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P42761

- GSTFA_ARATH

UniProt

P42761 - GSTFA_ARATH

Protein

Glutathione S-transferase F10

Gene

GSTF10

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 120 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC). May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.1 Publication

    Catalytic activityi

    RX + glutathione = HX + R-S-glutathione.

    GO - Molecular functioni

    1. copper ion binding Source: TAIR
    2. glutathione binding Source: TAIR
    3. glutathione transferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. response to cadmium ion Source: TAIR
    2. response to toxic substance Source: UniProtKB-KW
    3. response to water deprivation Source: TAIR
    4. toxin catabolic process Source: TAIR

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Detoxification, Stress response

    Enzyme and pathway databases

    BioCyciARA:AT2G30870-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutathione S-transferase F10 (EC:2.5.1.18)
    Short name:
    AtGSTF10
    Alternative name(s):
    AtGSTF4
    GST class-phi member 10
    Protein EARLY RESPONSE TO DEHYDRATION 13
    Gene namesi
    Name:GSTF10
    Synonyms:ERD13, GSTF4
    Ordered Locus Names:At2g30870
    ORF Names:F7F1.8
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 2

    Organism-specific databases

    TAIRiAT2G30870.

    Subcellular locationi

    Cytoplasmcytosol Curated

    GO - Cellular componenti

    1. apoplast Source: TAIR
    2. cell wall Source: TAIR
    3. chloroplast Source: TAIR
    4. cytoplasm Source: TAIR
    5. cytosol Source: TAIR
    6. plasma membrane Source: TAIR
    7. vacuole Source: TAIR

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Disruption phenotypei

    No visible phenotype, maybe due to the possible redundancy with GSTF9.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 215214Glutathione S-transferase F10PRO_0000185847Add
    BLAST

    Proteomic databases

    PaxDbiP42761.
    PRIDEiP42761.

    2D gel databases

    SWISS-2DPAGEP42761.

    Expressioni

    Tissue specificityi

    Expressed in roots, stems, floral buds, mature flowers and leaves.1 Publication

    Inductioni

    By dehydration stress, wounding, H2O2 and jasmonate, but not by growth regulators.2 Publications

    Gene expression databases

    ArrayExpressiP42761.
    GenevestigatoriP42761.

    Interactioni

    Subunit structurei

    Interacts with BAK1.1 Publication

    Protein-protein interaction databases

    IntActiP42761. 1 interaction.
    MINTiMINT-8068911.
    STRINGi3702.AT2G30870.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliP42761.
    SMRiP42761. Positions 8-214.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 8180GST N-terminalAdd
    BLAST
    Domaini88 – 215128GST C-terminalAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni39 – 402Glutathione bindingBy similarity
    Regioni52 – 532Glutathione bindingBy similarity
    Regioni65 – 662Glutathione bindingBy similarity

    Sequence similaritiesi

    Belongs to the GST superfamily. Phi family.Curated
    Contains 1 GST C-terminal domain.Curated
    Contains 1 GST N-terminal domain.Curated

    Phylogenomic databases

    eggNOGiCOG0625.
    HOGENOMiHOG000125746.
    InParanoidiP42761.
    KOiK00799.
    OMAiFTEYLVG.
    PhylomeDBiP42761.

    Family and domain databases

    Gene3Di1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProiIPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view]
    PfamiPF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEiPS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P42761-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVLTIYAPLF ASSKRAVVTL VEKGVSFETV NVDLMKGEQR QPEYLAIQPF    50
    GKIPVLVDGD YKIFESRAIM RYIAEKYRSQ GPDLLGKTIE ERGQVEQWLD 100
    VEATSYHPPL LALTLNIVFA PLMGFPADEK VIKESEEKLA EVLDVYEAQL 150
    SKNEYLAGDF VSLADLAHLP FTEYLVGPIG KAHLIKDRKH VSAWWDKISS 200
    RAAWKEVSAK YSLPV 215
    Length:215
    Mass (Da):24,230
    Last modified:January 23, 2007 - v3
    Checksum:i9A53C0AD19580C79
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D17673 mRNA. Translation: BAA04554.1.
    AC004669 Genomic DNA. Translation: AAC20721.1.
    CP002685 Genomic DNA. Translation: AEC08450.1.
    AY128398 mRNA. Translation: AAM91601.1.
    BT000077 mRNA. Translation: AAN15396.1.
    PIRiS39542.
    RefSeqiNP_180644.1. NM_128639.3.
    UniGeneiAt.58604.
    At.71298.

