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Protein

Small neutral protease regulatory protein

Gene

mprR

Organism
Streptomyces coelicolor
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Transcriptional trans-activator of the gene (mprA) for the small neutral protease.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi16 – 35H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Small neutral protease regulatory protein
Gene namesi
Name:mprR
OrganismiStreptomyces coelicolor
Taxonomic identifieri1902 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001056831 – 316Small neutral protease regulatory proteinAdd BLAST316

Structurei

3D structure databases

ProteinModelPortaliP43160.
SMRiP43160.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 56HTH lysR-typePROSITE-ProRule annotationAdd BLAST56

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PfamiView protein in Pfam
PF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS50931. HTH_LYSR. 1 hit.

Sequencei

Sequence statusi: Complete.

P43160-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRHLRALCAI ADTGSVRRAA RELGVSQPAL TTQLRRIEQS LGAELFHRGR
60 70 80 90 100
DGCRPTLLGR TVLSRARTVV DSMAVLVEEA RAEAAALGRP GPRLRVGSTA
110 120 130 140 150
SRIVGDWLRR LRGRMPETDI TLQVDVSATV LLRCCAPAAL DLAFVHEVEG
160 170 180 190 200
SPLRVPDGLV QHTLLEREPQ FISLAPDHPA AARPVVDLAD LAQDRWMVDP
210 220 230 240 250
SVDGEWDGVR RVLAAAGIDP PVLHGDYLTT ASLVALGEAV APCQPTSGPR
260 270 280 290 300
DDMVIRPLRD DPLAVRLLLV TPPRCPAAGP AYEELTAAYA AAALRAGPYR
310
EWLEGAPERP GALLGG
Length:316
Mass (Da):33,888
Last modified:November 1, 1995 - v1
Checksum:i9B39A580A2C8CC44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z11929 Genomic DNA. Translation: CAA77986.1.
PIRiS25188.

Similar proteinsi

Entry informationi

Entry nameiMPRR1_STRCH
AccessioniPrimary (citable) accession number: P43160
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 31, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program