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P42840 (YN60_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized membrane protein YNL320W
Gene names
Ordered Locus Names:YNL320W
ORF Names:N0342
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length284 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein.

Miscellaneous

Present with 259 molecules/cell in log phase SD medium.

Sequence similarities

To S.pombe bem46 and M.tuberculosis Rv2307c.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 284284Uncharacterized membrane protein YNL320W
PRO_0000203364

Regions

Topological domain1 – 88Cytoplasmic Potential
Transmembrane9 – 2517Helical; Potential
Topological domain26 – 8055Extracellular Potential
Transmembrane81 – 10121Helical; Potential
Topological domain102 – 284183Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P42840 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 933B35169A9CCCDA

FASTA28432,308
        10         20         30         40         50         60 
MLWKVSKMFL GGLVALTTIS VATLYHYQNR LVYPSWAQGA RNHVDTPDSR GIPYEKLTLI 

        70         80         90        100        110        120 
TQDHIKLEAW DIKNENSTST VLILCPNAGN IGYFILIIDI FYRQFGMSVF IYSYRGYGNS 

       130        140        150        160        170        180 
EGSPSEKGLK LDADCVISHL STDSFHSKRK LVLYGRSLGG ANALYIASKF RDLCDGVILE 

       190        200        210        220        230        240 
NTFLSIRKVI PYIFPLLKRF TLLCHEIWNS EGLMGSCSSE TPFLFLSGLK DEIVPPFHMR 

       250        260        270        280 
KLYETCPSSN KKIFEFPLGS HNDTIIQDGY WDIIRDFLIE KGFI 

« Hide

References

« Hide 'large scale' references
[1]"Sequencing analysis of a 24.7 kb fragment of yeast chromosome XIV identifies six known genes, a new member of the hexose transporter family and ten new open reading frames."
Maftahi M., Nicaud J.-M., Levesque H., Gaillardin C.
Yeast 11:1077-1085(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: S288c / FY1676.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. expand/collapse author list , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z46259 Genomic DNA. Translation: CAA86377.1.
Z71596 Genomic DNA. Translation: CAA96251.1.
BK006947 Genomic DNA. Translation: DAA10242.1.
PIRS51294.
RefSeqNP_014079.1. NM_001183158.1.

3D structure databases

ProteinModelPortalP42840.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35520. 5 interactions.
DIPDIP-4158N.
IntActP42840. 1 interaction.
MINTMINT-540401.
STRING4932.YNL320W.

Protein family/group databases

MEROPSS09.A35.

Proteomic databases

MaxQBP42840.
PaxDbP42840.
PeptideAtlasP42840.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYNL320W; YNL320W; YNL320W.
GeneID855396.
KEGGsce:YNL320W.

Organism-specific databases

CYGDYNL320w.
SGDS000005264. YNL320W.

Phylogenomic databases

eggNOGCOG1073.
GeneTreeENSGT00390000000948.
HOGENOMHOG000007143.
KOK06889.
OMAPEGTHND.
OrthoDBEOG7FZ097.

Enzyme and pathway databases

BioCycYEAST:G3O-33305-MONOMER.

Gene expression databases

GenevestigatorP42840.

Family and domain databases

Gene3D3.40.50.1820. 1 hit.
InterProIPR029058. AB_hydrolase.
IPR029059. AB_hydrolase_5.
[Graphical view]
PfamPF12695. Abhydrolase_5. 1 hit.
[Graphical view]
SUPFAMSSF53474. SSF53474. 1 hit.
ProtoNetSearch...

Other

NextBio979214.
PROP42840.

Entry information

Entry nameYN60_YEAST
AccessionPrimary (citable) accession number: P42840
Secondary accession number(s): D6W0M6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 11, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIV

Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD