P42365 (TPX_STREE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Probable thiol peroxidase EC=1.11.1.-
Organism	Streptococcus pneumoniae
Taxonomic identifier	1313 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	50 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has antioxidant activity. Could remove peroxides or H2O2 By similarity. HAMAP-Rule MF_00269
Sequence similarities	Belongs to the AhpC/TSA family. Tpx subfamily.

Ontologies

Keywords
Molecular function	Antioxidant Oxidoreductase Peroxidase
Gene Ontology (GO)
Molecular_function	peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – ›50	›49	Probable thiol peroxidase HAMAP-Rule MF_00269		PRO_0000187914
Experimental info
	Non-terminal residue	50	1

Sequences

	Sequence		Length	Mass (Da)
	P42365 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 4FF8FB857F648B33	FASTA	50	5,355
	10 20 30 40 50 MTTFLGNPVT FTGSQLQVGD TAHDFSLTTP NLEKKSLADF AGKKKVLSVI

References

[1]

"Cloning and nucleotide sequence analysis of psaA, the Streptococcus pneumoniae gene encoding a 37-kilodalton protein homologous to previously reported Streptococcus sp. adhesins." Sampson J.S., O'Connor S.P., Stinson A.R., Tharpe J.A., Russell H. Infect. Immun. 62:319-324(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: R36A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L19055 Unassigned DNA. Translation: AAA16799.1.
3D structure databases
ProteinModelPortal	P42365.
SMR	P42365. Positions 1-50.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.40.30.10. 1 hit.
HAMAP	MF_00269. Tpx.
InterPro	IPR012336. Thioredoxin-like_fold. [Graphical view]
SUPFAM	SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS01265. TPX. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TPX_STREE

Accession

Primary (citable) accession number: P42365

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	January 23, 2007
Last modified:	April 3, 2013
This is version 67 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program