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Protein

Cyclin-D1-1

Gene

CYCD1-1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May activate cell cycle in the root apical meristem (RAM) and promote embryonic root (radicle) protrusion.1 Publication

GO - Biological processi

Keywordsi

Molecular functionCyclin
Biological processCell cycle, Cell division

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-D1-1
Alternative name(s):
Cyclin-delta-1
Short name:
Cyclin-d1
G1/S-specific cyclin-D1-1
Short name:
CycD1;1
Gene namesi
Name:CYCD1-1
Synonyms:CYCD1
Ordered Locus Names:At1g70210
ORF Names:F20P5.7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRilocus:2020663. AT1G70210.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000804451 – 339Cyclin-D1-1Add BLAST339

Proteomic databases

PaxDbiP42751.

Expressioni

Tissue specificityi

Expressed in roots, leaves and flowers.1 Publication

Developmental stagei

Transiently expressed in the root tip during seed germination up to about 21 hours after stratification.1 Publication

Gene expression databases

GenevisibleiP42751. AT.

Interactioni

Subunit structurei

Interacts with CDKA-1 and KRP6/ICK4.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
CDKB2-1Q8LF802EBI-2025690,EBI-1253579

Protein-protein interaction databases

BioGridi28578. 13 interactors.
IntActiP42751. 4 interactors.
STRINGi3702.AT1G70210.1.

Structurei

3D structure databases

ProteinModelPortaliP42751.
SMRiP42751.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclin family. Cyclin D subfamily.Curated

Phylogenomic databases

eggNOGiKOG0656. Eukaryota.
ENOG410XRKC. LUCA.
HOGENOMiHOG000242458.
InParanoidiP42751.
KOiK18810.
OMAiFFISHAT.
OrthoDBiEOG09360FYD.
PhylomeDBiP42751.

Family and domain databases

Gene3Di1.10.472.10. 2 hits.
InterProiView protein in InterPro
IPR013763. Cyclin-like.
IPR004367. Cyclin_C-dom.
IPR006671. Cyclin_N.
IPR011031. Multihaem_cyt.
PfamiView protein in Pfam
PF02984. Cyclin_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
SMARTiView protein in SMART
SM00385. CYCLIN. 1 hit.
SM01332. Cyclin_C. 1 hit.
SUPFAMiSSF47954. SSF47954. 1 hit.
SSF48695. SSF48695. 1 hit.
PROSITEiView protein in PROSITE
PS00292. CYCLINS. 1 hit.

Sequencei

Sequence statusi: Complete.

P42751-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSYRFSDYL HMSVSFSNDM DLFCGEDSGV FSGESTVDFS SSEVDSWPGD
60 70 80 90 100
SIACFIEDER HFVPGHDYLS RFQTRSLDAS AREDSVAWIL KVQAYYNFQP
110 120 130 140 150
LTAYLAVNYM DRFLYARRLP ETSGWPMQLL AVACLSLAAK MEEILVPSLF
160 170 180 190 200
DFQVAGVKYL FEAKTIKRME LLVLSVLDWR LRSVTPFDFI SFFAYKIDPS
210 220 230 240 250
GTFLGFFISH ATEIILSNIK EASFLEYWPS SIAAAAILCV ANELPSLSSV
260 270 280 290 300
VNPHESPETW CDGLSKEKIV RCYRLMKAMA IENNRLNTPK VIAKLRVSVR
310 320 330
ASSTLTRPSD ESSFSSSSPC KRRKLSGYSW VGDETSTSN
Length:339
Mass (Da):38,277
Last modified:February 15, 2005 - v3
Checksum:i65D2449D5DBCE9D6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti314 – 317Missing in CAA58285 (PubMed:7696881).Curated4

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X83369 mRNA. Translation: CAA58285.1.
AC002062 Genomic DNA. Translation: AAB61096.1.
CP002684 Genomic DNA. Translation: AEE35034.1.
AK117189 mRNA. Translation: BAC41865.1.
BT005315 mRNA. Translation: AAO63379.1.
AF208693 Genomic DNA. Translation: AAL35986.1.
PIRiA96725.
S51650.
RefSeqiNP_177178.1. NM_105689.4.
UniGeneiAt.10298.

Genome annotation databases

EnsemblPlantsiAT1G70210.1; AT1G70210.1; AT1G70210.
GeneIDi843357.
GrameneiAT1G70210.1; AT1G70210.1; AT1G70210.
KEGGiath:AT1G70210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X83369 mRNA. Translation: CAA58285.1.
AC002062 Genomic DNA. Translation: AAB61096.1.
CP002684 Genomic DNA. Translation: AEE35034.1.
AK117189 mRNA. Translation: BAC41865.1.
BT005315 mRNA. Translation: AAO63379.1.
AF208693 Genomic DNA. Translation: AAL35986.1.
PIRiA96725.
S51650.
RefSeqiNP_177178.1. NM_105689.4.
UniGeneiAt.10298.

3D structure databases

ProteinModelPortaliP42751.
SMRiP42751.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi28578. 13 interactors.
IntActiP42751. 4 interactors.
STRINGi3702.AT1G70210.1.

Proteomic databases

PaxDbiP42751.

Protocols and materials databases

DNASUi843357.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G70210.1; AT1G70210.1; AT1G70210.
GeneIDi843357.
GrameneiAT1G70210.1; AT1G70210.1; AT1G70210.
KEGGiath:AT1G70210.

Organism-specific databases

AraportiAT1G70210.
TAIRilocus:2020663. AT1G70210.

Phylogenomic databases

eggNOGiKOG0656. Eukaryota.
ENOG410XRKC. LUCA.
HOGENOMiHOG000242458.
InParanoidiP42751.
KOiK18810.
OMAiFFISHAT.
OrthoDBiEOG09360FYD.
PhylomeDBiP42751.

Miscellaneous databases

PROiP42751.

Gene expression databases

GenevisibleiP42751. AT.

Family and domain databases

Gene3Di1.10.472.10. 2 hits.
InterProiView protein in InterPro
IPR013763. Cyclin-like.
IPR004367. Cyclin_C-dom.
IPR006671. Cyclin_N.
IPR011031. Multihaem_cyt.
PfamiView protein in Pfam
PF02984. Cyclin_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
SMARTiView protein in SMART
SM00385. CYCLIN. 1 hit.
SM01332. Cyclin_C. 1 hit.
SUPFAMiSSF47954. SSF47954. 1 hit.
SSF48695. SSF48695. 1 hit.
PROSITEiView protein in PROSITE
PS00292. CYCLINS. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCCD11_ARATH
AccessioniPrimary (citable) accession number: P42751
Secondary accession number(s): O04525, Q8W2K2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: February 15, 2005
Last modified: February 15, 2017
This is version 119 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.