Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutathione S-transferase F10

Gene

GSTF10

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC). May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.1 Publication

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  • copper ion binding Source: TAIR
  • glutathione binding Source: TAIR
  • glutathione transferase activity Source: GO_Central

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • response to cadmium ion Source: TAIR
  • response to water deprivation Source: TAIR
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification, Stress response

Enzyme and pathway databases

BioCyciARA:AT2G30870-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase F10 (EC:2.5.1.18)
Short name:
AtGSTF10
Alternative name(s):
AtGSTF4
GST class-phi member 10
Protein EARLY RESPONSE TO DEHYDRATION 13
Gene namesi
Name:GSTF10
Synonyms:ERD13, GSTF4
Ordered Locus Names:At2g30870
ORF Names:F7F1.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G30870
TAIRilocus:2052826 AT2G30870

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Disruption phenotypei

No visible phenotype, maybe due to the possible redundancy with GSTF9.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001858472 – 215Glutathione S-transferase F10Add BLAST214

Proteomic databases

PaxDbiP42761
PRIDEiP42761

2D gel databases

SWISS-2DPAGEP42761

PTM databases

iPTMnetiP42761

Expressioni

Tissue specificityi

Expressed in roots, stems, floral buds, mature flowers and leaves.1 Publication

Inductioni

By dehydration stress, wounding, H2O2 and jasmonate, but not by growth regulators.2 Publications

Gene expression databases

ExpressionAtlasiP42761 baseline and differential
GenevisibleiP42761 AT

Interactioni

Subunit structurei

Interacts with BAK1.1 Publication

Protein-protein interaction databases

BioGridi2986, 1 interactor
IntActiP42761, 1 interactor
STRINGi3702.AT2G30870.1

Structurei

3D structure databases

ProteinModelPortaliP42761
SMRiP42761
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 81GST N-terminalAdd BLAST80
Domaini88 – 215GST C-terminalAdd BLAST128

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni39 – 40Glutathione bindingBy similarity2
Regioni52 – 53Glutathione bindingBy similarity2
Regioni65 – 66Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Phi family.Curated

Phylogenomic databases

eggNOGiKOG0867 Eukaryota
COG0625 LUCA
HOGENOMiHOG000125746
InParanoidiP42761
KOiK00799
OMAiEENWAGA
OrthoDBiEOG09360M18
PhylomeDBiP42761

Family and domain databases

CDDicd03187 GST_C_Phi, 1 hit
InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR034347 GST_Phi_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P42761-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLTIYAPLF ASSKRAVVTL VEKGVSFETV NVDLMKGEQR QPEYLAIQPF
60 70 80 90 100
GKIPVLVDGD YKIFESRAIM RYIAEKYRSQ GPDLLGKTIE ERGQVEQWLD
110 120 130 140 150
VEATSYHPPL LALTLNIVFA PLMGFPADEK VIKESEEKLA EVLDVYEAQL
160 170 180 190 200
SKNEYLAGDF VSLADLAHLP FTEYLVGPIG KAHLIKDRKH VSAWWDKISS
210
RAAWKEVSAK YSLPV
Length:215
Mass (Da):24,230
Last modified:January 23, 2007 - v3
Checksum:i9A53C0AD19580C79
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D17673 mRNA Translation: BAA04554.1
AC004669 Genomic DNA Translation: AAC20721.1
CP002685 Genomic DNA Translation: AEC08450.1
AY128398 mRNA Translation: AAM91601.1
BT000077 mRNA Translation: AAN15396.1
PIRiS39542
RefSeqiNP_180644.1, NM_128639.4
UniGeneiAt.58604
At.71298

Genome annotation databases

EnsemblPlantsiAT2G30870.1; AT2G30870.1; AT2G30870
GeneIDi817637
GrameneiAT2G30870.1; AT2G30870.1; AT2G30870
KEGGiath:AT2G30870

Similar proteinsi

Entry informationi

Entry nameiGSTFA_ARATH
AccessioniPrimary (citable) accession number: P42761
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: April 25, 2018
This is version 146 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health