Reviewed, UniProtKB/Swiss-Prot P42517 (CHMU_ENTAG)

Names and origin

Protein names

Recommended name:
    Monofunctional chorismate mutase
    EC=5.4.99.5
Alternative name(s):
    CM-F

Gene names

Name:

aroQ

Organism

Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans)

Taxonomic identifier

549 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pantoea

Protein attributes

Sequence length	181 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	May sequester with cyclohexadienyl dehydratase and perhaps an aminotransferase to form phenylalanine or phenylpyruvate for some as yet unknown function.
Catalytic activity	Chorismate = prephenate.
Pathway	Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.
Subunit structure	Homodimer.
Subcellular location	Periplasm.
Sequence similarities	Contains 1 chorismate mutase domain.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Molecular function	Isomerase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Ref.1
	Chain	21 – 181	161	Monofunctional chorismate mutase		PRO_0000023925
Regions
	Domain	21 – 102	82	Chorismate mutase

Sequences

	Sequence		Length	Mass (Da)
	P42517-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 5F8F77C0D1E2542E	FASTA	181	20,299
	10 20 30 40 50 60 MTHFVAIFFS SLFMCSNVFA GSVSSVSLGS LSSALNERMQ VMKAVAGYKA LHHLPIEDLP 70 80 90 100 110 120 REQVVLDHML QNAQQAGLEP HSVEPFVHAL MNASKTIQYR YRADWLSSPD SAVPVRDLTE 130 140 150 160 170 180 TRQQIQQLDT QLLTAISQRL MTGAFSQEDK EFLMSHLTAP HLSESDKNSL FASLSRIQRQ H

References

[1]

"The aroQ-encoded monofunctional chorismate mutase (CM-F) protein is a periplasmic enzyme in Erwinia herbicola." Xia T., Song J., Zhao G., Aldrich H., Jensen R.A. J. Bacteriol. 175:4729-4737(1993) [PubMed: 8335631] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 21-34. Strain: ATCC 33243 / DSM 4609 / NCPPB 2971.

Cross-references

Sequence databases
EMBLGenBankDDBJ	M95628 Genomic DNA. Translation: AAA73360.1.
PIR	A40607.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	5.4.99.5. 3054.
Family and domain databases
InterPro	IPR002701. Chorismate_mut. IPR008240. Chorismate_mutase_periplasmic. [Graphical view]
Pfam	PF01817. CM_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR01806. CM_mono2. 1 hit.
PROSITE	PS51168. CHORISMATE_MUT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CHMU_ENTAG

Accession

Primary (citable) accession number: P42517

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	June 16, 2009
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)