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P43007

- SATT_HUMAN

UniProt

P43007 - SATT_HUMAN

Protein

Neutral amino acid transporter A

Gene

SLC1A4

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 136 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence.

    GO - Molecular functioni

    1. chloride channel activity Source: UniProtKB
    2. L-alanine transmembrane transporter activity Source: UniProtKB
    3. L-cystine transmembrane transporter activity Source: UniProtKB
    4. L-glutamine transmembrane transporter activity Source: BHF-UCL
    5. L-hydroxyproline transmembrane transporter activity Source: UniProtKB
    6. L-proline transmembrane transporter activity Source: UniProtKB
    7. L-serine transmembrane transporter activity Source: UniProtKB
    8. L-threonine transmembrane transporter activity Source: UniProtKB
    9. sodium:dicarboxylate symporter activity Source: InterPro

    GO - Biological processi

    1. amino acid transport Source: Reactome
    2. chloride transmembrane transport Source: GOC
    3. chloride transport Source: GOC
    4. cognition Source: UniProtKB
    5. glutamine transport Source: BHF-UCL
    6. hydroxyproline transport Source: UniProtKB
    7. ion transport Source: Reactome
    8. L-alanine transport Source: UniProtKB
    9. L-cystine transport Source: UniProtKB
    10. L-serine transport Source: UniProtKB
    11. proline transmembrane transport Source: GOC
    12. proline transport Source: UniProtKB
    13. synaptic transmission, glutamatergic Source: UniProtKB
    14. threonine transport Source: UniProtKB
    15. transmembrane transport Source: Reactome

    Keywords - Biological processi

    Symport, Transport

    Enzyme and pathway databases

    ReactomeiREACT_13796. Amino acid transport across the plasma membrane.

    Protein family/group databases

    TCDBi2.A.23.3.1. the dicarboxylate/amino acid:cation (na(+) or h(+)) symporter (daacs) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Neutral amino acid transporter A
    Alternative name(s):
    Alanine/serine/cysteine/threonine transporter 1
    Short name:
    ASCT-1
    SATT
    Solute carrier family 1 member 4
    Gene namesi
    Name:SLC1A4
    Synonyms:ASCT1, SATT
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:10942. SLC1A4.

    Subcellular locationi

    Membrane 1 Publication; Multi-pass membrane protein 1 Publication. Melanosome 1 Publication
    Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

    GO - Cellular componenti

    1. centrosome Source: HPA
    2. dendrite Source: Ensembl
    3. extracellular vesicular exosome Source: UniProt
    4. integral component of membrane Source: UniProtKB
    5. integral component of plasma membrane Source: UniProtKB
    6. intermediate filament Source: UniProtKB
    7. melanosome Source: UniProtKB-SubCell
    8. membrane Source: UniProtKB
    9. microtubule organizing center Source: HPA
    10. neuronal cell body Source: Ensembl
    11. plasma membrane Source: Reactome

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA35829.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 532532Neutral amino acid transporter APRO_0000202079Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11N-acetylmethionine1 Publication
    Glycosylationi201 – 2011N-linked (GlcNAc...)1 Publication
    Glycosylationi206 – 2061N-linked (GlcNAc...)1 Publication
    Modified residuei507 – 5071Phosphoserine1 Publication

    Keywords - PTMi

    Acetylation, Glycoprotein, Phosphoprotein

    Proteomic databases

    MaxQBiP43007.
    PaxDbiP43007.
    PeptideAtlasiP43007.
    PRIDEiP43007.

    PTM databases

    PhosphoSiteiP43007.

    Miscellaneous databases

    PMAP-CutDBP43007.

    Expressioni

    Tissue specificityi

    Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined.

    Gene expression databases

    BgeeiP43007.
    CleanExiHS_SLC1A4.
    GenevestigatoriP43007.

    Organism-specific databases

    HPAiCAB002757.
    HPA034963.
    HPA034964.

    Interactioni

    Protein-protein interaction databases

    BioGridi112400. 2 interactions.
    MINTiMINT-4656683.
    STRINGi9606.ENSP00000234256.

    Structurei

    3D structure databases

    ProteinModelPortaliP43007.
    SMRiP43007. Positions 73-474.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 4141CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini140 – 21677ExtracellularSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei42 – 6221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei88 – 10821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei119 – 13921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei217 – 23721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei257 – 27721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei298 – 31821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei328 – 34821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei373 – 39321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei418 – 43821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1301.
    HOGENOMiHOG000208776.
    HOVERGENiHBG000080.
    InParanoidiP43007.
    KOiK05615.
    OMAiFRSYATD.
    OrthoDBiEOG7RV9G2.
    PhylomeDBiP43007.
    TreeFamiTF315206.

