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P42862 (G6PIA_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase, cytosolic A

Short name=GPI-A
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase A
Short name=PGI-A
Phosphohexose isomerase A
Short name=PHI-A
Gene names
Ordered Locus Names:Os03g0776000, LOC_Os03g56460
ORF Names:OSJNBa0070N04.5
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length567 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processdefense response to fungus, incompatible interaction

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

gluconeogenesis

Inferred from direct assay Ref.1. Source: Gramene

glycolysis

Inferred from direct assay Ref.1. Source: Gramene

response to cadmium ion

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentcytosol

Inferred from direct assay Ref.1. Source: Gramene

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from direct assay Ref.1. Source: Gramene

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 567567Glucose-6-phosphate isomerase, cytosolic A HAMAP-Rule MF_00473
PRO_0000180566

Sites

Active site3601Proton donor By similarity
Active site3911 By similarity
Active site5161 By similarity

Experimental info

Sequence conflict3741P → S in BAA08148. Ref.1
Sequence conflict3771S → T in BAA08148. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P42862 [UniParc].

Last modified March 7, 2006. Version 2.
Checksum: E01202380A9A9C8E

FASTA56762,524
        10         20         30         40         50         60 
MASSALICDT EQWKGLQAHV GEIQKTHLRH LMHDVERCKA MTAEYEGIYL DYSRQRATGE 

        70         80         90        100        110        120 
TMEKLFKLAE AAKLKEKIEK MFRGDKINST ENRSVLHVAL RAPRDEVINS NGVNVVPEVW 

       130        140        150        160        170        180 
GVKDKIKQFS ETFRSGSWVG ATGKALTNVV SVGIGGSFLG PLFVHAALQT DPEAAESAKG 

       190        200        210        220        230        240 
RQLRFLANVD PVDVARSIKD LDPETTLVVV VSKTFTTAET MLNARTLKEW IVSSLGPDAV 

       250        260        270        280        290        300 
AKHMIAVSTN LELVEKFGID PKNAFAFWDW VGGRYSVCSA VGVLPLSLQY GFPIVQKFLE 

       310        320        330        340        350        360 
GAASIDKHFR SSSFEKNIPV LLGLLSVWNV SFLGYPARAI LPYSQALEKF APHIQQLSME 

       370        380        390        400        410        420 
SNGKGVSIDG VQLPFESGEI DFGEPGTNGQ HSFYQLIHQG RVIPCDFIGV VKSQQPVYLK 

       430        440        450        460        470        480 
GEIVSNHDEL MSNFFAQPDA LAYGKTPEQL HSEKVPEHLI PHKTFQGNRP SLSLLLPSLS 

       490        500        510        520        530        540 
AYEIGQLLAI YEHRIAVQGF LWGINSFDQW GVELGKSLAS QVRKSLHASR VEGKPVLGFN 

       550        560 
SSTTSLLTRY LAVEPSTPYN TTTLPKV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D45217 mRNA. Translation: BAA08148.1.
AC091494 Genomic DNA. Translation: AAN65024.1.
PIRT03948.
RefSeqNP_001051434.1. NM_001057969.1.
UniGeneOs.154.

3D structure databases

ProteinModelPortalP42862.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP42862.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS03T0776000-01; OS03T0776000-01; OS03G0776000.
GeneID4334290.
KEGGosa:4334290.

Organism-specific databases

GrameneP42862.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMALKMHFVS.
ProtClustDBPLN02649.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Gene expression databases

ArrayExpressP42862.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PIA_ORYSJ
AccessionPrimary (citable) accession number: P42862
Secondary accession number(s): Q8H8M6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: March 7, 2006
Last modified: March 19, 2014
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways