Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P42757 (BADH_ATRHO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase, chloroplastic

Short name=BADH
EC=1.2.1.8
OrganismAtriplex hortensis (Mountain spinach)
Taxonomic identifier34272 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesAmaranthaceaeChenopodioideaeAtripliceaeAtriplex

Protein attributes

Sequence length502 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH.

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1.

Subunit structure

Homodimer By similarity.

Subcellular location

Plastidchloroplast.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   Cellular componentChloroplast
Plastid
   DomainTransit peptide
   LigandNAD
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processglycine betaine biosynthetic process from choline

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 77Chloroplast Potential
Chain8 – 502495Betaine aldehyde dehydrogenase, chloroplastic
PRO_0000007180

Regions

Nucleotide binding240 – 2456NAD By similarity

Sites

Active site2621Proton acceptor By similarity
Active site2961Nucleophile By similarity
Site1641Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
P42757 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 54F1A05EBBC4281E

FASTA50255,271
        10         20         30         40         50         60 
MAFPIPARQL FIDGEWREPL LKNRIPIINP STEEIIGDIP AATAEDVEVA VVAARKAFKR 

        70         80         90        100        110        120 
NKGRDWAALW SHRAKYLRAI AAKITEKKDH FVKLETLDSG KPRDEAVLDI DDVATCFEYF 

       130        140        150        160        170        180 
EYFAGQAEAL DAKQKAPVTL PMERFKSHVL RQPIGVVGLI SPWNYPLLMD TWKIAPALAA 

       190        200        210        220        230        240 
GCTTVLKPSE LASVTCLEFG EVCNEVGLPP GVLNILTGLG PDAGAPIVSH PDIDKVAFTG 

       250        260        270        280        290        300 
SSATGSKIMA SAAQLVKPVT LELGGKSPVI MFEDIDIETA VEWTLFGVFW TNGQICSATS 

       310        320        330        340        350        360 
RLLVHESIAA EFVDRMVKWT KNIKISDPFE EGCRLGPVIS KGQYDKIMKF ISTAKSEGAT 

       370        380        390        400        410        420 
ILCGGSRPEH LKKGYYIEPT IITDITTSMQ IWKEEVFGPV ICVKTFKTED EAIELANDTE 

       430        440        450        460        470        480 
YGLAGAVFSK DLERCERVTK ALEVGAVWVN CSQPCFVHAP WGGVKRSGFG RELGEWGIEN 

       490        500 
YLNIKQVTSD ISDEPWGWYK SP 

« Hide

References

[1]"cDNA and partial genomic DNA sequence of Mountain spinach (Atriplex hortenis) betaine aldehyde dehydrogenase (BADH)."
Xiao G., Zhang G., Liu F., Chen S.
Chin. Sci. Bull. 40:741-745(1995)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
Tissue: Leaf and Stem.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X69770 mRNA. Translation: CAA49425.1.
X69772 Genomic DNA. Translation: CAA49427.1.
PIRS49205.

3D structure databases

ProteinModelPortalP42757.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00529; UER00386.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. SSF53720. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBADH_ATRHO
AccessionPrimary (citable) accession number: P42757
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 19, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways