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Protein

Inner membrane transporter YgjI

Gene

ygjI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YGJI-MONOMER.
ECOL316407:JW5512-MONOMER.

Protein family/group databases

TCDBi2.A.3.7.4. the amino acid-polyamine-organocation (apc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane transporter YgjI
Gene namesi
Name:ygjI
Ordered Locus Names:b3078, JW5512
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12720. ygjI.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 8PeriplasmicSequence analysis8
Transmembranei9 – 29HelicalSequence analysisAdd BLAST21
Topological domaini30 – 41CytoplasmicSequence analysisAdd BLAST12
Transmembranei42 – 62HelicalSequence analysisAdd BLAST21
Topological domaini63 – 83PeriplasmicSequence analysisAdd BLAST21
Transmembranei84 – 104HelicalSequence analysisAdd BLAST21
Topological domaini105 – 120CytoplasmicSequence analysisAdd BLAST16
Transmembranei121 – 141HelicalSequence analysisAdd BLAST21
Topological domaini142 – 158PeriplasmicSequence analysisAdd BLAST17
Transmembranei159 – 179HelicalSequence analysisAdd BLAST21
Topological domaini180 – 196CytoplasmicSequence analysisAdd BLAST17
Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Topological domaini218 – 232PeriplasmicSequence analysisAdd BLAST15
Transmembranei233 – 253HelicalSequence analysisAdd BLAST21
Topological domaini254 – 263CytoplasmicSequence analysis10
Transmembranei264 – 284HelicalSequence analysisAdd BLAST21
Topological domaini285 – 286PeriplasmicSequence analysis2
Transmembranei287 – 307HelicalSequence analysisAdd BLAST21
Topological domaini308 – 335CytoplasmicSequence analysisAdd BLAST28
Transmembranei336 – 356HelicalSequence analysisAdd BLAST21
Topological domaini357 – 364PeriplasmicSequence analysis8
Transmembranei365 – 385HelicalSequence analysisAdd BLAST21
Topological domaini386 – 405CytoplasmicSequence analysisAdd BLAST20
Transmembranei406 – 426HelicalSequence analysisAdd BLAST21
Topological domaini427 – 431PeriplasmicSequence analysis5
Transmembranei432 – 452HelicalSequence analysisAdd BLAST21
Topological domaini453 – 477CytoplasmicSequence analysisAdd BLAST25

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002130451 – 477Inner membrane transporter YgjIAdd BLAST477

Proteomic databases

PaxDbiP42590.
PRIDEiP42590.

Interactioni

Protein-protein interaction databases

BioGridi4261469. 126 interactors.
DIPiDIP-12235N.
IntActiP42590. 1 interactor.
MINTiMINT-1310596.
STRINGi511145.b3078.

Structurei

3D structure databases

ProteinModelPortaliP42590.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E5D. Bacteria.
COG0531. LUCA.
HOGENOMiHOG000269875.
InParanoidiP42590.
OMAiLWTAAPV.
PhylomeDBiP42590.

Family and domain databases

InterProiIPR002293. AA/rel_permease1.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF13520. AA_permease_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006060. AA_transporter. 1 hit.

Sequencei

Sequence statusi: Complete.

P42590-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDTKRNTIG KFGLLSLTFA AVYSFNNVIN NNIELGLASA PMFFLATIFY
60 70 80 90 100
FIPFCLIIAE FVSLNKNSEA GVYAWVKSSL GGRWAFITAY TYWFVNLFFF
110 120 130 140 150
TSLLPRVIAY ASYAFLGYEY IMTPVATTII SMVLFAFSTW VSTNGAKMLG
160 170 180 190 200
PITSVTSTLM LLLTLSYILL AGTALVGGVQ PADAITVDAM IPNFNWAFLG
210 220 230 240 250
VTTWIFMAAG GAESVAVYVN DVKGGSKSFV KVIILAGIFI GVLYSVSSVL
260 270 280 290 300
INVFVSSKEL KFTGGSVQVF HGMAAYFGLP EALMNRFVGL VSFTAMFGSL
310 320 330 340 350
LMWTATPVKI FFSEIPEGIF GKKTVELNEN GVPARAAWIQ FLIVIPLMII
360 370 380 390 400
PMLGSNTVQD LMNTIINMTA AASMLPPLFI MLAYLNLRAK LDHLPRDFRM
410 420 430 440 450
GSRRTGIIVV SMLIAIFAVG FVASTFPTGA NILTIIFYNV GGIVIFLGFA
460 470
WWKYSKYIKG LTAEERHIEA TPASNVD
Length:477
Mass (Da):52,147
Last modified:October 11, 2004 - v2
Checksum:i4330E433B9EDD9DC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti336 – 350AAWIQ…PLMII → RSVDPVPDRHPADDY in AAA57879 (PubMed:9278503).CuratedAdd BLAST15

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA57879.1.
U00096 Genomic DNA. Translation: AAT48165.1.
AP009048 Genomic DNA. Translation: BAE77128.1.
PIRiC65096.
RefSeqiWP_001285432.1. NZ_LN832404.1.
YP_026200.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48165; AAT48165; b3078.
BAE77128; BAE77128; BAE77128.
GeneIDi947579.
KEGGiecj:JW5512.
eco:b3078.
PATRICi32121572. VBIEscCol129921_3172.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA57879.1.
U00096 Genomic DNA. Translation: AAT48165.1.
AP009048 Genomic DNA. Translation: BAE77128.1.
PIRiC65096.
RefSeqiWP_001285432.1. NZ_LN832404.1.
YP_026200.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP42590.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261469. 126 interactors.
DIPiDIP-12235N.
IntActiP42590. 1 interactor.
MINTiMINT-1310596.
STRINGi511145.b3078.

Protein family/group databases

TCDBi2.A.3.7.4. the amino acid-polyamine-organocation (apc) family.

Proteomic databases

PaxDbiP42590.
PRIDEiP42590.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48165; AAT48165; b3078.
BAE77128; BAE77128; BAE77128.
GeneIDi947579.
KEGGiecj:JW5512.
eco:b3078.
PATRICi32121572. VBIEscCol129921_3172.

Organism-specific databases

EchoBASEiEB2579.
EcoGeneiEG12720. ygjI.

Phylogenomic databases

eggNOGiENOG4105E5D. Bacteria.
COG0531. LUCA.
HOGENOMiHOG000269875.
InParanoidiP42590.
OMAiLWTAAPV.
PhylomeDBiP42590.

Enzyme and pathway databases

BioCyciEcoCyc:YGJI-MONOMER.
ECOL316407:JW5512-MONOMER.

Miscellaneous databases

PROiP42590.

Family and domain databases

InterProiIPR002293. AA/rel_permease1.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF13520. AA_permease_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006060. AA_transporter. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYGJI_ECOLI
AccessioniPrimary (citable) accession number: P42590
Secondary accession number(s): Q2M9C8, Q6BF49
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 11, 2004
Last modified: November 2, 2016
This is version 126 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.