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Protein

Extracellular subtilisin-like protease

Gene
N/A
Organism
Dichelobacter nodosus (Bacteroides nodosus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei171Charge relay systemBy similarity1
Active sitei237Charge relay systemBy similarity1
Active sitei409Charge relay systemBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine protease

Protein family/group databases

MEROPSiS08.023

Names & Taxonomyi

Protein namesi
Recommended name:
Extracellular subtilisin-like protease (EC:3.4.21.-)
OrganismiDichelobacter nodosus (Bacteroides nodosus)
Taxonomic identifieri870 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCardiobacterialesCardiobacteriaceaeDichelobacter

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
PropeptideiPRO_000002700122 – 130Sequence analysisAdd BLAST109
ChainiPRO_0000027002131 – 595Extracellular subtilisin-like proteaseAdd BLAST465

Keywords - PTMi

Zymogen

Proteomic databases

PRIDEiP42780

Structurei

3D structure databases

ProteinModelPortaliP42780
SMRiP42780
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini166 – 469Peptidase S8Add BLAST304
Domaini484 – 595P/Homo BPROSITE-ProRule annotationAdd BLAST112

Sequence similaritiesi

Belongs to the peptidase S8 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105RX7 Bacteria
COG1404 LUCA

Family and domain databases

CDDicd07496 Peptidases_S8_13, 1 hit
Gene3Di3.40.50.200, 1 hit
InterProiView protein in InterPro
IPR002884 P_dom
IPR000209 Peptidase_S8/S53_dom
IPR036852 Peptidase_S8/S53_dom_sf
IPR023827 Peptidase_S8_Asp-AS
IPR022398 Peptidase_S8_His-AS
IPR023828 Peptidase_S8_Ser-AS
IPR015500 Peptidase_S8_subtilisin-rel
IPR034176 Peptidases_S8_13
PfamiView protein in Pfam
PF01483 P_proprotein, 1 hit
PF00082 Peptidase_S8, 1 hit
PRINTSiPR00723 SUBTILISIN
SUPFAMiSSF52743 SSF52743, 2 hits
PROSITEiView protein in PROSITE
PS51829 P_HOMO_B, 1 hit
PS00136 SUBTILASE_ASP, 1 hit
PS00137 SUBTILASE_HIS, 1 hit
PS00138 SUBTILASE_SER, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P42780-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQSGINGVK TLTLVVCAAL ASQAYAAVNY ESANYIGSQP EGSVRFIIKY
60 70 80 90 100
KDKSQSQQMM TNRSTTSVMN NNNITIAGFN AQFVRTMTIG AGIFAVPDLK
110 120 130 140 150
TTKEAHLVMD TIASNPDVEY VEVDRWLRPF AAPNDPFYND QWHYYSEYGV
160 170 180 190 200
KADKVWDRGI TGKGVTVAVV DTGIVNHPDL NANVIPGSGY DFIQEAEIAQ
210 220 230 240 250
DGDGRDSNPA DAGDWHSNWA CGKYPDPRYE KRNSSWHGSH VAGTIAAVTN
260 270 280 290 300
NRIGVSGVAY DAKIVPVRVL GRCGGYNSDI NEGMYWAAGG HIDGVPDNKH
310 320 330 340 350
PAQVINMSLG GPGVCGSTEQ TLINRATQLG ATIIVAAGND NIDAYGVTPA
360 370 380 390 400
SCDNILTVGA TTSNGTRAYF SNHGSVVDIS APGAGITSTV DSGARYPSGP
410 420 430 440 450
SYSLMDGTSM ATPHVAGVAA LVISAANSVN KEMTPAQVRD VLVRTVSSFN
460 470 480 490 500
GTPDRRIGAG IVDADAAVNA VLDGNVVERP IDELKPQAEY RNPQIKLIRD
510 520 530 540 550
YQMMFSEIKV NGRPGNTKFA VVKADIRHTD PSQLKLRLVS PKGYEYAVHY
560 570 580 590
DNIKNKSSEL ITFPRDEQMN GYWRLKIVDT KRGVTGYTRG WSVAF
Length:595
Mass (Da):64,137
Last modified:November 1, 1995 - v1
Checksum:i744EF9B53187442E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L08175 Genomic DNA Translation: AAA99869.1
RefSeqiWP_012030937.1, NZ_LGVW01000011.1

Genome annotation databases

PATRICifig|870.4.peg.318

Similar proteinsi

Entry informationi

Entry nameiBPRX_DICNO
AccessioniPrimary (citable) accession number: P42780
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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