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P43064

- EFG1_CANAX

UniProt

P43064 - EFG1_CANAX

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Protein

Enhanced filamentous growth protein

Gene
EFG1, EFG
Organism
Candida albicans (Yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Putative transcription factor that stimulates pseudohyphal morphogenesis.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi238 – 25922H-T-H motif By similarityAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Enhanced filamentous growth protein
Gene namesi
Name:EFG1
Synonyms:EFG
OrganismiCandida albicans (Yeast)
Taxonomic identifieri5476 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Subcellular locationi

Nucleus Reviewed prediction

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 552552Enhanced filamentous growth proteinPRO_0000086939Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP43064.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini204 – 310107HTH APSES-typeAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi34 – 374Poly-Gln
Compositional biasi46 – 505Poly-Gln
Compositional biasi83 – 9311Poly-GlnAdd
BLAST
Compositional biasi315 – 32612Poly-AlaAdd
BLAST
Compositional biasi332 – 3387Poly-Pro
Compositional biasi438 – 4469Poly-Gln
Compositional biasi470 – 4734Poly-Gln
Compositional biasi483 – 49311Poly-GlnAdd
BLAST
Compositional biasi496 – 4994Poly-Gln

Sequence similaritiesi

Belongs to the EFG1/PHD1/stuA family.

Phylogenomic databases

eggNOGiNOG41372.

Family and domain databases

Gene3Di3.10.260.10. 1 hit.
InterProiIPR018004. KilA_N/APSES_HTH.
IPR003163. Tscrpt_reg_HTH_APSES-type.
[Graphical view]
PfamiPF04383. KilA-N. 1 hit.
[Graphical view]
SUPFAMiSSF54616. SSF54616. 1 hit.
PROSITEiPS51299. HTH_APSES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P43064-1 [UniParc]FASTAAdd to Basket

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MSTYSIPYYN QMNGNYNNGM PQQTTAANQQ AFPQQQQPTT TGNASQQQQQ    50
AAATAAAVQQ PYNYMFYQQQ GQPGQQTGQT AGQQQQQQQQ QQQYDYNTYN 100
RYQYPAATSQ GNYYQQTIPN QLSQPQPQHY NGSNRNYTSA PSGAPIPSNS 150
TSGPSQQPPL PGQQAVPIPP HVSTMQQPTP VQDTLNASST STVGQFQPPG 200
IRPRVTTTMW EDEKTLCYQV DANNVSVVRR ADNNMINGTK LLNVAQMTRG 250
RRDGILKSEK VRHVVKIGSM HLKGVWIPFE RALAMAQREQ IVDMLYPLFV 300
RDIKRVIQTG VTPNAAAATA AAAATATSAS APPPPPPPVA AATTTAATAI 350
SKSSSGNGNS ISATSGGSNV SGASGAGSTT SPVNTKAATA AGIPQGNYYQ 400
TYNQQQYPQQ YGQYNAPGKN QNTPASQPGS TTNDQYLQQQ QQQQQQMYGY 450
QSNYYQGGAA NSSYYPNYYQ QQQPNYASSY PYQQQQQKQQ QQQPNQQQQS 500
DQQQTSTPSG GAGTRSVHQS PQVQSLTQGS VHPSPQQHQA NQSASTVAKE 550
EK 552
Length:552
Mass (Da):59,964
Last modified:November 1, 1995 - v1
Checksum:iF94FD94FC2E06EB7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z32687 Genomic DNA. Translation: CAA83640.1.
PIRiS49338.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z32687 Genomic DNA. Translation: CAA83640.1 .
PIRi S49338.

3D structure databases

ProteinModelPortali P43064.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi NOG41372.

Family and domain databases

Gene3Di 3.10.260.10. 1 hit.
InterProi IPR018004. KilA_N/APSES_HTH.
IPR003163. Tscrpt_reg_HTH_APSES-type.
[Graphical view ]
Pfami PF04383. KilA-N. 1 hit.
[Graphical view ]
SUPFAMi SSF54616. SSF54616. 1 hit.
PROSITEi PS51299. HTH_APSES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi."
    Stoldt V.R., Sonneborn A., Leuker C.E., Ernst J.F.
    EMBO J. 16:1982-1991(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 10231 / CBS 6431 / DSM 1386 / NBRC 1594.

Entry informationi

Entry nameiEFG1_CANAX
AccessioniPrimary (citable) accession number: P43064
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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