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Protein

Ornithine decarboxylase, inducible

Gene

odcI

Organism
Lactobacillus sp. (strain 30a)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

L-ornithine = putrescine + CO2.

Cofactori

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BRENDAi4.1.1.17. 13668.
SABIO-RKP43099.

Names & Taxonomyi

Protein namesi
Recommended name:
Ornithine decarboxylase, inducible (EC:4.1.1.17)
Short name:
ODC
Gene namesi
Name:odcI
OrganismiLactobacillus sp. (strain 30a)
Taxonomic identifieri1593 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved
ChainiPRO_00002011372 – 731Ornithine decarboxylase, inducibleAdd BLAST730

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei356N6-(pyridoxal phosphate)lysine1

Expressioni

Inductioni

By ornithine.

Interactioni

Subunit structurei

Dodecamer.

Structurei

Secondary structure

1731
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi6 – 9Combined sources4
Helixi11 – 16Combined sources6
Beta strandi27 – 29Combined sources3
Beta strandi31 – 40Combined sources10
Helixi44 – 51Combined sources8
Beta strandi59 – 64Combined sources6
Helixi66 – 68Combined sources3
Helixi71 – 74Combined sources4
Beta strandi79 – 82Combined sources4
Helixi92 – 107Combined sources16
Helixi110 – 119Combined sources10
Beta strandi127 – 129Combined sources3
Turni130 – 136Combined sources7
Helixi137 – 139Combined sources3
Helixi141 – 150Combined sources10
Helixi153 – 156Combined sources4
Helixi164 – 166Combined sources3
Turni169 – 172Combined sources4
Helixi175 – 186Combined sources12
Beta strandi190 – 197Combined sources8
Helixi198 – 210Combined sources13
Beta strandi216 – 220Combined sources5
Helixi225 – 231Combined sources7
Turni232 – 235Combined sources4
Beta strandi238 – 242Combined sources5
Beta strandi244 – 246Combined sources3
Beta strandi252 – 255Combined sources4
Helixi257 – 259Combined sources3
Helixi262 – 268Combined sources7
Turni269 – 271Combined sources3
Helixi274 – 277Combined sources4
Beta strandi283 – 291Combined sources9
Beta strandi295 – 298Combined sources4
Helixi300 – 307Combined sources8
Helixi308 – 310Combined sources3
Beta strandi311 – 317Combined sources7
Helixi323 – 325Combined sources3
Helixi328 – 333Combined sources6
Beta strandi347 – 352Combined sources6
Helixi354 – 357Combined sources4
Beta strandi365 – 370Combined sources6
Helixi372 – 374Combined sources3
Beta strandi375 – 379Combined sources5
Helixi383 – 393Combined sources11
Helixi400 – 413Combined sources14
Helixi415 – 438Combined sources24
Beta strandi442 – 447Combined sources6
Beta strandi449 – 451Combined sources3
Helixi456 – 458Combined sources3
Helixi461 – 464Combined sources4
Helixi468 – 471Combined sources4
Turni478 – 480Combined sources3
Beta strandi490 – 492Combined sources3
Beta strandi496 – 500Combined sources5
Beta strandi502 – 505Combined sources4
Turni506 – 509Combined sources4
Helixi518 – 527Combined sources10
Beta strandi533 – 535Combined sources3
Beta strandi537 – 543Combined sources7
Helixi550 – 568Combined sources19
Helixi573 – 576Combined sources4
Helixi578 – 581Combined sources4
Turni585 – 587Combined sources3
Helixi593 – 605Combined sources13
Turni606 – 608Combined sources3
Helixi609 – 615Combined sources7
Helixi619 – 621Combined sources3
Beta strandi624 – 627Combined sources4
Helixi629 – 637Combined sources9
Beta strandi641 – 645Combined sources5
Turni646 – 648Combined sources3
Beta strandi652 – 656Combined sources5
Beta strandi658 – 660Combined sources3
Turni661 – 663Combined sources3
Helixi676 – 691Combined sources16
Beta strandi699 – 707Combined sources9
Beta strandi710 – 718Combined sources9
Helixi720 – 724Combined sources5
Helixi727 – 729Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1C4KX-ray2.70A2-731[»]
1ORDX-ray3.00A/B2-731[»]
ProteinModelPortaliP43099.
SMRiP43099.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP43099.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

