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Protein

Glucose-6-phosphate isomerase, cytosolic B

Gene

Os06g0256500

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathway:iglycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (Os06g0256500), Glucose-6-phosphate isomerase, Glucose-6-phosphate isomerase, Glucose-6-phosphate isomerase (OJ1113_A10.9), Glucose-6-phosphate isomerase (OsJ_27683), Glucose-6-phosphate isomerase, cytosolic A (Os03g0776000), Glucose-6-phosphate isomerase, cytosolic B (Os06g0256500), Glucose-6-phosphate isomerase, Glucose-6-phosphate isomerase (OJ1005_D12.17)
  3. ATP-dependent 6-phosphofructokinase (P0681D04.18), ATP-dependent 6-phosphofructokinase (P0014G10.8), ATP-dependent 6-phosphofructokinase (P0671B11.3), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (Os09g0415800), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (OSJNBb0021A09.36), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (Os10g0405600), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (P0529C07.30), ATP-dependent 6-phosphofructokinase (OSJNBa0016C11.39)
  4. Fructose-bisphosphate aldolase, chloroplastic (Os11g0171300), Fructose-bisphosphate aldolase (OsJ_21934), Fructose-bisphosphate aldolase, Fructose-bisphosphate aldolase (Os05g0402700), Fructose-bisphosphate aldolase (LOC_Os11g07020), Fructose-bisphosphate aldolase, Fructose-bisphosphate aldolase (B1203H11.11), Fructose-bisphosphate aldolase (OJ1134_E08.13), Fructose-bisphosphate aldolase (LOC_Os11g07020), Fructose-bisphosphate aldolase (LOC_Os11g07020), Fructose-bisphosphate aldolase (LOC_Os11g07020), Fructose-bisphosphate aldolase (P0556B08.18), Fructose-bisphosphate aldolase cytoplasmic isozyme (FBA), Fructose-bisphosphate aldolase (LOC_Os11g07020), Fructose-bisphosphate aldolase (LOC_Os10g08022), Fructose-bisphosphate aldolase (LOC_Os11g07020), Fructose-bisphosphate aldolase (P0494A10.15), Fructose-bisphosphate aldolase, Fructose-bisphosphate aldolase (LOC_Os11g07020), Fructose-bisphosphate aldolase (LOC_Os12g07210), Fructose-bisphosphate aldolase (B1417F08.1-2), Fructose-bisphosphate aldolase (B1417F08.1-1)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei360 – 3601Proton donorBy similarity
Active sitei391 – 3911By similarity
Active sitei516 – 5161By similarity

GO - Molecular functioni

  • glucose-6-phosphate isomerase activity Source: Gramene
  • isomerase activity Source: Gramene

GO - Biological processi

  • gluconeogenesis Source: Gramene
  • glycolytic process Source: Gramene
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

ReactomeiREACT_302664. Glycolysis.
REACT_339799. Gluconeogenesis.
REACT_360094. TP53 Regulates Metabolic Genes.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase, cytosolic B (EC:5.3.1.9)
Short name:
GPI-B
Alternative name(s):
Phosphoglucose isomerase B
Short name:
PGI-B
Phosphohexose isomerase B
Short name:
PHI-B
Gene namesi
Ordered Locus Names:Os06g0256500, LOC_Os06g14510
ORF Names:P0624H09.14
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 6

Organism-specific databases

GrameneiP42863.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: Gramene
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 567567Glucose-6-phosphate isomerase, cytosolic BPRO_0000180567Add
BLAST

Proteomic databases

PRIDEiP42863.

Expressioni

Gene expression databases

ExpressionAtlasiP42863. baseline.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi39947.LOC_Os06g14510.1.

Structurei

3D structure databases

ProteinModelPortaliP42863.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiCOG0166.
InParanoidiP42863.
KOiK01810.
OMAiISVMMAY.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42863-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSALICDT EQWKGLQAHV GAIQKTHLRD LMDDAERCKA MTAEYEGIFL
60 70 80 90 100
DYSRQRATGE TMEKLFKLAE AAKLKEKIEK MFSGDKINST ENRSVLHVAL
110 120 130 140 150
RAPRDEVIKS DGVNVVPEVW GVKDKIKQFS ETFRSGSWVG ATGKALTNVV
160 170 180 190 200
SVGIGGSFLG PLFVHAALQT DPEAAESAKG RQLRFLANVD PVDVARSIKD
210 220 230 240 250
LDPETTLVVV VSKTFTTAET MLNARTLKEW IVSSLGPDAV AKHMIAVSTN
260 270 280 290 300
LELVEKFGID PKNAFAFWDW VGGRYSVCSA VGVLPLSLQY GFPIVQKFLE
310 320 330 340 350
GAASIDKHFR SSSFEKNIPV LLGLLSVWNV SFLGYPARAI LPYSQALEKF
360 370 380 390 400
APHIQQLSME SNGKGVSIDG VQLSFETGEI DFGEPGTNGQ HSFYQLIHQG
410 420 430 440 450
RVIPCDFIGV VKSQQPVYLK GEIVSNHDEL MSNFFAQPDA LAYGKTPEQL
460 470 480 490 500
HSEKVPEHLI SHKTFQGNRP SLSLLLPSLS AYEIGQLLSI YEHRIAVQGF
510 520 530 540 550
LWGINSFDQW GVELGKSLAS QVRKSLHASR MEGKPVQGFN SSTASLLTRY
560
LAVEPSTPYN TTTMPKV
Length:567
Mass (Da):62,368
Last modified:March 7, 2006 - v2
Checksum:i57D56738888AE630
GO

Sequence cautioni

The sequence BAA08149.1 differs from that shown. Reason: Frameshift at positions 228 and 234. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti374 – 3741S → P in BAA08149 (PubMed:8722567).Curated
Sequence conflicti377 – 3771T → S in BAA08149 (PubMed:8722567).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D45218 mRNA. Translation: BAA08149.1. Frameshift.
AP005619 Genomic DNA. Translation: BAD46305.1.
PIRiT03950.
RefSeqiNP_001057316.1. NM_001063851.1.
UniGeneiOs.4697.

Genome annotation databases

GeneIDi4340677.
KEGGiosa:4340677.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D45218 mRNA. Translation: BAA08149.1. Frameshift.
AP005619 Genomic DNA. Translation: BAD46305.1.
PIRiT03950.
RefSeqiNP_001057316.1. NM_001063851.1.
UniGeneiOs.4697.

3D structure databases

ProteinModelPortaliP42863.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os06g14510.1.

Proteomic databases

PRIDEiP42863.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4340677.
KEGGiosa:4340677.

Organism-specific databases

GrameneiP42863.

Phylogenomic databases

eggNOGiCOG0166.
InParanoidiP42863.
KOiK01810.
OMAiISVMMAY.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
ReactomeiREACT_302664. Glycolysis.
REACT_339799. Gluconeogenesis.
REACT_360094. TP53 Regulates Metabolic Genes.

Gene expression databases

ExpressionAtlasiP42863. baseline.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of cDNA encoding for phosphoglucose isomerase of rice (Oryza sativa L.)."
    Nozue F., Umeda M., Nagamura Y., Minobe Y., Uchimiya H.
    DNA Seq. 6:127-135(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiG6PIB_ORYSJ
AccessioniPrimary (citable) accession number: P42863
Secondary accession number(s): Q652G2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: March 7, 2006
Last modified: June 24, 2015
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.