    Family and domain databases

    Gene3Di1.10.3860.10. 2 hits.
    InterProiIPR001991. Na-dicarboxylate_symporter.
    IPR018107. Na-dicarboxylate_symporter_CS.
    [Graphical view]
    PANTHERiPTHR11958. PTHR11958. 1 hit.
    PfamiPF00375. SDF. 1 hit.
    [Graphical view]
    PRINTSiPR00173. EDTRNSPORT.
    SUPFAMiSSF118215. SSF118215. 2 hits.
    PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
    PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: P43007-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MEKSNETNGY LDSAQAGPAA GPGAPGTAAG RARRCAGFLR RQALVLLTVS    50
    GVLAGAGLGA ALRGLSLSRT QVTYLAFPGE MLLRMLRMII LPLVVCSLVS 100
    GAASLDASCL GRLGGIAVAY FGLTTLSASA LAVALAFIIK PGSGAQTLQS 150
    SDLGLEDSGP PPVPKETVDS FLDLARNLFP SNLVVAAFRT YATDYKVVTQ 200
    NSSSGNVTHE KIPIGTEIEG MNILGLVLFA LVLGVALKKL GSEGEDLIRF 250
    FNSLNEATMV LVSWIMWYVP VGIMFLVGSK IVEMKDIIVL VTSLGKYIFA 300
    SILGHVIHGG IVLPLIYFVF TRKNPFRFLL GLLAPFATAF ATCSSSATLP 350
    SMMKCIEENN GVDKRISRFI LPIGATVNMD GAAIFQCVAA VFIAQLNNVE 400
    LNAGQIFTIL VTATASSVGA AGVPAGGVLT IAIILEAIGL PTHDLPLILA 450
    VDWIVDRTTT VVNVEGDALG AGILHHLNQK ATKKGEQELA EVKVEAIPNC 500
    KSEEETSPLV THQNPAGPVA SAPELESKES VL 532
    Length:532
    Mass (Da):55,723
    Last modified:November 1, 1995 - v1
    Checksum:i57925860042FCEB6
    GO
    Isoform 2 (identifier: P43007-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-220: Missing.
         267-345: WYVPVGIMFL...FATAFATCSS → C

    Note: No experimental confirmation available.

    Show »
    Length:234
    Mass (Da):24,620
    Checksum:i4478DAA139931DAB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti117 – 1171A → R in AAA02761. (PubMed:8101838)Curated
    Sequence conflicti127 – 1271S → T in AAA19438. (PubMed:8340364)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti37 – 371G → R.
    Corresponds to variant rs1064512 [ dbSNP | Ensembl ].
    VAR_011878
    Natural varianti399 – 3991V → I.
    Corresponds to variant rs759458 [ dbSNP | Ensembl ].
    VAR_011879

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 220220Missing in isoform 2. 1 PublicationVSP_042880Add
    BLAST
    Alternative sequencei267 – 34579WYVPV…ATCSS → C in isoform 2. 1 PublicationVSP_042881Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L14595 mRNA. Translation: AAA02761.1.
    L19444 mRNA. Translation: AAA19438.1.
    U05235
    , U05229, U05230, U05231, U05232, U05233, U05234 Genomic DNA. Translation: AAC51349.1.
    AK295687 mRNA. Translation: BAH12156.1.
    AC007386 Genomic DNA. Translation: AAF03519.1.
    CH471053 Genomic DNA. Translation: EAW99932.1.
    CH471053 Genomic DNA. Translation: EAW99933.1.
    BC026216 mRNA. Translation: AAH26216.1.
    BC072423 mRNA. Translation: AAH72423.1.
    CCDSiCCDS1879.1. [P43007-1]
    CCDS54362.1. [P43007-2]
    PIRiI37188.
    I55389.
    RefSeqiNP_001180422.1. NM_001193493.1. [P43007-2]
    NP_003029.2. NM_003038.4. [P43007-1]
    UniGeneiHs.654352.

    Genome annotation databases

    EnsembliENST00000234256; ENSP00000234256; ENSG00000115902. [P43007-1]
    ENST00000531327; ENSP00000431942; ENSG00000115902. [P43007-2]
    GeneIDi6509.
    KEGGihsa:6509.
    UCSCiuc002sdh.3. human. [P43007-1]
    uc010ypz.2. human. [P43007-2]

    Polymorphism databases

    DMDMi1173365.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L14595 mRNA. Translation: AAA02761.1 .
    L19444 mRNA. Translation: AAA19438.1 .
    U05235
    , U05229 , U05230 , U05231 , U05232 , U05233 , U05234 Genomic DNA. Translation: AAC51349.1 .
    AK295687 mRNA. Translation: BAH12156.1 .
    AC007386 Genomic DNA. Translation: AAF03519.1 .
    CH471053 Genomic DNA. Translation: EAW99932.1 .
    CH471053 Genomic DNA. Translation: EAW99933.1 .
    BC026216 mRNA. Translation: AAH26216.1 .
    BC072423 mRNA. Translation: AAH72423.1 .
    CCDSi CCDS1879.1. [P43007-1 ]
    CCDS54362.1. [P43007-2 ]
    PIRi I37188.
    I55389.
    RefSeqi NP_001180422.1. NM_001193493.1. [P43007-2 ]
    NP_003029.2. NM_003038.4. [P43007-1 ]
    UniGenei Hs.654352.

