Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome c oxidase subunit 6A2, mitochondrial

Gene

Cox6a2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 6A2, mitochondrial
Alternative name(s):
Cytochrome c oxidase polypeptide VIa-heart
Short name:
COXVIAH
Gene namesi
Name:Cox6a2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:104649 Cox6a2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 12MitochondrionBy similarityAdd BLAST12
ChainiPRO_000000611713 – 97Cytochrome c oxidase subunit 6A2, mitochondrialAdd BLAST85

Proteomic databases

MaxQBiP43023
PaxDbiP43023
PeptideAtlasiP43023
PRIDEiP43023

PTM databases

iPTMnetiP43023
PhosphoSitePlusiP43023

Expressioni

Gene expression databases

BgeeiENSMUSG00000030785
CleanExiMM_COX6A2
GenevisibleiP43023 MM

Interactioni

Protein-protein interaction databases

IntActiP43023, 1 interactor
STRINGi10090.ENSMUSP00000033049

Structurei

3D structure databases

ProteinModelPortaliP43023
SMRiP43023
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3469 Eukaryota
ENOG411253X LUCA
GeneTreeiENSGT00390000002756
HOGENOMiHOG000193965
HOVERGENiHBG060482
InParanoidiP43023
KOiK02266
OMAiREPFAKY
OrthoDBiEOG091G0C5F
PhylomeDBiP43023
TreeFamiTF105064

Family and domain databases

CDDicd00925 Cyt_c_Oxidase_VIa, 1 hit
Gene3Di4.10.95.10, 1 hit
InterProiView protein in InterPro
IPR001349 Cyt_c_oxidase_su6a
IPR018507 Cyt_c_oxidase_su6a_CS
IPR036418 Cyt_c_oxidase_su6a_sf
PANTHERiPTHR11504 PTHR11504, 1 hit
PfamiView protein in Pfam
PF02046 COX6A, 1 hit
PIRSFiPIRSF000277 COX6A1, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD006036 Cyt_c_oxidase_su6a, 1 hit
SUPFAMiSSF81411 SSF81411, 1 hit
PROSITEiView protein in PROSITE
PS01329 COX6A, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43023-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALPLKVLSR SMASAAKGDH GGAGANTWRL LTFVLALPGV ALCSLNCWMH
60 70 80 90
AGHHERPEFI PYHHLRIRTK PFAWGDGNHT LFHNPHVNPL PTGYEHP
Length:97
Mass (Da):10,749
Last modified:November 1, 1997 - v2
Checksum:iCECCAC26D332A47F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti39G → S in AAA17835 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U08439 mRNA Translation: AAA17835.1
U34801 Genomic DNA Translation: AAC52280.1
U63716 Genomic DNA Translation: AAB41683.1
AK002506 mRNA Translation: BAB22151.1
CCDSiCCDS21891.1
PIRiI49360
RefSeqiNP_034073.2, NM_009943.2
UniGeneiMm.43824

Genome annotation databases

EnsembliENSMUST00000033049; ENSMUSP00000033049; ENSMUSG00000030785
GeneIDi12862
KEGGimmu:12862
UCSCiuc009jyi.1 mouse

Similar proteinsi

Entry informationi

Entry nameiCX6A2_MOUSE
AccessioniPrimary (citable) accession number: P43023
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1997
Last modified: May 23, 2018
This is version 129 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health