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P43078 (PTPX_CANAW) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable tyrosine-protein phosphatase

EC=3.1.3.48
Gene names
Name:CPP1
ORF Names:CAWG_00432
OrganismCandida albicans (strain WO-1) (Yeast) [Complete proteome]
Taxonomic identifier294748 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length597 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 597597Probable tyrosine-protein phosphatase
PRO_0000094918

Regions

Compositional bias56 – 594Poly-Ser
Compositional bias68 – 747Poly-Thr
Compositional bias375 – 38511Poly-Asn

Sites

Active site5161Phosphocysteine intermediate By similarity

Experimental info

Sequence conflict5041Q → K in AAC05307. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P43078 [UniParc].

Last modified October 19, 2011. Version 2.
Checksum: B0F1DE22ACC9C78C

FASTA59765,586
        10         20         30         40         50         60 
MTTPLSSYST TVTNHHPTFS FESLNSISSN NSTRNNQSNS VNSLLYFNSS GSSMVSSSSD 

        70         80         90        100        110        120 
AAPTSISTTT TSTTSMTDAS ANADNQQVYT ITEEDSINDI NRKEQNSFSI QPNQTPTMLP 

       130        140        150        160        170        180 
TSSYTLQRPP GLHEYTSSIS SISSTSSNST SAPVSPALIN YSPKHSRKPN SLNLNRNMKN 

       190        200        210        220        230        240 
LSLNLHDSTN GYTSPLPKST NSNQPRGNFI MDSPSKKSTP VNRIGNNNGN DYINATLLQT 

       250        260        270        280        290        300 
PSITQTPTMP PPLSLAQGPP SSVGSESVYK FPLISNACLN YSAGDSDSEV ESISMKQAAK 

       310        320        330        340        350        360 
NTIIPPMAPP FALQSKSSPL STPPRLHSPL GVDRGLPISM SPIQSSLNQK FNNITLQTPL 

       370        380        390        400        410        420 
NSSFSINNDE ATNFNNKNNK NNNNNSTATT TITNTILSTP QNVRYNSKKF HPPEELQEST 

       430        440        450        460        470        480 
SINAYPNGPK NVLNNLIYLY SDPAQGKIDI NKFDLVINVA KECDNMSLQY MNQVPNQREY 

       490        500        510        520        530        540 
VYIPWSHNSN ISKDLFQITN KIDQFFTNGR KILIHCQCGV SRSACVVVAF YMKKFQLGVN 

       550        560        570        580        590 
EAYELLKNGD QKYIDACDRI CPNMNLIFEL MEFGDKLNNN EISTQQLLMN SPPTINL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L01038 Genomic DNA. Translation: AAC05307.1.
CH672346 Genomic DNA. Translation: EEQ42230.1.
PIRS43743.

3D structure databases

ProteinModelPortalP43078.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG2453.
HOGENOMHOG000093420.
OMATENENDQ.
OrthoDBEOG7HF1WG.

Family and domain databases

InterProIPR000340. Dual-sp_phosphatase_cat-dom.
IPR020422. Dual-sp_phosphatase_subgr_cat.
IPR024950. DUSP.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
[Graphical view]
PANTHERPTHR10159. PTHR10159. 1 hit.
PfamPF00782. DSPc. 1 hit.
[Graphical view]
SMARTSM00195. DSPc. 1 hit.
[Graphical view]
PROSITEPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePTPX_CANAW
AccessionPrimary (citable) accession number: P43078
Secondary accession number(s): C4YD44
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 19, 2011
Last modified: April 16, 2014
This is version 58 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families