P42392 (TRPD_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Anthranilate phosphoribosyltransferase
EC=2.4.2.18

Gene names

Name:	trpD
Ordered Locus Names:	BUsg_269

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Schizaphis graminum)

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00211
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5. HAMAP-Rule MF_00211
Sequence similarities	Belongs to the anthranilate phosphoribosyltransferase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	anthranilate phosphoribosyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 335	335	Anthranilate phosphoribosyltransferase HAMAP-Rule MF_00211		PRO_0000154435

Sequences

	Sequence		Length	Mass (Da)
	P42392 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: E33F51F2126013AD	FASTA	335	38,090
	10 20 30 40 50 60 MQNIFNKIYE SKSLNQEESY QLFKSIALGK INEIQLSSIL TAMQMHGESE KEILGAIYAF 70 80 90 100 110 120 SERMKFFPRP NYIFSDIVGT GGDSKNTINV STSSAFVAAS CGFKIIKHCN KGVSSKSGSS 130 140 150 160 170 180 DLLNKFKINL NTSLENSKKI LDKLNICFLF APKYHSVFKY ASKTRSILKI KTIFNLLGPF 190 200 210 220 230 240 LNPSRPPLTL IGVYKKDLVN PMSRILKKLK YQRGIILHGD DTDEVTLHGT TYISELLNNK 250 260 270 280 290 300 IYSYELEPED FGIKRHSKSI FVEYSPEENY HIIKKTMQGK GEKLHEELIA VNVALLLKIF 310 320 330 GHENLKENTK IALKKIRSGD VYKHIMQVSN MLKED

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular cloning and nucleotide sequence of a putative trpDC(F)BA operon in Buchnera aphidicola (endosymbiont of the aphid Schizaphis graminum)." Munson M.A., Baumann P. J. Bacteriol. 175:6426-6432(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z19055 Genomic DNA. Translation: CAA79498.1. AE013218 Genomic DNA. Translation: AAM67827.1.
PIR	A49897.
RefSeq	NP_660616.1. NC_004061.1.
3D structure databases
ProteinModelPortal	P42392.
ModBase	Search...
Protein-protein interaction databases
STRING	198804.BUsg269.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM67827; AAM67827; BUsg_269.
GeneID	1005471.
KEGG	bas:BUsg269.
PATRIC	21247343. VBIBucAph100086_0281.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0547.
KO	K00766.
OMA	AMKHAIG.
ProtClustDB	PRK00188.
Enzyme and pathway databases
BioCyc	BAPH198804:GHMG-283-MONOMER.
UniPathway	UPA00035; UER00041.
Family and domain databases
Gene3D	3.40.1030.10. 2 hits.
HAMAP	MF_00211. TrpD.
InterPro	IPR005940. Anthranilate_Pribosyl_Tfrase. IPR000312. Glycosyl_Trfase_fam3. IPR017459. Glycosyl_Trfase_fam3_N_dom. [Graphical view]
Pfam	PF02885. Glycos_trans_3N. 1 hit. PF00591. Glycos_transf_3. 1 hit. [Graphical view]
SUPFAM	SSF47648. Glyco_trans_3. 1 hit. SSF52418. Glyco_trans_3. 1 hit.
TIGRFAMs	TIGR01245. trpD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPD_BUCAP

Accession

Primary (citable) accession number: P42392

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 29, 2013
This is version 92 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program