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P42950 (GSM1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose starvation modulator protein 1
Gene names
Name:GSM1
Ordered Locus Names:YJL103C
ORF Names:J0824
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length618 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Transcription factor which regulates nonfermentable carbon utilization By similarity. Binds specifically to 5'-CGGN8CGG-3' and 5'-CGGN9CGG-3' sequences in the promoter region. Ref.5

Subcellular location

Nucleus Probable.

Sequence similarities

Belongs to the ERT1/acuK family.

Contains 1 PAS (PER-ARNT-SIM) domain.

Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 618618Glucose starvation modulator protein 1
PRO_0000114998

Regions

Domain466 – 53873PAS
DNA binding20 – 4829Zn(2)-C6 fungal-type Ref.6 Ref.7

Experimental info

Sequence conflict6111F → L in AAU09751. Ref.4

Sequences

Sequence LengthMass (Da)Tools
P42950 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 200F6AEE06582E38

FASTA61870,382
        10         20         30         40         50         60 
MTKKLPSELK QTRKSIQTAC EFCHTKHIQC DVGRPCQNCL KRNIGKFCRD KKRKSRKRIE 

        70         80         90        100        110        120 
KHGTQPYLNL GKRLVIHDVP SKTVSPSSVH LQRDFLSSDQ EKPGKTPAHN TNIQYTYNIN 

       130        140        150        160        170        180 
DNFQSAGSIP RITNFNTNNR QTVLENTSNN ISASQAVHLM NDPIIPTVRK STLNLKSHFL 

       190        200        210        220        230        240 
EQHKAMQQPL ATNCLVATSN VPVHSGMDDS NKSDDDVDDE TNIHFDSMWC NDEYMKLKDI 

       250        260        270        280        290        300 
VDISTPFLPN NSQIFSLQES EYPNPSASTR GNSSLHLTNL LNSTKSVNDQ KDSSIGHSTS 

       310        320        330        340        350        360 
TFNTYDEVVS RPFISLDMLH LNRGANANTH PSHNAKLESE CDSSSHSDAD LEKHDTDFIS 

       370        380        390        400        410        420 
PSKFRELVKT PQDLYDNKCL IKPHNYKLAY TKLLTTLRKK FLEGAEIDKS ASVKDEHSTQ 

       430        440        450        460        470        480 
KHNLRYDLEV IIRSILERYA PIFISLTSNM IEEDLLLQEV TLQRALLDLE NMAKLVSCTP 

       490        500        510        520        530        540 
MCIWRRSGEI CFVSNEFYSL TGFNKNLLLD RTSFIFEYLD HKSVSNYFQI FNELLAFGYN 

       550        560        570        580        590        600 
DINKRKKLLM LNACSSTSSK ITEGFSFTTD GKAIFTKCNL LLSNGLYLKC ACCWTVKRDS 

       610 
FNIPILVMGQ FLPIFEMD 

« Hide

References

« Hide 'large scale' references
[1]"A 37.5 kb region of yeast chromosome X includes the SME1, MEF2, GSH1 and CSD3 genes, a TCP-1-related gene, an open reading frame similar to the DAL80 gene, and a tRNA(Arg)."
Rasmussen S.W.
Yeast 11:873-883(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[2]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Computationally analyzing the possible biological function of YJL103C--an ORF potentially involved in the regulation of energy process in yeast."
Deng Y., He T., Wu Y., Vanka P., Yang G., Huang Y., Yao H., Brown S.J.
Int. J. Mol. Med. 15:123-127(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: PREDICTION OF FUNCTION.
[6]"Linking DNA-binding proteins to their recognition sequences by using protein microarrays."
Ho S.-W., Jona G., Chen C.T.L., Johnston M., Snyder M.
Proc. Natl. Acad. Sci. U.S.A. 103:9940-9945(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: DNA-BINDING.
[7]"Improved genome-wide localization by ChIP-chip using double-round T7 RNA polymerase-based amplification."
van Bakel H., van Werven F.J., Radonjic M., Brok M.O., van Leenen D., Holstege F.C.P., Timmers H.T.M.
Nucleic Acids Res. 36:E21-E21(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: DNA-BINDING.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X85021 Genomic DNA. Translation: CAA59391.1.
Z49378 Genomic DNA. Translation: CAA89398.1.
AY723834 Genomic DNA. Translation: AAU09751.1.
BK006943 Genomic DNA. Translation: DAA08697.1.
PIRS53384.
RefSeqNP_012432.1. NM_001181536.1.

3D structure databases

ProteinModelPortalP42950.
SMRP42950. Positions 18-50.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33653. 17 interactions.
IntActP42950. 2 interactions.
STRING4932.YJL103C.

Proteomic databases

PaxDbP42950.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJL103C; YJL103C; YJL103C.
GeneID853341.
KEGGsce:YJL103C.

Organism-specific databases

CYGDYJL103c.
SGDS000003639. GSM1.

Phylogenomic databases

eggNOGNOG48118.
GeneTreeENSGT00530000068325.
HOGENOMHOG000141759.
OMAFIMELMY.
OrthoDBEOG70KGZB.

Enzyme and pathway databases

BioCycYEAST:G3O-31557-MONOMER.

Gene expression databases

GenevestigatorP42950.

Family and domain databases

Gene3D4.10.240.10. 1 hit.
InterProIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMSSF57701. SSF57701. 1 hit.
PROSITEPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio973727.

Entry information

Entry nameGSM1_YEAST
AccessionPrimary (citable) accession number: P42950
Secondary accession number(s): D6VW81, Q66R68
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families