    Genome annotation databases

    EnsemblPlantsiAT2G30870.1; AT2G30870.1; AT2G30870.
    GeneIDi817637.
    KEGGiath:AT2G30870.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D17673 mRNA. Translation: BAA04554.1 .
    AC004669 Genomic DNA. Translation: AAC20721.1 .
    CP002685 Genomic DNA. Translation: AEC08450.1 .
    AY128398 mRNA. Translation: AAM91601.1 .
    BT000077 mRNA. Translation: AAN15396.1 .
    PIRi S39542.
    RefSeqi NP_180644.1. NM_128639.3.
    UniGenei At.58604.
    At.71298.

    3D structure databases

    ProteinModelPortali P42761.
    SMRi P42761. Positions 8-214.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P42761. 1 interaction.
    MINTi MINT-8068911.
    STRINGi 3702.AT2G30870.1-P.

    2D gel databases

    SWISS-2DPAGE P42761.

    Proteomic databases

    PaxDbi P42761.
    PRIDEi P42761.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT2G30870.1 ; AT2G30870.1 ; AT2G30870 .
    GeneIDi 817637.
    KEGGi ath:AT2G30870.

    Organism-specific databases

    TAIRi AT2G30870.

    Phylogenomic databases

    eggNOGi COG0625.
    HOGENOMi HOG000125746.
    InParanoidi P42761.
    KOi K00799.
    OMAi FTEYLVG.
    PhylomeDBi P42761.

    Enzyme and pathway databases

    BioCyci ARA:AT2G30870-MONOMER.

    Gene expression databases

    ArrayExpressi P42761.
    Genevestigatori P42761.

    Family and domain databases

    Gene3Di 1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProi IPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view ]
    Pfami PF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEi PS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of two cDNAs (ERD11 and ERD13) for dehydration-inducible genes that encode putative glutathione S-transferases in Arabidopsis thaliana L."
      Kiyosue T., Yamaguchi-Shinozaki K., Shinozaki K.
      FEBS Lett. 335:189-192(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Columbia.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Differential extraction and protein sequencing reveals major differences in patterns of primary cell wall proteins from plants."
      Robertson D., Mitchell G.P., Gilroy J.S., Gerrish C., Bolwell G.P., Slabas A.R.
      J. Biol. Chem. 272:15841-15848(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 2-7.
      Strain: cv. Landsberg erecta.
    6. "Drought regulation of GST8, encoding the Arabidopsis homologue of ParC/Nt107 glutathione transferase/peroxidase."
      Bianchi M.W., Roux C., Vartanian N.
      Physiol. Plantarum 116:96-105(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION.
    7. "Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
      Wagner U., Edwards R., Dixon D.P., Mauch F.
      Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, GENE FAMILY, NOMENCLATURE.
      Strain: cv. Columbia.
    8. "Modulations of AtGSTF10 expression induce stress tolerance and BAK1-mediated cell death."
      Ryu H.Y., Kim S.Y., Park H.M., You J.Y., Kim B.H., Lee J.S., Nam K.H.
      Biochem. Biophys. Res. Commun. 379:417-422(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY, INDUCTION BY GROWTH REGULATORS, DISRUPTION PHENOTYPE, INTERACTION WITH BAK1.

    Entry informationi

    Entry nameiGSTFA_ARATH
    AccessioniPrimary (citable) accession number: P42761
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 120 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3