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Protein

Pirin-like protein YhaK

Gene

yhaK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Does not have quercetin 2,3-dioxygenase activity.1 Publication

Miscellaneous

Contains Cys residues that are easily oxidized.

Caution

Lacks the conserved His residues required for metal binding. Its function must therefore be different from the metal-dependent roles proposed for other family members.Curated

Enzyme and pathway databases

BioCyciEcoCyc:G7620-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Pirin-like protein YhaK
Gene namesi
Name:yhaK
Ordered Locus Names:b3106, JW3077
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12750 yhaK

Subcellular locationi

  • Cytoplasm 1 Publication

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002140611 – 233Pirin-like protein YhaKAdd BLAST233

Proteomic databases

PaxDbiP42624
PRIDEiP42624

Interactioni

Subunit structurei

Monomer.1 Publication

Protein-protein interaction databases

BioGridi4259260, 11 interactors
IntActiP42624, 12 interactors
STRINGi316385.ECDH10B_3282

Structurei

Secondary structure

1233
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi11 – 13Combined sources3
Helixi17 – 19Combined sources3
Beta strandi22 – 25Combined sources4
Beta strandi40 – 48Combined sources9
Beta strandi53 – 57Combined sources5
Beta strandi60 – 77Combined sources18
Beta strandi82 – 86Combined sources5
Beta strandi89 – 93Combined sources5
Beta strandi101 – 105Combined sources5
Beta strandi108 – 110Combined sources3
Beta strandi112 – 120Combined sources9
Beta strandi129 – 134Combined sources6
Beta strandi138 – 147Combined sources10
Helixi149 – 151Combined sources3
Beta strandi156 – 158Combined sources3
Beta strandi160 – 166Combined sources7
Beta strandi171 – 175Combined sources5
Beta strandi177 – 188Combined sources12
Beta strandi190 – 194Combined sources5
Beta strandi197 – 202Combined sources6
Beta strandi207 – 212Combined sources6
Beta strandi214 – 231Combined sources18

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2VECX-ray1.85A2-233[»]
ProteinModelPortaliP42624
SMRiP42624
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP42624

Family & Domainsi

Sequence similaritiesi

Belongs to the pirin family.Curated

Phylogenomic databases

eggNOGiENOG4108CNN Bacteria
COG1741 LUCA
HOGENOMiHOG000114206
InParanoidiP42624
KOiK06911
OMAiTQPGISY
PhylomeDBiP42624

Family and domain databases

Gene3Di2.60.120.10, 2 hits
InterProiView protein in InterPro
IPR012093 Pirin
IPR003829 Pirin_N_dom
IPR014710 RmlC-like_jellyroll
IPR011051 RmlC_Cupin_sf
PfamiView protein in Pfam
PF02678 Pirin, 1 hit
PIRSFiPIRSF006232 Pirin, 1 hit
SUPFAMiSSF51182 SSF51182, 1 hit

Sequencei

Sequence statusi: Complete.

P42624-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITTRTARQC GQADYGWLQA RYTFSFGHYF DPKLLGYASL RVLNQEVLAP
60 70 80 90 100
GAAFQPRTYP KVDILNVILD GEAEYRDSEG NHVQASAGEA LLLSTQPGVS
110 120 130 140 150
YSEHNLSKDK PLTRMQLWLD ACPQRENPLI QKLALNMGKQ QLIASPEGAM
160 170 180 190 200
GSLQLRQQVW LHHIVLDKGE SANFQLHGPR AYLQSIHGKF HALTHHEEKA
210 220 230
ALTCGDGAFI RDEANITLVA DSPLRALLID LPV
Length:233
Mass (Da):25,895
Last modified:November 1, 1995 - v1
Checksum:i7C09B140A74E6B24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA Translation: AAA57910.1
U00096 Genomic DNA Translation: AAC76141.1
AP009048 Genomic DNA Translation: BAE77156.1
PIRiG65099
RefSeqiNP_417577.1, NC_000913.3
WP_000633576.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76141; AAC76141; b3106
BAE77156; BAE77156; BAE77156
GeneIDi947620
KEGGiecj:JW3077
eco:b3106
PATRICifig|1411691.4.peg.3622

Similar proteinsi

Entry informationi

Entry nameiYHAK_ECOLI
AccessioniPrimary (citable) accession number: P42624
Secondary accession number(s): Q2M9A0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

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