SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P42769

- GSTF1_ARATH

UniProt

P42769 - GSTF1_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutathione S-transferase PM239X14

Gene
N/A
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Specifically catalyzes the conjugation of synthetic 1-chloro-2,4-ditrobenzene to GSH. Also functions as a glutathione peroxidase, converting linoleate oxidation products into their corresponding hydroxyacids. This enzyme may thus serve to protect the cell from oxygen toxicity as well as from exogenous toxins such as herbicides.1 Publication

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB-EC
  2. peroxidase activity Source: UniProtKB-KW

GO - Biological processi

  1. response to stress Source: UniProtKB-KW
  2. response to toxic substance Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase, Transferase

Keywords - Biological processi

Detoxification, Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase PM239X14 (EC:2.5.1.18)
Alternative name(s):
GST class-phi
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Subcellular locationi

Cytoplasmcytosol Inferred

GO - Cellular componenti

  1. cytosol Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 218218Glutathione S-transferase PM239X14PRO_0000185849Add
BLAST

Expressioni

Tissue specificityi

Expressed in vegetative rosettes.

Developmental stagei

Expressed up until the first flowering buds, after which, levels dramatically decrease.

Gene expression databases

GenevestigatoriP42769.

Structurei

3D structure databases

ProteinModelPortaliP42769.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 8584GST N-terminalAdd
BLAST
Domaini93 – 218126GST C-terminalAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni12 – 132Glutathione binding By similarity
Regioni41 – 422Glutathione binding By similarity
Regioni55 – 562Glutathione binding By similarity
Regioni69 – 702Glutathione binding By similarity

Sequence similaritiesi

Belongs to the GST superfamily. Phi family.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42769-1 [UniParc]FASTAAdd to Basket

« Hide

MVTVKLYGMA YSTCTKRVYT TAKEIGVDVK IVPVDLMKGE HKEPAYLDNY    50
HPFGVIPVLE DEDGTKIYES RAISRYLVAK YGKGSSLLPS PSDPKAYGLF 100
EQAASVEYSS FDPPASSLAY ERVFAGMRGL KTNEELAKKY VDTLNAKMDG 150
YERILSKQKY LAGNDFTLAD LFHLPYGAMV AQLEPTVLDS KPHVKAWWAA 200
SLRVIPGRLL RNSSKEFM 218
Length:218
Mass (Da):24,364
Last modified:November 1, 1995 - v1
Checksum:iC7E6B6EC5320C33A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X68304 mRNA. Translation: CAA48376.1.
PIRiS36835.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X68304 mRNA. Translation: CAA48376.1 .
PIRi S36835.

3D structure databases

ProteinModelPortali P42769.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

Genevestigatori P42769.

Family and domain databases

Gene3Di 1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProi IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view ]
SUPFAMi SSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEi PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A glutathione S-transferase with glutathione-peroxidase activity from Arabidopsis thaliana. Molecular cloning and functional characterization."
    Bartling D., Radzio R., Steiner U., Weiler E.W.
    Eur. J. Biochem. 216:579-586(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION.
    Strain: cv. Landsberg erecta.
    Tissue: Leaf.
  2. Erratum
    Bartling D., Radzio R., Steiner U., Weiler E.W.
    Eur. J. Biochem. 218:1096-1096(1993)
  3. "Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
    Wagner U., Edwards R., Dixon D.P., Mauch F.
    Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiGSTF1_ARATH
AccessioniPrimary (citable) accession number: P42769
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 19, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Caution

This protein probably does not originate from A.thaliana, rather it resemble fungal GTSs.

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi