Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative N-acetylgalactosamine permease IIC component 2

Gene

agaW

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein uncertaini

Functioni

The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in N-acetylgalactosamine transport.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Phosphotransferase system, Sugar transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7633-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative N-acetylgalactosamine permease IIC component 2
Alternative name(s):
EIIC-Aga'
PTS system N-acetylgalactosamine-specific EIIC component 2
Gene namesi
Name:agaW
Ordered Locus Names:b3134
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12765. agaW.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 22CytoplasmicSequence analysis
Transmembranei3 – 2321HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini24 – 329PeriplasmicSequence analysis
Transmembranei33 – 5321HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini54 – 6512CytoplasmicSequence analysisAdd
BLAST
Transmembranei66 – 8621HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini87 – 937PeriplasmicSequence analysis
Transmembranei94 – 11421HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini115 – 13319CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 133133Putative N-acetylgalactosamine permease IIC component 2PRO_0000186661Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP42905.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 133133PTS EIIC type-4PROSITE-ProRule annotationAdd
BLAST

Domaini

The EIIC domain forms the PTS system translocation channel and contains the specific substrate-binding site.

Sequence similaritiesi

Contains 1 PTS EIIC type-4 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000202513.

Family and domain databases

InterProiIPR004700. PTS_IIC_sorb.
[Graphical view]
PfamiPF03609. EII-Sor. 1 hit.
[Graphical view]
PROSITEiPS51106. PTS_EIIC_TYPE_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42905-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEISLLQAFA LGIIAFIAGL DMFNGLTHMH RPVVLGPLVG LVLGDLHTGI
60 70 80 90 100
LTGGTLELVW MGLAPLAGAQ PPNVIIGTIV GTAFAITTGV KPDVAVGVAV
110 120 130
PFAVAVQMGI TFLFSVMSGV MSRCDLATNP RRI
Length:133
Mass (Da):13,721
Last modified:November 1, 1995 - v1
Checksum:i6F45186ABE8D7C38
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA57937.1.
U00096 Genomic DNA. No translation available.
PIRiB65103.
RefSeqiWP_000406204.1. NZ_LN832404.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA57937.1.
U00096 Genomic DNA. No translation available.
PIRiB65103.
RefSeqiWP_000406204.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP42905.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

EchoBASEiEB2618.
EcoGeneiEG12765. agaW.

Phylogenomic databases

HOGENOMiHOG000202513.

Enzyme and pathway databases

BioCyciEcoCyc:G7633-MONOMER.

Family and domain databases

InterProiIPR004700. PTS_IIC_sorb.
[Graphical view]
PfamiPF03609. EII-Sor. 1 hit.
[Graphical view]
PROSITEiPS51106. PTS_EIIC_TYPE_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPTPC2_ECOLI
AccessioniPrimary (citable) accession number: P42905
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: September 7, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.