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Protein

14-3-3-like protein GF14 upsilon

Gene

GRF5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes. May be involved in cell cycle regulation by binding to soluble EDE1 and sequestering it in an inactive form during the early stages of mitosis.1 Publication

GO - Molecular functioni

  • ATP binding Source: TAIR
  • protein domain specific binding Source: InterPro

GO - Biological processi

  • response to cadmium ion Source: TAIR

Enzyme and pathway databases

ReactomeiR-ATH-1445148 Translocation of GLUT4 to the plasma membrane
R-ATH-3371453 Regulation of HSF1-mediated heat shock response
R-ATH-3371511 HSF1 activation

Names & Taxonomyi

Protein namesi
Recommended name:
14-3-3-like protein GF14 upsilon
Alternative name(s):
General regulatory factor 5
Gene namesi
Name:GRF5
Ordered Locus Names:At5g16050
ORF Names:F1N13_190
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G16050
TAIRilocus:2146147 AT5G16050

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000586671 – 26814-3-3-like protein GF14 upsilonAdd BLAST268

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei69PhosphoserineBy similarity1
Modified residuei192PhosphoserineBy similarity1
Modified residuei213PhosphothreonineBy similarity1
Modified residuei267PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP42645
PRIDEiP42645

PTM databases

iPTMnetiP42645

Expressioni

Gene expression databases

ExpressionAtlasiP42645 baseline and differential
GenevisibleiP42645 AT

Interactioni

Subunit structurei

Interacts with EDE1 (PubMed:21558460). Interacts with DREB1A and DREB1B in the nucleus (PubMed:28344081).2 Publications

GO - Molecular functioni

Protein-protein interaction databases

BioGridi16738, 12 interactors
IntActiP42645, 6 interactors
MINTiP42645
STRINGi3702.AT5G16050.1

Structurei

3D structure databases

ProteinModelPortaliP42645
SMRiP42645
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 14-3-3 family.Curated

Phylogenomic databases

eggNOGiKOG0841 Eukaryota
COG5040 LUCA
HOGENOMiHOG000240379
KOiK06630
OMAiNSDHVSI
OrthoDBiEOG09360IZO
PhylomeDBiP42645

Family and domain databases

Gene3Di1.20.190.20, 1 hit
InterProiView protein in InterPro
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain
PANTHERiPTHR18860 PTHR18860, 1 hit
PfamiView protein in Pfam
PF00244 14-3-3, 1 hit
PIRSFiPIRSF000868 14-3-3, 1 hit
PRINTSiPR00305 1433ZETA
SMARTiView protein in SMART
SM00101 14_3_3, 1 hit
SUPFAMiSSF48445 SSF48445, 1 hit
PROSITEiView protein in PROSITE
PS00796 1433_1, 1 hit
PS00797 1433_2, 1 hit

Sequencei

Sequence statusi: Complete.

P42645-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDSSREEN VYLAKLAEQA ERYEEMVEFM EKVAKTVETE ELTVEERNLL
60 70 80 90 100
SVAYKNVIGA RRASWRIISS IEQKEDSRGN SDHVSIIKDY RGKIETELSK
110 120 130 140 150
ICDGILNLLE AHLIPAASLA ESKVFYLKMK GDYHRYLAEF KTGAERKEAA
160 170 180 190 200
ESTLVAYKSA QDIALADLAP THPIRLGLAL NFSVFYYEIL NSSDRACSLA
210 220 230 240 250
KQAFDEAISE LDTLGEESYK DSTLIMQLLR DNLTLWTSDL NDEAGDDIKE
260
APKEVQKVDE QAQPPPSQ
Length:268
Mass (Da):30,182
Last modified:October 1, 1996 - v2
Checksum:iECB35B7E53F688FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L09109 mRNA Translation: AAB06585.1
AF001415 Genomic DNA Translation: AAB62225.1
AL391145 Genomic DNA Translation: CAC01804.1
CP002688 Genomic DNA Translation: AED92241.1
CP002688 Genomic DNA Translation: ANM69323.1
AY035170 mRNA Translation: AAK59674.1
AY059115 mRNA Translation: AAL15221.1
PIRiS71173
T51388
RefSeqiNP_001331015.1, NM_001343435.1
NP_568325.1, NM_121610.4
UniGeneiAt.25563
At.64750

Genome annotation databases

EnsemblPlantsiAT5G16050.1; AT5G16050.1; AT5G16050
AT5G16050.2; AT5G16050.2; AT5G16050
GeneIDi831462
GrameneiAT5G16050.1; AT5G16050.1; AT5G16050
AT5G16050.2; AT5G16050.2; AT5G16050
KEGGiath:AT5G16050

Similar proteinsi

Entry informationi

Entry namei14335_ARATH
AccessioniPrimary (citable) accession number: P42645
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 1, 1996
Last modified: April 25, 2018
This is version 132 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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