. 1 hit.
[Graphical view]
PRINTSiPR00634. BETALLERGEN.
SMARTiSM01037. Bet_v_1. 1 hit.
[Graphical view]
PROSITEiPS00451. PATHOGENESIS_BETVI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43183-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVFNYETEA TSVIPAARLF KAFILDGDNL FPKVAPQAIS SVENIEGNGG
60 70 80 90 100
PGTIKKISFP EGFPFKYVKD RVDEVDHTNF KYSYSVIEGG PVGDTLEKIS
110 120 130 140 150
NEIKIVATPN GGSILKINNK YHTKGDHEVK AEQIKASKEM GETLLRAVES
160
YLLAHSDAYN
Length:160
Mass (Da):17,540
Last modified:January 23, 2007 - v2
Checksum:i2DF9E6E0171193AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77271 mRNA. Translation: CAA54487.1.
PIRiG55699.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77271 mRNA. Translation: CAA54487.1.
PIRiG55699.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4A8UX-ray1.16A2-160[»]
4A8VX-ray1.23A2-160[»]
ProteinModelPortaliP43183.
SMRiP43183.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei101. Bet v 1.0106.
89. Bet v 1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR000916. Bet_v_I/MLP.
IPR024949. Bet_v_I_allergen.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF00407. Bet_v_1. 1 hit.
[Graphical view]
PRINTSiPR00634. BETALLERGEN.
SMARTiSM01037. Bet_v_1. 1 hit.
[Graphical view]
PROSITEiPS00451. PATHOGENESIS_BETVI. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBEV1J_BETPN
AccessioniPrimary (citable) accession number: P43183
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.