SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P43078

- PTPX_CANAW

UniProt

P43078 - PTPX_CANAW

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable tyrosine-protein phosphatase

Gene
CPP1, CAWG_00432
Organism
Candida albicans (strain WO-1) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei516 – 5161Phosphocysteine intermediate By similarity

GO - Molecular functioni

  1. protein tyrosine/serine/threonine phosphatase activity Source: InterPro
  2. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tyrosine-protein phosphatase (EC:3.1.3.48)
Gene namesi
Name:CPP1
ORF Names:CAWG_00432
OrganismiCandida albicans (strain WO-1) (Yeast)
Taxonomic identifieri294748 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
ProteomesiUP000001429: Chromosome 1, Supercontig 1.1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 597597Probable tyrosine-protein phosphatasePRO_0000094918Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP43078.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi56 – 594Poly-Ser
Compositional biasi68 – 747Poly-Thr
Compositional biasi375 – 38511Poly-AsnAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2453.
HOGENOMiHOG000093420.
OMAiREYIARI.
OrthoDBiEOG7HF1WG.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR000340. Dual-sp_phosphatase_cat-dom.
IPR020422. Dual-sp_phosphatase_subgr_cat.
IPR024950. DUSP.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
[Graphical view]
PANTHERiPTHR10159. PTHR10159. 1 hit.
PfamiPF00782. DSPc. 1 hit.
[Graphical view]
SMARTiSM00195. DSPc. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P43078-1 [UniParc]FASTAAdd to Basket

« Hide

MTTPLSSYST TVTNHHPTFS FESLNSISSN NSTRNNQSNS VNSLLYFNSS    50
GSSMVSSSSD AAPTSISTTT TSTTSMTDAS ANADNQQVYT ITEEDSINDI 100
NRKEQNSFSI QPNQTPTMLP TSSYTLQRPP GLHEYTSSIS SISSTSSNST 150
SAPVSPALIN YSPKHSRKPN SLNLNRNMKN LSLNLHDSTN GYTSPLPKST 200
NSNQPRGNFI MDSPSKKSTP VNRIGNNNGN DYINATLLQT PSITQTPTMP 250
PPLSLAQGPP SSVGSESVYK FPLISNACLN YSAGDSDSEV ESISMKQAAK 300
NTIIPPMAPP FALQSKSSPL STPPRLHSPL GVDRGLPISM SPIQSSLNQK 350
FNNITLQTPL NSSFSINNDE ATNFNNKNNK NNNNNSTATT TITNTILSTP 400
QNVRYNSKKF HPPEELQEST SINAYPNGPK NVLNNLIYLY SDPAQGKIDI 450
NKFDLVINVA KECDNMSLQY MNQVPNQREY VYIPWSHNSN ISKDLFQITN 500
KIDQFFTNGR KILIHCQCGV SRSACVVVAF YMKKFQLGVN EAYELLKNGD 550
QKYIDACDRI CPNMNLIFEL MEFGDKLNNN EISTQQLLMN SPPTINL 597
Length:597
Mass (Da):65,586
Last modified:October 19, 2011 - v2
Checksum:iB0F1DE22ACC9C78C
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti504 – 5041Q → K in AAC05307. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L01038 Genomic DNA. Translation: AAC05307.1.
CH672346 Genomic DNA. Translation: EEQ42230.1.
PIRiS43743.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L01038 Genomic DNA. Translation: AAC05307.1 .
CH672346 Genomic DNA. Translation: EEQ42230.1 .
PIRi S43743.

3D structure databases

ProteinModelPortali P43078.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi COG2453.
HOGENOMi HOG000093420.
OMAi REYIARI.
OrthoDBi EOG7HF1WG.

Family and domain databases

Gene3Di 3.90.190.10. 1 hit.
InterProi IPR000340. Dual-sp_phosphatase_cat-dom.
IPR020422. Dual-sp_phosphatase_subgr_cat.
IPR024950. DUSP.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
[Graphical view ]
PANTHERi PTHR10159. PTHR10159. 1 hit.
Pfami PF00782. DSPc. 1 hit.
[Graphical view ]
SMARTi SM00195. DSPc. 1 hit.
[Graphical view ]
SUPFAMi SSF52799. SSF52799. 1 hit.
PROSITEi PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Csank C., Dignard D., Thomas D.Y., Whiteway M.
    Submitted (AUG-1992) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: WO-1.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WO-1.

Entry informationi

Entry nameiPTPX_CANAW
AccessioniPrimary (citable) accession number: P43078
Secondary accession number(s): C4YD44
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 19, 2011
Last modified: June 11, 2014
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi