P43061 (ARLY_CANAX) Reviewed, UniProtKB/Swiss-Prot
Last modified
October 19, 2011.
Version 66.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Argininosuccinate lyase Short name=ASAL EC=4.3.2.1 Alternative name(s): Arginosuccinase | ||
| Gene names |
| ||
| Organism | Candida albicans (Yeast) | ||
| Taxonomic identifier | 5476 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida |
Protein attributes
| Sequence length | 468 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | 2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. |
| Pathway | |
| Subunit structure | Homotetramer By similarity. |
| Sequence similarities | Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Arginine biosynthesis |
| Molecular function | Lyase |
| Gene Ontology (GO) | |
| Biological process | arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro |
| Molecular function | argininosuccinate lyase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 468 | 468 | Argininosuccinate lyase | PRO_0000137724 | |||
Sequences
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References
| [1] | "The ARG4 gene of Candida albicans." Hoyer L.L., Magee B.B., Rikkerink E.H., Scherer S. Gene 142:213-218(1994) [PubMed: 8194754] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | L25051 Genomic DNA. Translation: AAA34323.2. |
3D structure databases | |
| ProteinModelPortal | P43061. |
| SMR | P43061. Positions 26-467. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | P43061. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Family and domain databases | |
| InterPro | IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR000362. Fumarate_lyase. IPR020557. Fumarate_lyase_CS. IPR008948. L-Aspartase-like. IPR022761. Lyase1_N. [Graphical view] |
| PANTHER | PTHR11444:SF3. argH. 1 hit. |
| Pfam | PF00206. Lyase_1. 1 hit. [Graphical view] |
| PRINTS | PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE. |
| SUPFAM | SSF48557. L-Aspartase-like. 1 hit. |
| TIGRFAMs | TIGR00838. ArgH. 1 hit. |
| PROSITE | PS00163. FUMARATE_LYASES. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ARLY_CANAX | ||||||||
| Accession | Primary (citable) accession number: P43061 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with