CDDicd00615. Orn_deC_like. 1 hit.
Gene3Di3.40.50.220. 1 hit.
3.40.640.10. 1 hit.
3.90.100.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR005308. OKR_de-COase_N.
IPR011193. Orn/lys/arg_de-COase.
IPR000310. Orn/Lys/Arg_deCO2ase_major_dom.
IPR027464. Ornithine_deCO2ase_N.
IPR008286. Prn/Lys/Arg_de-COase_C.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF01276. OKR_DC_1. 1 hit.
PF03711. OKR_DC_1_C. 1 hit.
PF03709. OKR_DC_1_N. 1 hit.
[Graphical view]
PIRSFiPIRSF009393. Orn_decarb. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF53383. SSF53383. 1 hit.
SSF55904. SSF55904. 1 hit.
PROSITEiPS00703. OKR_DC_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43099-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSLKIAST QEARQYFDTD RVVVDAVGSD FTDVGAVIAM DYETDVIDAA
60 70 80 90 100
DATKFGIPVF AVTKDAQAIS ADELKKIFHI IDLENKFDAT VNAREIETAV
110 120 130 140 150
NNYEDSILPP FFKSLKEYVS RGLIQFDCPG HQGGQYYRKH PAGREFYDFF
160 170 180 190 200
GETVFRADLC NADVALGDLL IHEGPAVAAE KHAARVYNAD KTYFVLGGSS
210 220 230 240 250
NANNTVTSAL VSNGDLVLFD RNNHKSVYNS ALAMAGGRPV YLQTNRNPYG
260 270 280 290 300
FIGGIYDSDF DEKKIRELAA KVDPERAKWK RPFRLAVIQL GTYDGTIYNA
310 320 330 340 350
HEVVKRIGHL CDYIEFDSAW VGYEQFIPMM RNSSPLLIDD LGPEDPGIIV
360 370 380 390 400
VQSVHKQQAG FSQTSQIHKK DSHIKGQLRY CDHKHFNNSF NLFMSTSPFY
410 420 430 440 450
PMYAALDVNA AMQEGEAGRK LWHDLLITTI EARKKLIKAG SMFRPFVPPV
460 470 480 490 500
VNGKKWEDGD TEDMANNIDY WRFEKGAKWH AYEGYGDNQY YVDPNKFMLT
510 520 530 540 550
TPGINPETGD YEDFGVPATI VANYLRDHGI IPEKSDLNSI LFLMTPAETP
560 570 580 590 600
AKMNNLITQL LQLQRLIEED APLKQVLPSI YAANEERYNG YTIRELCQEL
610 620 630 640 650
HDFYKNNNTF TYQKRLFLRE FFPEQGMLPY EARQEFIRNH NKLVPLNKIE
660 670 680 690 700
GEIALEGALP YPPGVFCVAP GEKWSETAVK YFTILQDGIN NFPGFAPEIQ
710 720 730
GVYFKQEGDK VVAYGEVYDA EVAKNDDRYN N
Length:731
Mass (Da):82,688
Last modified:January 23, 2007 - v2
Checksum:i3652214455C956AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11816 Genomic DNA. Translation: AAA64830.1.
PIRiA55229.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11816 Genomic DNA. Translation: AAA64830.1.
PIRiA55229.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1C4KX-ray2.70A2-731[»]
1ORDX-ray3.00A/B2-731[»]
ProteinModelPortaliP43099.
SMRiP43099.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BRENDAi4.1.1.17. 13668.
SABIO-RKP43099.

Miscellaneous databases

EvolutionaryTraceiP43099.

Family and domain databases

CDDicd00615. Orn_deC_like. 1 hit.
Gene3Di3.40.50.220. 1 hit.
3.40.640.10. 1 hit.
3.90.100.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR005308. OKR_de-COase_N.
IPR011193. Orn/lys/arg_de-COase.
IPR000310. Orn/Lys/Arg_deCO2ase_major_dom.
IPR027464. Ornithine_deCO2ase_N.
IPR008286. Prn/Lys/Arg_de-COase_C.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF01276. OKR_DC_1. 1 hit.
PF03711. OKR_DC_1_C. 1 hit.
PF03709. OKR_DC_1_N. 1 hit.
[Graphical view]
PIRSFiPIRSF009393. Orn_decarb. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF53383. SSF53383. 1 hit.
SSF55904. SSF55904. 1 hit.
PROSITEiPS00703. OKR_DC_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDCOR_LACS3
AccessioniPrimary (citable) accession number: P43099
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.