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Protein

Probable fimbrial chaperone YraI

Gene

yraI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Part of the yraHIJK fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim operon.1 Publication

Miscellaneous

The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.1 Publication

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processFimbrium biogenesis

Enzyme and pathway databases

BioCyciEcoCyc:G7638-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable fimbrial chaperone YraI
Gene namesi
Name:yraI
Ordered Locus Names:b3143, JW3112
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12774 yraI

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

Pathology & Biotechi

Disruption phenotypei

Deletion of the operon under classical laboratory conditions does not result in any major effect on E.coli capacity to form biofilms compared with the wild-type strain.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000000929725 – 231Probable fimbrial chaperone YraIAdd BLAST207

Proteomic databases

PaxDbiP42914
PRIDEiP42914

Expressioni

Inductioni

Expression is negatively regulated by H-NS and subjected to cAMP receptor protein (CRP)-mediated catabolite repression.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4261996, 20 interactors
IntActiP42914, 5 interactors
STRINGi316385.ECDH10B_3316

Structurei

3D structure databases

ProteinModelPortaliP42914
SMRiP42914
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the periplasmic pilus chaperone family.Curated

Keywords - Domaini

Immunoglobulin domain, Signal

Phylogenomic databases

eggNOGiENOG4108VCD Bacteria
ENOG4111N65 LUCA
HOGENOMiHOG000260152
InParanoidiP42914
OMAiWEAINDY
PhylomeDBiP42914

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR008962 PapD-like_sf
IPR036316 Pili_assmbl_chap_C_dom_sf
IPR001829 Pili_assmbl_chaperone_bac
IPR016148 Pili_assmbl_chaperone_C
IPR018046 Pili_assmbl_chaperone_CS
IPR016147 Pili_assmbl_chaperone_N
PfamiView protein in Pfam
PF02753 PapD_C, 1 hit
PF00345 PapD_N, 1 hit
PRINTSiPR00969 CHAPERONPILI
SUPFAMiSSF49354 SSF49354, 1 hit
SSF49584 SSF49584, 1 hit
PROSITEiView protein in PROSITE
PS00635 PILI_CHAPERONE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P42914-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKRTFAVIL TLLCSFCIGQ ALAGGIVLQR TRVIYDASRK EAALPVANKG
60 70 80 90 100
AETPYLLQSW VDNIDGKSRA PFIITPPLFR LEAGDDSSLR IIKTADNLPE
110 120 130 140 150
NKESLFYINV RAIPAKKKSD DVNANELTLV FKTRIKMFYR PAHLKGRVND
160 170 180 190 200
AWKSLEFKRS DHSLNIYNPT EYYVVFAGLA VDKTDLTSKI EYIAPGEHKQ
210 220 230
LPLPASGGKN VKWAAINDYG GSSGTETRPL Q
Length:231
Mass (Da):25,677
Last modified:November 1, 1995 - v1
Checksum:i2416AC160661DE1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA Translation: AAA57946.1
U00096 Genomic DNA Translation: AAC76177.1
AP009048 Genomic DNA Translation: BAE77189.1
PIRiC65104
RefSeqiNP_417612.1, NC_000913.3
WP_000044775.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76177; AAC76177; b3143
BAE77189; BAE77189; BAE77189
GeneIDi947657
KEGGiecj:JW3112
eco:b3143
PATRICifig|1411691.4.peg.3587

Similar proteinsi

Entry informationi

Entry nameiYRAI_ECOLI
AccessioniPrimary (citable) accession number: P42914
Secondary accession number(s): Q2M967
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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