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Protein

60S acidic ribosomal protein P2

Gene

RPLP2

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in the elongation step of protein synthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-BTA-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-BTA-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-BTA-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-BTA-72689. Formation of a pool of free 40S subunits.
R-BTA-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-BTA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-BTA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S acidic ribosomal protein P2
Gene namesi
Name:RPLP2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 29

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001576381 – 11560S acidic ribosomal protein P2Add BLAST115

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Modified residuei17PhosphoserineBy similarity1
Modified residuei19PhosphoserineBy similarity1
Modified residuei21N6-acetyllysine; alternateBy similarity1
Modified residuei21N6-succinyllysine; alternateBy similarity1
Modified residuei79PhosphoserineBy similarity1
Modified residuei86PhosphoserineBy similarity1
Modified residuei102PhosphoserineBy similarity1
Modified residuei105PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiP42899.
PeptideAtlasiP42899.
PRIDEiP42899.

Expressioni

Gene expression databases

BgeeiENSBTAG00000001777.

Interactioni

Subunit structurei

Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000002326.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3449. Eukaryota.
COG2058. LUCA.
GeneTreeiENSGT00550000074828.
HOGENOMiHOG000229897.
HOVERGENiHBG014761.
InParanoidiP42899.
KOiK02943.
OMAiAFFNFTM.
OrthoDBiEOG091G14BD.
TreeFamiTF320650.

Family and domain databases

HAMAPiMF_01478. Ribosomal_L12_arch. 1 hit.
InterProiView protein in InterPro
IPR027534. Ribosomal_L12.

Sequencei

Sequence statusi: Complete.

P42899-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYVASYLLA ALGGNSSPSA KDIKKILDSV GIEADDDRLN KVISELHGKN
60 70 80 90 100
IEDVIAQGIG KLASVPAGGA VAVSAAPGSA APAAGSAPAA AEEKKEEKKE
110
ESEESDDDMG FGLFD
Length:115
Mass (Da):11,702
Last modified:November 1, 1995 - v1
Checksum:i5C72FE24CE72F6BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17836 mRNA. Translation: AAC48755.1.
BC110143 mRNA. Translation: AAI10144.1.
RefSeqiNP_777213.1. NM_174788.4.
UniGeneiBt.5346.

Genome annotation databases

EnsembliENSBTAT00000002326; ENSBTAP00000002326; ENSBTAG00000001777.
GeneIDi286853.
KEGGibta:286853.

Similar proteinsi

Entry informationi

Entry nameiRLA2_BOVIN
AccessioniPrimary (citable) accession number: P42899
Secondary accession number(s): Q2YDN3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: September 27, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families