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Protein

Probable tyrosine-protein phosphatase

Gene

CPP1

Organism
Candida albicans (strain WO-1) (Yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei516Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tyrosine-protein phosphatase (EC:3.1.3.48)
Gene namesi
Name:CPP1
ORF Names:CAWG_00432
OrganismiCandida albicans (strain WO-1) (Yeast)
Taxonomic identifieri294748 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000001429 Componenti: Chromosome 1, Supercontig 1.1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000949181 – 597Probable tyrosine-protein phosphataseAdd BLAST597

Structurei

3D structure databases

ProteinModelPortaliP43078
SMRiP43078
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi56 – 59Poly-Ser4
Compositional biasi68 – 74Poly-Thr7
Compositional biasi375 – 385Poly-AsnAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000093420
OMAiSINAYPN
OrthoDBiEOG092C1CH8

Family and domain databases

CDDicd00127 DSPc, 1 hit
Gene3Di3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR000340 Dual-sp_phosphatase_cat-dom
IPR024950 DUSP
IPR029021 Prot-tyrosine_phosphatase-like
IPR016130 Tyr_Pase_AS
IPR000387 TYR_PHOSPHATASE_dom
IPR020422 TYR_PHOSPHATASE_DUAL_dom
PANTHERiPTHR10159 PTHR10159, 1 hit
PfamiView protein in Pfam
PF00782 DSPc, 1 hit
SMARTiView protein in SMART
SM00195 DSPc, 1 hit
PROSITEiView protein in PROSITE
PS00383 TYR_PHOSPHATASE_1, 1 hit
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50054 TYR_PHOSPHATASE_DUAL, 1 hit

Sequencei

Sequence statusi: Complete.

P43078-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTPLSSYST TVTNHHPTFS FESLNSISSN NSTRNNQSNS VNSLLYFNSS
60 70 80 90 100
GSSMVSSSSD AAPTSISTTT TSTTSMTDAS ANADNQQVYT ITEEDSINDI
110 120 130 140 150
NRKEQNSFSI QPNQTPTMLP TSSYTLQRPP GLHEYTSSIS SISSTSSNST
160 170 180 190 200
SAPVSPALIN YSPKHSRKPN SLNLNRNMKN LSLNLHDSTN GYTSPLPKST
210 220 230 240 250
NSNQPRGNFI MDSPSKKSTP VNRIGNNNGN DYINATLLQT PSITQTPTMP
260 270 280 290 300
PPLSLAQGPP SSVGSESVYK FPLISNACLN YSAGDSDSEV ESISMKQAAK
310 320 330 340 350
NTIIPPMAPP FALQSKSSPL STPPRLHSPL GVDRGLPISM SPIQSSLNQK
360 370 380 390 400
FNNITLQTPL NSSFSINNDE ATNFNNKNNK NNNNNSTATT TITNTILSTP
410 420 430 440 450
QNVRYNSKKF HPPEELQEST SINAYPNGPK NVLNNLIYLY SDPAQGKIDI
460 470 480 490 500
NKFDLVINVA KECDNMSLQY MNQVPNQREY VYIPWSHNSN ISKDLFQITN
510 520 530 540 550
KIDQFFTNGR KILIHCQCGV SRSACVVVAF YMKKFQLGVN EAYELLKNGD
560 570 580 590
QKYIDACDRI CPNMNLIFEL MEFGDKLNNN EISTQQLLMN SPPTINL
Length:597
Mass (Da):65,586
Last modified:October 19, 2011 - v2
Checksum:iB0F1DE22ACC9C78C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti504Q → K in AAC05307 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L01038 Genomic DNA Translation: AAC05307.1
CH672346 Genomic DNA Translation: EEQ42230.1
PIRiS43743

Genome annotation databases

EnsemblFungiiEEQ42230; EEQ42230; CAWG_00432

Similar proteinsi

Entry informationi

Entry nameiPTPX_CANAW
AccessioniPrimary (citable) accession number: P43078
Secondary accession number(s): C4YD44
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 19, 2011
Last modified: March 28, 2018
This is version 73 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health