    3D structure databases

    ProteinModelPortali P43007.
    SMRi P43007. Positions 73-474.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 112400. 2 interactions.
    MINTi MINT-4656683.
    STRINGi 9606.ENSP00000234256.

    Chemistry

    BindingDBi P43007.
    DrugBanki DB00160. L-Alanine.

    Protein family/group databases

    TCDBi 2.A.23.3.1. the dicarboxylate/amino acid:cation (na(+) or h(+)) symporter (daacs) family.

    PTM databases

    PhosphoSitei P43007.

    Polymorphism databases

    DMDMi 1173365.

    Proteomic databases

    MaxQBi P43007.
    PaxDbi P43007.
    PeptideAtlasi P43007.
    PRIDEi P43007.

    Protocols and materials databases

    DNASUi 6509.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000234256 ; ENSP00000234256 ; ENSG00000115902 . [P43007-1 ]
    ENST00000531327 ; ENSP00000431942 ; ENSG00000115902 . [P43007-2 ]
    GeneIDi 6509.
    KEGGi hsa:6509.
    UCSCi uc002sdh.3. human. [P43007-1 ]
    uc010ypz.2. human. [P43007-2 ]

    Organism-specific databases

    CTDi 6509.
    GeneCardsi GC02P065216.
    HGNCi HGNC:10942. SLC1A4.
    HPAi CAB002757.
    HPA034963.
    HPA034964.
    MIMi 600229. gene.
    neXtProti NX_P43007.
    PharmGKBi PA35829.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG1301.
    HOGENOMi HOG000208776.
    HOVERGENi HBG000080.
    InParanoidi P43007.
    KOi K05615.
    OMAi FRSYATD.
    OrthoDBi EOG7RV9G2.
    PhylomeDBi P43007.
    TreeFami TF315206.

    Enzyme and pathway databases

    Reactomei REACT_13796. Amino acid transport across the plasma membrane.

    Miscellaneous databases

    GeneWikii SLC1A4.
    GenomeRNAii 6509.
    NextBioi 25311.
    PMAP-CutDB P43007.
    PROi P43007.
    SOURCEi Search...

    Gene expression databases

    Bgeei P43007.
    CleanExi HS_SLC1A4.
    Genevestigatori P43007.

    Family and domain databases

    Gene3Di 1.10.3860.10. 2 hits.
    InterProi IPR001991. Na-dicarboxylate_symporter.
    IPR018107. Na-dicarboxylate_symporter_CS.
    [Graphical view ]
    PANTHERi PTHR11958. PTHR11958. 1 hit.
    Pfami PF00375. SDF. 1 hit.
    [Graphical view ]
    PRINTSi PR00173. EDTRNSPORT.
    SUPFAMi SSF118215. SSF118215. 2 hits.
    PROSITEi PS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
    PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family."
      Arriza J.L., Kavanaugh M.P., Fairman W.A., Wu Y.-N., Murdoch G.H., North R.A., Amara S.G.
      J. Biol. Chem. 268:15329-15332(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Tissue: Brain cortex.
    2. "Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters."
      Shafqat S., Tamarappoo B.K., Kilberg M.S., Puranam R.S., McNamara J.O., Guadano-Ferraz A., Fremeau R.T. Jr.
      J. Biol. Chem. 268:15351-15355(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Tissue: Hippocampus.
    3. "Human neutral amino acid transporter ASCT1: structure of the gene (SLC1A4) and localization to chromosome 2p13-p15."
      Hofmann K., Dueker M., Fink T., Lichter P., Stoffel W.
      Genomics 24:20-26(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Tissue: Placenta.
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Hippocampus.
    5. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Lymph and PNS.
    8. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
      Tissue: Melanoma.
    9. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-507, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    10. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.
      Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-201 AND ASN-206.
      Tissue: Leukemic T-cell.
    11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    13. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    14. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiSATT_HUMAN
    AccessioniPrimary (citable) accession number: P43007
    Secondary accession number(s): B7Z3C0, D6W5F0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 136 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 2
      Human chromosome 2: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

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