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Protein

Glucose-6-phosphate isomerase, cytosolic A

Gene

Os03g0776000

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei360 – 3601Proton donorBy similarity
Active sitei391 – 3911By similarity
Active sitei516 – 5161By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: Gramene
  2. isomerase activity Source: Gramene

GO - Biological processi

  1. gluconeogenesis Source: Gramene
  2. glycolytic process Source: Gramene
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

ReactomeiREACT_243951. Glycolysis.
REACT_254676. Gluconeogenesis.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase, cytosolic A (EC:5.3.1.9)
Short name:
GPI-A
Alternative name(s):
Phosphoglucose isomerase A
Short name:
PGI-A
Phosphohexose isomerase A
Short name:
PHI-A
Gene namesi
Ordered Locus Names:Os03g0776000, LOC_Os03g56460
ORF Names:OSJNBa0070N04.5
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 3

Organism-specific databases

GrameneiP42862.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Gramene
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 567567Glucose-6-phosphate isomerase, cytosolic APRO_0000180566Add
BLAST

Proteomic databases

PRIDEiP42862.

Expressioni

Gene expression databases

ExpressionAtlasiP42862. baseline.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP42862.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
InParanoidiP42862.
KOiK01810.
OMAiVERCKAM.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42862-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASSALICDT EQWKGLQAHV GEIQKTHLRH LMHDVERCKA MTAEYEGIYL
60 70 80 90 100
DYSRQRATGE TMEKLFKLAE AAKLKEKIEK MFRGDKINST ENRSVLHVAL
110 120 130 140 150
RAPRDEVINS NGVNVVPEVW GVKDKIKQFS ETFRSGSWVG ATGKALTNVV
160 170 180 190 200
SVGIGGSFLG PLFVHAALQT DPEAAESAKG RQLRFLANVD PVDVARSIKD
210 220 230 240 250
LDPETTLVVV VSKTFTTAET MLNARTLKEW IVSSLGPDAV AKHMIAVSTN
260 270 280 290 300
LELVEKFGID PKNAFAFWDW VGGRYSVCSA VGVLPLSLQY GFPIVQKFLE
310 320 330 340 350
GAASIDKHFR SSSFEKNIPV LLGLLSVWNV SFLGYPARAI LPYSQALEKF
360 370 380 390 400
APHIQQLSME SNGKGVSIDG VQLPFESGEI DFGEPGTNGQ HSFYQLIHQG
410 420 430 440 450
RVIPCDFIGV VKSQQPVYLK GEIVSNHDEL MSNFFAQPDA LAYGKTPEQL
460 470 480 490 500
HSEKVPEHLI PHKTFQGNRP SLSLLLPSLS AYEIGQLLAI YEHRIAVQGF
510 520 530 540 550
LWGINSFDQW GVELGKSLAS QVRKSLHASR VEGKPVLGFN SSTTSLLTRY
560
LAVEPSTPYN TTTLPKV
Length:567
Mass (Da):62,524
Last modified:March 7, 2006 - v2
Checksum:iE01202380A9A9C8E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti374 – 3741P → S in BAA08148. (PubMed:8722567)Curated
Sequence conflicti377 – 3771S → T in BAA08148. (PubMed:8722567)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D45217 mRNA. Translation: BAA08148.1.
AC091494 Genomic DNA. Translation: AAN65024.1.
PIRiT03948.
RefSeqiNP_001051434.1. NM_001057969.1.
UniGeneiOs.154.

Genome annotation databases

EnsemblPlantsiOS03T0776000-01; OS03T0776000-01; OS03G0776000.
GeneIDi4334290.
KEGGiosa:4334290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D45217 mRNA. Translation: BAA08148.1.
AC091494 Genomic DNA. Translation: AAN65024.1.
PIRiT03948.
RefSeqiNP_001051434.1. NM_001057969.1.
UniGeneiOs.154.

3D structure databases

ProteinModelPortaliP42862.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP42862.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS03T0776000-01; OS03T0776000-01; OS03G0776000.
GeneIDi4334290.
KEGGiosa:4334290.

Organism-specific databases

GrameneiP42862.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
InParanoidiP42862.
KOiK01810.
OMAiVERCKAM.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
ReactomeiREACT_243951. Glycolysis.
REACT_254676. Gluconeogenesis.

Gene expression databases

ExpressionAtlasiP42862. baseline.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of cDNA encoding for phosphoglucose isomerase of rice (Oryza sativa L.)."
    Nozue F., Umeda M., Nagamura Y., Minobe Y., Uchimiya H.
    DNA Seq. 6:127-135(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
    The rice chromosome 3 sequencing consortium
    Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S.
    , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
    Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiG6PIA_ORYSJ
AccessioniPrimary (citable) accession number: P42862
Secondary accession number(s): Q8H8M6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: March 7, 2006
Last modified: January 7, 2015
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.