Reviewed,
UniProtKB/Swiss-Prot P42388 (TRPG_BUCAP)
Last modified
November 3, 2009.
Version 60.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Anthranilate synthase component 2 EC=4.1.3.27 Alternative name(s): Anthranilate synthase component II Glutamine amido-transferase | ||||
| Gene names |
| ||||
| Encoded on | Plasmid pBSc | ||||
| Organism | Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 98794 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera |
Protein attributes
| Sequence length | 196 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Predicted. |
General annotation (Comments)
| Catalytic activity | Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate. |
| Pathway | Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5. |
| Subunit structure | Tetramer of two components I and two components II. |
| Miscellaneous | Component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity. |
| Sequence similarities | Contains 1 glutamine amidotransferase type-1 domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis |
| Domain | Glutamine amidotransferase |
| Molecular function | Lyase |
| Technical term | Complete proteome Plasmid |
| Gene Ontology (GO) | |
| Biological process | glutamine metabolic process Inferred from electronic annotation. Source: UniProtKB-KW tryptophan biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | anthranilate synthase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 196 | 196 | Anthranilate synthase component 2 | PRO_0000056873 | |||||
Regions | |||||||||
| Domain | 3 – 196 | 194 | Glutamine amidotransferase type-1 | ||||||
Sites | |||||||||
| Active site | 84 | 1 | By similarity | ||||||
| Active site | 170 | 1 | By similarity | ||||||
| Active site | 172 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Amplification of trpEG: adaptation of Buchnera aphidicola to an endosymbiotic association with aphids." Lai C.-Y., Baumann L., Baumann P. Proc. Natl. Acad. Sci. U.S.A. 91:3819-3823(1994) [PubMed: 8170994] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| Z21938 Genomic DNA. Translation: CAA79932.1. | |
| PIR | I40053. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1I1Q based on UniProtKB P00905. |
| ModBase | Search... |
Genome annotation databases | |
| GenomeReviews | Gene locus BUsg_PT2 in contig Z21938_GR. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P42388. |
| OMA | RISHDNE. |
Family and domain databases | |
| InterPro | IPR006220. Anth_synthII. IPR011702. GATASE. IPR017926. GATASE_1. IPR000991. GATase_class1_C. IPR006221. TrpG_papA. [Graphical view] |
| Pfam | PF00117. GATase. 1 hit. [Graphical view] |
| PRINTS | PR00097. ANTSNTHASEII. PR00096. GATASE. |
| TIGRFAMs | TIGR00566. trpG_papA. 1 hit. |
| PROSITE | PS51273. GATASE_TYPE_1. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | TRPG_BUCAP | ||||||||
| Accession | Primary (citable) accession number: P42388 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Buchnera aphidicola (subsp. Schizaphis graminum) Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


