Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable tyrosine-protein phosphatase

Gene

CPP1

Organism
Candida albicans (strain WO-1) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei516Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tyrosine-protein phosphatase (EC:3.1.3.48)
Gene namesi
Name:CPP1
ORF Names:CAWG_00432
OrganismiCandida albicans (strain WO-1) (Yeast)
Taxonomic identifieri294748 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000001429 Componenti: Chromosome 1, Supercontig 1.1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000949181 – 597Probable tyrosine-protein phosphataseAdd BLAST597

Structurei

3D structure databases

ProteinModelPortaliP43078.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi56 – 59Poly-Ser4
Compositional biasi68 – 74Poly-Thr7
Compositional biasi375 – 385Poly-AsnAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000093420.
OMAiSTSINAY.
OrthoDBiEOG092C1CH8.

Family and domain databases

CDDicd00127. DSPc. 1 hit.
Gene3Di3.90.190.10. 1 hit.
InterProiIPR000340. Dual-sp_phosphatase_cat-dom.
IPR024950. DUSP.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR000387. TYR_PHOSPHATASE_dom.
IPR020422. TYR_PHOSPHATASE_DUAL_dom.
[Graphical view]
PANTHERiPTHR10159. PTHR10159. 2 hits.
PfamiPF00782. DSPc. 1 hit.
[Graphical view]
SMARTiSM00195. DSPc. 1 hit.
[Graphical view]
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P43078-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTPLSSYST TVTNHHPTFS FESLNSISSN NSTRNNQSNS VNSLLYFNSS
60 70 80 90 100
GSSMVSSSSD AAPTSISTTT TSTTSMTDAS ANADNQQVYT ITEEDSINDI
110 120 130 140 150
NRKEQNSFSI QPNQTPTMLP TSSYTLQRPP GLHEYTSSIS SISSTSSNST
160 170 180 190 200
SAPVSPALIN YSPKHSRKPN SLNLNRNMKN LSLNLHDSTN GYTSPLPKST
210 220 230 240 250
NSNQPRGNFI MDSPSKKSTP VNRIGNNNGN DYINATLLQT PSITQTPTMP
260 270 280 290 300
PPLSLAQGPP SSVGSESVYK FPLISNACLN YSAGDSDSEV ESISMKQAAK
310 320 330 340 350
NTIIPPMAPP FALQSKSSPL STPPRLHSPL GVDRGLPISM SPIQSSLNQK
360 370 380 390 400
FNNITLQTPL NSSFSINNDE ATNFNNKNNK NNNNNSTATT TITNTILSTP
410 420 430 440 450
QNVRYNSKKF HPPEELQEST SINAYPNGPK NVLNNLIYLY SDPAQGKIDI
460 470 480 490 500
NKFDLVINVA KECDNMSLQY MNQVPNQREY VYIPWSHNSN ISKDLFQITN
510 520 530 540 550
KIDQFFTNGR KILIHCQCGV SRSACVVVAF YMKKFQLGVN EAYELLKNGD
560 570 580 590
QKYIDACDRI CPNMNLIFEL MEFGDKLNNN EISTQQLLMN SPPTINL
Length:597
Mass (Da):65,586
Last modified:October 19, 2011 - v2
Checksum:iB0F1DE22ACC9C78C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti504Q → K in AAC05307 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L01038 Genomic DNA. Translation: AAC05307.1.
CH672346 Genomic DNA. Translation: EEQ42230.1.
PIRiS43743.

Genome annotation databases

EnsemblFungiiEEQ42230; EEQ42230; CAWG_00432.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L01038 Genomic DNA. Translation: AAC05307.1.
CH672346 Genomic DNA. Translation: EEQ42230.1.
PIRiS43743.

3D structure databases

ProteinModelPortaliP43078.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEEQ42230; EEQ42230; CAWG_00432.

Phylogenomic databases

HOGENOMiHOG000093420.
OMAiSTSINAY.
OrthoDBiEOG092C1CH8.

Family and domain databases

CDDicd00127. DSPc. 1 hit.
Gene3Di3.90.190.10. 1 hit.
InterProiIPR000340. Dual-sp_phosphatase_cat-dom.
IPR024950. DUSP.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR000387. TYR_PHOSPHATASE_dom.
IPR020422. TYR_PHOSPHATASE_DUAL_dom.
[Graphical view]
PANTHERiPTHR10159. PTHR10159. 2 hits.
PfamiPF00782. DSPc. 1 hit.
[Graphical view]
SMARTiSM00195. DSPc. 1 hit.
[Graphical view]
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPTPX_CANAW
AccessioniPrimary (citable) accession number: P43078
Secondary accession number(s): C4YD44
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 19, 2011
Last modified: November 30, 2016
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.